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The Emerging Role Of Nrf2 In Mitochondrial Function

Oxidants are generally produced in a controlled manner in order to regulate essential processes in the human body, including cell division, inflammation, immune function, autophagy, and stress response. However, the uncontrolled production of these oxidants can contribute to oxidative stress, which may affect cellular function, leading to the development of toxicity, chronic disease and cancer. The human body’s protective antioxidant mechanisms are regulated by a series of vital pathways that control the cell’s response to oxidants. The nuclear factor erythroid 2-related factor, otherwise known as Nrf2, is an emerging regulator of cellular resistance to oxidants. The purpose of the article below is to discuss and demonstrate the emerging role of Nrf2 in mitochondrial function. 

Abstract

The transcription factor NF-E2 p45-related factor 2 (Nrf2; gene name NFE2L2) allows adaptation and survival under conditions of stress by regulating the gene expression of diverse networks of cytoprotective proteins, including antioxidant, anti-inflammatory, and detoxification enzymes as well as proteins that assist in the repair or removal of damaged macromolecules. Nrf2 has a crucial role in the maintenance of cellular redox homeostasis by regulating the biosynthesis, utilization, and regeneration of glutathione, thioredoxin, and NADPH and by controlling the production of reactive oxygen species by mitochondria and NADPH oxidase. Under homeostatic conditions, Nrf2 affects the mitochondrial membrane potential, fatty acid oxidation, availability of substrates (NADH and FADH2/succinate) for respiration, and ATP synthesis. Under conditions of stress or growth factor stimulation, activation of Nrf2 counteracts the increased reactive oxygen species production in mitochondria via transcriptional upregulation of uncoupling protein 3 and influences mitochondrial biogenesis by maintaining the levels of nuclear respiratory factor 1 and peroxisome proliferator-activated receptor γ coactivator 1α, as well as by promoting purine nucleotide biosynthesis. Pharmacological Nrf2 activators, such as the naturally occurring isothiocyanate sulforaphane, inhibit oxidant-mediated opening of the mitochondrial permeability transition pore and mitochondrial swelling. Curiously, a synthetic 1,4-diphenyl-1,2,3-triazole compound, originally designed as an Nrf2 activator, was found to promote mitophagy, thereby contributing to the overall mitochondrial homeostasis. Thus, Nrf2 is a prominent player in supporting the structural and functional integrity of the mitochondria, and this role is particularly crucial under conditions of stress.

Keywords: Bioenergetics, Cytoprotection, Keap1, Mitochondria, Nrf2, Free radicals

Highlights

  • Nrf2 has a crucial role in maintaining cellular redox homeostasis.
  • Nrf2 affects the mitochondrial membrane potential and ATP synthesis.
  • Nrf2 influences mitochondrial fatty acid oxidation.
  • Nrf2 supports the structural and functional integrity of the mitochondria.
  • Nrf2 activators have beneficial effects when mitochondrial function is compromised.

Introduction

The transcription factor NF-E2 p45-related factor 2 (Nrf2; gene name NFE2L2) regulates the expression of networks of genes encoding proteins with diverse cytoprotective activities. Nrf2 itself is controlled primarily at the level of protein stability. Under basal conditions, Nrf2 is a short-lived protein that is subjected to continuous ubiquitination and proteasomal degradation. There are three known ubiquitin ligase systems that contribute to the degradation of Nrf2. Historically, the first negative regulator of Nrf2 to be discovered was Kelch-like ECH-associated protein 1 (Keap1) [1], a substrate adaptor protein for Cullin 3 (Cul3)/Rbx1 ubiquitin ligase [2], [3], [4]. Keap1 uses a highly efficient cyclic mechanism to target Nrf2 for ubiquitination and proteasomal degradation, during which Keap1 is continuously regenerated, allowing the cycle to proceed (Fig. 1A) [5]. Nrf2 is also subjected to degradation mediated by glycogen synthase kinase (GSK)3/β-TrCP-dependent Cul1-based ubiquitin ligase [6], [7]. Most recently, it was reported that, during conditions of endoplasmic reticulum stress, Nrf2 is ubiquitinated and degraded in a process mediated by the E3 ubiquitin ligase Hrd1 [8].

Figure 1 The cyclic sequential binding and regeneration model for Keap1-mediated degradation of Nrf2. (A) Nrf2 binds sequentially to a free Keap1 dimer: first through its high-affinity ETGE (red sticks) binding domain and then through its low-affinity DLG (black sticks) binding domain. In this conformation of the protein complex, Nrf2 undergoes ubiquitination and is targeted for proteasomal degradation. Free Keap1 is regenerated and able to bind to newly translated Nrf2, and the cycle begins again.(B) Inducers (white diamonds) react with sensor cysteines of Keap1 (blue sticks), leading to a conformational change and impaired substrate adaptor activity. Free Keap1 is not regenerated, and the newly synthesized Nrf2 accumulates and translocates to the nucleus.

In addition to serving as a ubiquitin ligase substrate adaptor protein, Keap1 is also the sensor for a wide array of small-molecule activators of Nrf2 (termed inducers) [9]. Inducers block the cycle of Keap1-mediated degradation of Nrf2 by chemically modifying specific cysteine residues within Keap1 [10], [11] or by directly disrupting the Keap1:Nrf2 binding interface [12], [13]. Consequently, Nrf2 is not degraded, and the transcription factor accumulates and translocates to the nucleus (Fig. 1B), where it forms a heterodimer with a small Maf protein; binds to antioxidant-response elements, the upstream regulatory regions of its target genes; and initiates transcription [14], [15], [16]. The battery of Nrf2 targets comprises proteins with diverse cytoprotective functions, including enzymes of xenobiotic metabolism, proteins with antioxidant and anti-inflammatory functions, and proteasomal subunits, as well as proteins that regulate cellular redox homeostasis and participate in intermediary metabolism.

Nrf2: a Master Regulator of Cellular Redox Homeostasis

The function of Nrf2 as a master regulator of cellular redox homeostasis is widely recognized. The gene expression of both the catalytic and the regulatory subunits of γ-glutamyl cysteine ligase, the enzyme catalyzing the rate-limiting step in the biosynthesis of reduced glutathione (GSH), is directly regulated by Nrf2 [17]. The xCT subunit of system xc-, which imports cystine into cells, is also a direct transcriptional target of Nrf2 [18]. In the cell, cystine undergoes conversion to cysteine, a precursor for the biosynthesis of GSH. In addition to its role in GSH biosynthesis, Nrf2 provides the means for the maintenance of glutathione in its reduced state by the coordinated transcriptional regulation of glutathione reductase 1 [19], [20], which reduces oxidized glutathione to GSH using reducing equivalents from NADPH. The required NADPH is provided by four principal NADPH-generating enzymes, malic enzyme 1 (ME1), isocitrate dehydrogenase 1 (IDH1), glucose-6-phosphate dehydrogenase (G6PD), and 6-phosphogluconate dehydrogenase (PGD), all of which are transcriptionally regulated in part by Nrf2 (Fig. 2) [21], [22], [23], [24]. Curiously, Nrf2 also regulates the inducible gene expression of the cytosolic, microsomal, and mitochondrial forms of aldehyde dehydrogenase [25], which use NAD(P)+ as a cofactor, giving rise to NAD(P)H. Indeed, the levels of NADPH and the NADPH/NADP+ ratio are lower in embryonic fibroblasts isolated from Nrf2-knockout (Nrf2-KO) mice compared to cells from their wild-type (WT) counterparts, and the NADPH levels decrease upon Nrf2 knockdown in cancer cell lines with constitutively active Nrf2 [26]. As expected, the levels of GSH are lower in cells in which Nrf2 has been disrupted; conversely, Nrf2 activation by genetic or pharmacological means leads to GSH upregulation [27], [28], [29]. Importantly, Nrf2 also regulates the gene expression of thioredoxin [30], [31], [32], thioredoxin reductase 1 [28], [29], [32], [33], and sulfiredoxin [34], which are essential for the reduction of oxidized protein thiols.

Figure 2 The role of Nrf2 in the metabolism of rapidly proliferating cells. Nrf2 is a positive regulator of genes encoding enzymes in both the oxidative arm [i.e., glucose-6-phosphate dehydrogenase (G6PD) and 6-phosphogluconate dehydrogenase (PGD)] and the nonoxidative arm [i.e., transaldolase 1 (TALDO1) and transketolase (TKT)] of the pentose phosphate pathway. G6PD and PGD generate NADPH. Nrf2 also regulates the gene expression of the other two NADPH-generating enzymes, malic enzyme 1 (ME1) and isocitrate dehydrogenase 1 (IDH1). The gene expression of phosphoribosyl pyrophosphate amidotransferase (PPAT), which catalyzes the entry into the de novo purine biosynthetic pathway, is also positively regulated by Nrf2, as is the expression of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2), a mitochondrial enzyme with a critical role in providing one-carbon units for de novo purine biosynthesis. Pyruvate kinase (PK) is negatively regulated by Nrf2 and is expected to favor the buildup of glycolytic intermediates and, together with G6PD, metabolite channeling through the pentose phosphate pathway and the synthesis of nucleic acids, amino acids, and phospholipids. Nrf2 negatively regulates the gene expression of ATP-citrate lyase (CL), which may increase the availability of citrate for mitochondrial utilization or (through isocitrate) for IDH1. Red and blue indicate positive and negative regulation, respectively. The mitochondrion is shown in gray. Metabolite abbreviations: G-6-P, glucose 6-phosphate; F-6-P, fructose 6-phosphate; F-1,6-BP, fructose 1,6-bisphosphate; GA-3-P, glyceraldehyde 3-phosphate; 3-PG, 3-phosphoglycerate; PEP, phosphoenolpyruvate; 6-P-Gl, 6-phosphogluconolactone; 6-PG, 6-phosphogluconate; R-5-P, ribulose 5-phosphate; PRPP, 5-phosphoribosyl-α-1-pyrophosphate; THF, tetrahydrofolate; IMP, inosine monophosphate; AMP, adenosine monophosphate; GMP, guanosine monophosphate.

Given the crucial role of Nrf2 as a master regulator of cellular redox homeostasis, it is not surprising that, compared to WT cells, the levels of reactive oxygen species (ROS) are higher in cells in which Nrf2 has been disrupted (Nrf2-KO) [35]. This difference is particularly striking upon challenge with agents causing oxidative stress. Moreover, cells deficient in Nrf2 are much more sensitive to the toxicity of oxidants of various types and cannot be protected by Nrf2 inducers, which, under the same conditions, provide efficient and long-lasting protection to WT cells [29], [36], [37]. In addition to the overall cellular redox homeostasis, Nrf2 is also critical for the maintenance of the mitochondrial redox homeostasis. Thus, compared to WT, the total mitochondrial NADH pool is significantly increased in Keap1-KO and dramatically decreased in Nrf2-KO cells [35].

Using live cell imaging, we recently monitored the rates of ROS production in primary glioneuronal cocultures and brain tissue slices isolated from WT, Nrf2-KO, or Keap1-knockdown (Keap1-KD) mice [38]. As expected, the rate of ROS production was faster in Nrf2-KO cells and tissues compared to their WT counterparts. However, we made the unexpected observation that, compared to WT, Keap1-KD cells also have higher rates of ROS production, although the magnitude of the difference between the WT and the Keap1-KD genotypes was smaller than that between WT and Nrf2-KO. We then analyzed the mRNA levels of NOX2 and NOX4, the catalytic subunits of the two NADPH oxidase (NOX) isoforms that have been implicated in brain pathology, and found that NOX2 is dramatically increased under conditions of Nrf2 deficiency, whereas NOX4 is upregulated when Nrf2 is constitutively activated, although to a smaller extent. Quantitatively, the magnitude of upregulation in cells and tissues from the mutant mice parallels the corresponding increases in ROS production [38]. Interestingly, not only does Nrf2 regulate NADPH oxidase, but the ROS produced by NADPH oxidase can activate Nrf2, as shown in pulmonary epithelial cells and cardiomyocytes [39], [40]. Furthermore, a very recent study has demonstrated that the NADPH oxidase-dependent activation of Nrf2 constitutes an important endogenous mechanism for protection against mitochondrial damage and cell death in the heart during chronic pressure overload [41].

In addition to the catalytic activity of NADPH oxidase, mitochondrial respiration is another major intracellular source of ROS.By use of the mitochondria-specific probe MitoSOX, we have examined the contribution of ROS of mitochondrial origin to the overall ROS production in primary glioneuronal cocultures isolated from WT, Nrf2-KO, or Keap1-KD mice [38]. As expected, Nrf2-KO cells had higher rates of mitochondrial ROS production than WT. In agreement with the findings for the overall ROS production, the rates of mitochondrial ROS production in Keap1-KD were also higher compared to WT cells. Importantly, blocking complex I with rotenone caused a dramatic increase in mitochondrial ROS production in both WT and Keap1-KD cells, but had no effect in Nrf2-KO cells. In contrast to the expected increase in mitochondrial ROS production in WT cells after addition of pyruvate (to enhance the availability of NADH, increase the mitochondrial membrane potential,and normalize respiration), the production of ROS decreased in Nrf2-KO cells. Together, these findings strongly suggest that, in the absence of Nrf2: (i) the activity of complex I is impaired, (ii) the impaired activity of complex I is due to limitation of substrates, and (iii) the impaired activity of complex I is one of the main reasons for the increased mitochondrial ROS production, possibly owing to reverse electron flow from complex II.

Nrf2 Affects Mitochondrial Membrane Potential and Respiration

The mitochondrial membrane potential (Δψm) is a universal indicator of mitochondrial health and the metabolic state of the cell. In a healthy cell, Δψm is maintained by the mitochondrial respiratory chain. Interestingly, a stable isotopic labeling with amino acids in culture-based proteomics study in the estrogen receptor-negative nontumorigenic human breast epithelial MCF10A cell line has shown that the mitochondrial electron transport chain component NDUFA4 is upregulated by pharmacological activation (by sulforaphane) of Nrf2, whereas genetic upregulation of Nrf2 (by Keap1 knockdown) leads to downregulation of the cytochrome c oxidase subunits COX2 and COX4I1 [42]. A study of the liver proteome using two-dimensional gel electrophoresis and matrix-assisted laser desorption/ionization mass spectrometry has found that Nrf2 regulates the expression of ATP synthase subunit α [43]. In addition, the mitochondrial protein DJ-1, which plays a role in the maintenance of the activity of complex I [44], has been reported to stabilize Nrf2 [45], [46], although the neuroprotective effects of pharmacological or genetic activation of Nrf2 are independent of DJ-1 [47]. However, the consequences of these observations for mitochondrial function have not been investigated.

In agreement with the impaired activity of complex I under conditions of Nrf2 deficiency, the basal Δψm is lower in Nrf2-KO mouse embryonic fibroblasts (MEFs) and cultured primary glioneuronal cells in comparison with their WT counterparts (Fig. 3,inset) [35]. In contrast, the basal Δψm is higher when Nrf2 is genetically constitutively upregulated (by knockdown or knockout of Keap1). These differences in Δψm among the genotypes indicate that respiration is affected by the activity of Nrf2. Indeed, evaluation of the oxygen consumption in the basal state has revealed that, compared to WT, the oxygen consumption is lower in Nrf2-KO and Keap1-KO MEFs, by ~50 and ~35%, respectively.

Figure 3 Proposed mechanism for compromised mitochondrial function under conditions of Nrf2 deficiency. (1) The decreased levels of ME1, IDH1, G6PD, and PGD result in lower NADPH levels. (2) The levels of GSH are also low. (3) The low activity of ME1 may decrease the pool of pyruvate entering the mitochondria. (4) The generation of NADH is slower, leading to impaired activity of complex I and increased mitochondrial ROS production. (5) The reduction of FAD to FADH2 in mitochondrial proteins is also decreased, lowering the electron flow from FADH2 to UbQ and into complex III. (6) The slower formation of UbQH2 may lower the enzyme activity of succinate dehydrogenase. (7) The increased levels of ROS may further inhibit the activity of complex II. (8) The lower efficiency of fatty acid oxidation contributes to the decreased substrate availability for mitochondrial respiration. (9) Glycolysis is enhanced as a compensatory mechanism for the decreased ATP production in oxidative phosphorylation. (10) ATP synthase operates in reverse to maintain Δψm. Red and blue indicate upregulation and downregulation, respectively. The boxes signify availability of experimental evidence. The inset shows images of mitochondria of WT and Nrf2-KO cortical astrocytes visualized by the potentiometric fluorescent probe tetramethylrhodamine methyl ester (TMRM; 25 nM). Scale bar, 20 µm.

These differences in Δψm and respiration among the genotypes are reflected by the rate of utilization of substrates for mitochondrial respiration. Application of substrates for the tricarboxylic acid (TCA) cycle (malate/pyruvate, which in turn increase the production of the complex I substrate NADH) or methyl succinate, a substrate for complex II, causes a stepwise increase in Δψm in both WT and Keap1-KD neurons, but the rate of increase is higher in Keap1-KD cells. More importantly, the shapes of the response to these TCA cycle substrates are different between the two genotypes, whereby the rapid rise in Δψm in Keap1-KD cells upon substrate addition is followed by a quick drop rather than a plateau, suggesting an unusually fast substrate consumption. These findings are in close agreement with the much lower (by 50–70%) levels of malate, pyruvate, and succinate that have been observed after a 1-h pulse of [U-13C6]glucose in Keap1-KO compared to WT MEF cells [24]. In Nrf2-KO neurons, only pyruvate is able to increase the Δψm, whereas malate and methyl succinate cause mild depolarization. The effect of Nrf2 on mitochondrial substrate production seems to be the main mechanism by which Nrf2 affects mitochondrial function. The mitochondrial NADH redox index (the balance between consumption of NADH by complex I and production of NADPH in the TCA cycle) is significantly lower in Nrf2-KO cells in comparison with their WT counterparts, and furthermore, the rates of regeneration of the pools of NADH and FADH2 after inhibition of complex IV (by use of NaCN) are slower in the mutant cells.

In mitochondria isolated from murine brain and liver, supplementation of substrates for complex I or for complex II increases the rate of oxygen consumption more strongly when Nrf2 is activated and less efficiently when Nrf2 is disrupted [35]. Thus, malate induces a higher rate of oxygen consumption in Keap1-KD compared to WT, but its effect is weaker in Nrf2-KO mitochondria. Similarly, in the presence of rotenone (when complex I is inhibited), succinate activates oxygen consumption to a greater extent in Keap1-KD compared to WT, whereas the response in Nrf2-KO mitochondria is diminished. In addition, Nrf2-KO primary neuronal cultures and mice are more sensitive to the toxicity of the complex II inhibitors 3-nitropropionic acid and malonate, whereas intrastriatal transplantation of Nrf2-overexpressing astrocytes is protective [48], [49]. Similarly, Nrf2-KO mice are more sensitive to, whereas genetic or pharmacological activation of Nrf2 has protective effects against, neurotoxicity caused by the complex I inhibitor 1-methyl-4-phenylpyridinium ion in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine animal model of Parkinson׳s disease [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61].

The respiratory control ratio (RCR), the ratio of State 3 (ADP-stimulated) to State 4 respiration (no ADP present), is decreased in the absence of Nrf2, but the RCR is similar between Keap1-KD and WT mitochondria [35]. As the RCR is an indication of the degree of coupling of the mitochondrial respiratory chain activity to oxidative phosphorylation, this finding indicates that the higher rate of respiration in Keap1-KD mitochondria is not due to uncoupling of oxidative phosphorylation. It further suggests that oxidative phosphorylation is more efficient when Nrf2 is activated. The higher rate of respiration in Keap1-KD mitochondria is consistent with the higher levels of mitochondrial ROS production [38] as higher respiration rates may lead to increased electron leak. However, under conditions of oxidative stress, the increased ROS production is counteracted by the Nrf2-dependent transcriptional upregulation of uncoupling protein 3 (UCP3), which increases the proton conductance of the mitochondrial inner membrane and consequently decreases the production of superoxide [62]. Very recently, it was shown that the lipid peroxidation product 4-hydroxy-2-nonenal mediates the Nrf2-dependent upregulation of UCP3 in cardiomyocytes; this might be particularly important for protection under conditions of oxidative stress such as those during ischemia–reperfusion [63].

Nrf2 Affects the Efficiency of Oxidative Phosphorylation and the Synthesis of ATP

In agreement with the effect of Nrf2 on respiration, in brain and liver mitochondria, Nrf2 deficiency results in a decreased efficiency of oxidative phosphorylation (as estimated by the ratio of ADP to oxygen, which is consumed for ATP synthesis), whereas Nrf2 activation (Keap1-KD) has the opposite effect [35]. Compared to WT, the ATP levels are significantly higher in cells with constitutive upregulation of Nrf2 and lower when Nrf2 is knocked down [64] or disrupted [35]. Furthermore, the use of inhibitors of oxidative phosphorylation (oligomycin) or glycolysis (iodoacetic acid) has revealed that Nrf2 changes the way by which cells produce ATP. Thus, in WT neurons, oligomycin causes a complete drop in ATP and iodoacetic acid has no further effect. Remarkably, in Nrf2-KO cells, oligomycin increases the ATP levels, which are then slowly, but completely, depleted by iodoacetic acid, indicating that in the absence of Nrf2, glycolysis, and not oxidative phosphorylation, is the main source of ATP production. Interestingly, despite the increased efficiency of oxidative phosphorylation in Keap1-KD cells, addition of oligomycin results in an ~80% decrease in ATP levels, and iodoacetic acid causes a further ~20% decrease. Thus, either Nrf2 deficiency or its constitutive activation reduces the contribution of oxidative phosphorylation and increases the contribution of glycolysis toward the synthesis of ATP. This effect is particularly pronounced when Nrf2 is absent and is consistent with the dependence of the Δψm on the presence of glucose in the medium [35] and the increased levels of glycolytic intermediates (G-6-P, F-6-P, dihydroxyacetone phosphate, pyruvate, and lactate) after knockdown of Nrf2 [24].

The increase in ATP levels after inhibition of the F1F0-ATPase by oligomycin indicates that in the absence of Nrf2, the F1F0-ATPase functions as an ATPase and not an ATP synthase, i.e., it operates in reverse. Such reversal in activity most likely reflects the need to pump protons across the inner mitochondrial membrane in an attempt to maintain the Δψm, which is crucial for the functional integrity of this organelle. The reversal of the function of the F1F0-ATPase is also evidenced by the observed mitochondrial depolarization upon oligomycin administration to Nrf2-KO cells, which is in sharp contrast to the hyperpolarization occurring in their WT or Keap1-deficient counterparts [35]. Overall, it seems that under conditions of Nrf2 deficiency ATP is produced primarily in glycolysis, and this ATP is then used in part by the F1F0-ATPase to maintain the Δψm.

Nrf2 Enhances Mitochondrial Fatty Acid Oxidation

The effect of Nrf2 deficiency on the Δψm is particularly pronounced when cells are incubated in medium without glucose, and the Δψm is ~50% lower in Nrf2-KO compared to WT cells [35]. Under conditions of glucose deprivation, mitochondrial fatty acid oxidation (FAO) is a major provider of substrates for respiration and oxidative phosphorylation, suggesting that Nrf2 may affect FAO. Indeed, the efficiency of FAO for both the long-chain (C16:0) saturated fatty acid palmitic acid and the short-chain (C6:0) hexanoic acid is higher in Keap1-KO MEFs and isolated heart and liver mitochondria than in their WT counterparts, whereas it is lower in Nrf2-KO cells and mitochondria [65]. These effects are also highly relevant to humans: indeed, metabolic changes indicative of better integration of FAO with the activity of the TCA cycle have been reported to occur in human intervention studies with diets rich in glucoraphanin, the precursor of the classical Nrf2 activator sulforaphane [66].

During the first step of mitochondrial FAO, the pro-R hydrogen of the β-carbon leaves as a hydride that reduces the FAD cofactor to FADH2, which in turn transfers electrons to ubiquinone (UbQ) in the respiratory chain, ultimately contributing to ATP production. Whereas stimulation of FAO by palmitoylcarnitine in the absence of glucose causes the expected increase in the ATP levels in WT and Keap1-KO cells, with the ATP rise being faster in Keap1-KO cells, the identical treatment produces no ATP changes in Nrf2-KO MEFs [65]. This experiment demonstrates that, in the absence of Nrf2, FAO is suppressed, and furthermore, it implicates suppression of FAO as one of the reasons for the lower ATP levels under conditions of Nrf2 deficiency [35], [64].

Notably, human 293 T cells in which Nrf2 has been silenced have a lower expression of CPT1 and CPT2[67], two isoforms of carnitine palmitoyltransferase (CPT), the rate-limiting enzyme in mitochondrial FAO. In agreement, the mRNA levels of Cpt1 are lower in livers of Nrf2-KO compared to WT mice [68]. CPT catalyzes the transfer of the acyl group of a long-chain fatty acyl-CoA from coenzyme A to l-carnitine and thus permits the import of acylcarnitine from the cytoplasm into the mitochondria. Although this has not been examined to date, it is possible that in addition to the transcriptional effects on CPT1 expression, Nrf2 may also affect the function of this enzyme by controlling the levels of its main allosteric inhibitor, malonyl-CoA. This is because, by a mechanism that is currently unclear, Nrf2 regulates negatively the expression of stearoyl CoA desaturase (SCD) [69] and citrate lyase (CL) [69], [70]. Curiously, knockout or inhibition of SCD leads to increased phosphorylation and activation of AMP-activated protein kinase (AMPK) [71], [72], [73], and it can be speculated that, in the absence of Nrf2, the SCD levels will increase, in turn lowering AMPK activity. This could be further compounded by the reduced protein levels of AMPK that have been observed in livers of Nrf2-KO mice [68], a finding that is in close agreement with the increased AMPK levels, which have been reported in livers of Keap1-KD mice [74]. One consequence of the decreased AMPK activity is the relief of its inhibitory phosphorylation (at Ser79) of acetyl-CoA carboxylase (ACC) [75], which could be further transcriptionally upregulated in the absence of Nrf2 because it is downregulated by Nrf2 activation [70]. The high ACC activity, in combination with the upregulated CL expression that will increase the production of acetyl-CoA, the substrate for ACC, may ultimately increase the levels of the ACC product, malonyl-CoA. The high levels of malonyl-CoA will inhibit CPT, thereby decreasing the transport of fatty acids into the mitochondria. Finally, Nrf2 positively regulates the expression of CD36 [76], a translocase that imports fatty acids across plasma and mitochondrial membranes. Thus, one mechanism by which Nrf2 may affect the efficiency of mitochondrial FAO is by regulating the import of long-chain fatty acids into the mitochondria.

In addition to direct transcriptional regulation, Nrf2 may also alter the efficiency of mitochondrial FAO by its effects on the cellular redox metabolism. This may be especially relevant when Nrf2 activity is low or absent, conditions that shift the cellular redox status toward the oxidized state. Indeed, several FAO enzymes have been identified as being sensitive to redox changes. One such enzyme is very long-chain acyl-CoA dehydrogenase (VLCAD), which contributes more than 80% to the palmitoyl-CoA dehydrogenation activity in human tissues [77]. Interestingly, Hurd et al. [78] have shown that VLCAD contains cysteine residues that significantly change their redox state upon exposure of isolated rat heart mitochondria to H2O2. Additionally, S-nitrosylation of murine hepatic VLCAD at Cys238 improves the catalytic efficiency of the enzyme [79], and it is likely that oxidation of the same cysteine may have the opposite effect, ultimately lowering the efficiency of mitochondrial FAO. It is therefore possible that, although the expression levels of VLCAD are not significantly different in WT, Nrf2-KO, or Keap1-KO MEFs [65], the enzyme activity of VLCAD could be lower in the absence of Nrf2 owing to the higher levels of ROS.

Based on all of these findings, it can be proposed that (Fig. 3): in the absence of Nrf2, the NADPH levels are lower owing to decreased expression of ME1, IDH1, G6PD, and PGD. The levels of reduced glutathione are also lower owing to decreased expression of enzymes that participate in its biosynthesis and regeneration and the lower levels of NADPH that are required for the conversion of the oxidized to the reduced form of glutathione. The low expression of ME1 will decrease the pool of pyruvate entering the mitochondria, with glycolysis becoming the major source of pyruvate. The generation of NADH is slower, leading to impaired activity of complex I and increased mitochondrial ROS production. The reduction of FAD to FADH2 is also slower, at least in part owing to less efficient fatty acid oxidation, compromising the electron flow from FADH2 to UbQ and into complex III. As UbQH2 is an activator of succinate dehydrogenase [80], slowing down its formation may lower the enzyme activity of succinate dehydrogenase. The increased levels of superoxide and hydrogen peroxide can inhibit complex II activity further [81]. The lower efficiency of fatty acid oxidation contributes to the decreased substrate availability for mitochondrial respiration and ATP production in oxidative phosphorylation. As a compensatory mechanism, glycolysis is enhanced. ATP synthase functions in reverse, as an ATPase, in an attempt to maintain the Δψm.

Nrf2 and Mitochondrial Biogenesis

It has been reported that, compared to WT, the livers of Nrf2-KO mice have a lower mitochondrial content (as determined by the ratio of mitochondrial to nuclear DNA); this is further decreased by a 24-h fast in both WT and Nrf2-KO mice; in contrast, although no different from WT under normal feeding conditions, the mitochondrial content in mice with high Nrf2 activity is not affected by fasting [82]. Interestingly, supplementation with the Nrf2 activator (R)-α-lipoic acid [83], [84], [85] promotes mitochondrial biogenesis in 3T3-L1 adipocytes [86]. Two classes of nuclear transcriptional regulators play critical roles in mitochondrial biogenesis. The first class are transcription factors, such as nuclear respiratory factors11 and 2, which control the expression of genes encoding subunits of the five respiratory complexes, mitochondrial translational components, and heme biosynthetic enzymes that are localized to the mitochondrial matrix [88]. Piantadosi et al. [89] have shown that the Nrf2-dependent transcriptional upregulation of nuclear respiratory factor 1 promotes mitochondrial biogenesis and protects against the cytotoxicity of the cardiotoxic anthracycline chemotherapeutic agent doxorubicin. In contrast, Zhang et al. [82] have reported that genetic activation of Nrf2 does not affect the basal mRNA expression of nuclear respiratory factor 1 in the murine liver.

The second class of nuclear transcriptional regulators with critical functions in mitochondrial biogenesis are transcriptional coactivators, such as peroxisome proliferator-activated receptor γ coactivators (PGC)1α and 1β, which interact with transcription factors, the basal transcriptional and RNA-splicing machinery, and histone-modifying enzymes [88], [90], [91]. The expression of the PGC1 family of coactivators is influenced by numerous environmental signals. Treatment of human fibroblasts with the Nrf2 activator sulforaphane causes an increase in mitochondrial mass and induction of PGC1α and PGC1β [92], although the potential dependence on Nrf2 was not examined in this study. However, diabetic mice in which Nrf2 is either activated by Keap1 gene hypomorphic knockdown (db/db:Keap1flox/−:Nrf2+/+) or disrupted (db/db:Keap1flox/−:Nrf2−/−) have lower hepatic PGC1α expression levels than control animals (db/db:Keap1flox/+:Nrf2+/+) [93]. No differences in the mRNA levels for PGC1α are seen in livers of nondiabetic mice that are either WT or Nrf2-KO, whereas these levels are lower in Nrf2-overexpressing (Keap1-KD and liver-specific Keap1-KO) animals [82]. Notably, a 24-h fast increases the levels of PGC1α mRNA in the livers of mice of all genotypes, but the increase is significantly greater in livers of Nrf2-KO compared to WT or Nrf2-overexpressing mice. Compared to WT, Nrf2-KO mice experiencing septic infection or acute lung injury due to infection show attenuated transcriptional upregulation of nuclear respiratory factor 1 and PGC1α [94], [95]. Together, these observations suggest that the role of Nrf2 in maintaining the levels of both nuclear respiratory factor 1 and PGC1α is complex and becomes most prominent under conditions of stress.

In addition to expression of genes encoding mitochondrial proteins, mitochondrial biogenesis requires the synthesis of nucleotides. Genetic activation of Nrf2 enhances purine biosynthesis by upregulating the pentose phosphate pathway and the metabolism of folate and glutamine, particularly in rapidly proliferating cells (Fig. 2) [24]. Analysis of the transcriptome of mutant Drosophila deficient for the mitochondrial serine/threonine protein kinase PTEN-induced putative kinase 1 (PINK1) has shown that mitochondrial dysfunction leads to the transcriptional upregulation of genes affecting nucleotide metabolism [96], suggesting that the enhanced nucleotide biosynthesis represents a mechanism for protection against the neurotoxic consequences of PINK1 deficiency. Nrf2 regulates the expression of phosphoribosyl pyrophosphate amidotransferase (PPAT), which catalyzes the entry into the de novo purine nucleotide biosynthetic pathway, and mitochondrial methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) (Fig. 2). The latter is a bifunctional enzyme with dehydrogenase and cyclohydrolase activities that is critical in providing both glycine and formate as sources of one-carbon units for purine biosynthesis in rapidly growing cells [97]. It is therefore likely that Nrf2 activation might be protective and might reverse mitochondrial dysfunction in PINK1 deficiency. Indeed, pharmacological activation of Nrf2 by sulforaphane, or the triterpenoid RTA-408, restores ∆ψm and protects PINK1-deficient cells against dopamine toxicity [98]. Although the underlying mechanisms seem to be complex, together, these findings indicate that Nrf2 activity may affect mitochondrial biogenesis by influencing the expression levels of critical transcription factors and coactivators, as well as by enhancing nucleotide biosynthesis.

Nrf2 and Mitochondrial Integrity

Although direct evidence is not always available, there are strong indications that Nrf2 is important for mitochondrial integrity, particularly under conditions of oxidative stress. Mitochondria isolated from the brain and liver of rats that had been administered a single dose of the Nrf2 activator sulforaphane are resistant to opening of the mitochondrial permeability transition pore (mPTP) caused by the oxidant tert-butylhydroperoxide [99], [100]. The mPTP, a complex that allows the mitochondrial inner membrane to become permeable to molecules with masses up to 1500 Da, was recently identified to be formed from dimers of the F0F1-ATP synthase [101]. The sulforaphane-mediated resistance to mPTP opening correlates with increased antioxidant defenses, and the levels of mitochondrial GSH, glutathione peroxidase 1, malic enzyme 3, and thioredoxin 2 are all upregulated in mitochondrial fractions isolated from sulforaphane-treated animals [100].

Mitochondrial protein damage and impairment in respiration caused by the electrophilic lipid peroxidation product 4-hydroxy-2-nonenal are attenuated in mitochondria isolated from the cerebral cortex of sulforaphane-treated mice [102]. In rat renal epithelial cells and in kidney, sulforaphane is protective against cisplatin- and gentamicin-induced toxicity and loss of ∆ψm[103], [104]. Protection against a panel of oxidants (superoxide, hydrogen peroxide, peroxynitrite) and electrophiles (4-hydroxy-2-nonenal and acrolein) and an increase in mitochondrial antioxidant defenses have been also observed upon treatment of rat aortic smooth muscle cells with sulforaphane [105]. In a model of contrast-induced acute kidney injury, limb ischemic preconditioning was recently shown to have protective effects, including inhibition of the opening of the mPTP and mitochondrial swelling, by activation of Nrf2 consequent to the inhibition of GSK3β [106].

Mitophagy, the process by which dysfunctional mitochondria are selectively engulfed by autophagosomes and delivered to lysosomes to be degraded and recycled by the cell, is essential for mitochondrial homeostasis [107], [108]. Whereas no causative relation between Nrf2 and mitophagy has been established, there is evidence that the transcription factor may be important in mitochondrial quality control by playing a role in mitophagy. This might be especially prominent under conditions of oxidative stress. Thus, in a model of sepsis, the increases in the levels of the autophagosome marker MAP1 light chain 3-II (LC3-II) and the cargo protein p62 at 24 h postinfection are suppressed in Nrf2-KO compared to WT mice [109]. A small-molecule inducer of mitophagy (called p62-mediated mitophagy inducer, PMI) was recently discovered; this 1,4-diphenyl-1,2,3-triazole compound was originally designed as an Nrf2 activator that disrupts the interaction of the transcription factor with Keap1 [110]. Similar to cells in which Nrf2 is genetically upregulated (Keap1-KD or Keap1-KO), cells exposed to PMI have higher resting Δψm. Importantly, the increase in mitochondrial LC3 localization that is observed after PMI treatment of WT cells does not occur in Nrf2-KO cells, suggesting the involvement of Nrf2.

Last, ultrastructural analysis of liver sections has revealed the presence of swollen mitochondria with reduced crista and disrupted membranes in hepatocytes of Nrf2-KO, but not WT, mice that had been fed a high-fat diet for 24 weeks; notably, these livers show clear evidence of oxidative stress and inflammation [68]. It can be concluded that Nrf2 has a critical role in maintaining mitochondrial integrity under conditions of oxidative and inflammatory stress.

Sulforaphane and Its Effects on Cancer, Mortality, Aging, Brain and Behavior, Heart Disease & More

Isothiocyanates are some of the most important plant compounds you can get in your diet. In this video I make the most comprehensive case for them that has ever been made. Short attention span? Skip to your favorite topic by clicking one of the time points below. Full timeline below.

Key sections:

  • 00:01:14 – Cancer and mortality
  • 00:19:04 – Aging
  • 00:26:30 – Brain and behavior
  • 00:38:06 – Final recap
  • 00:40:27 – Dose

Full timeline:

  • 00:00:34 – Introduction of sulforaphane, a major focus of the video.
  • 00:01:14 – Cruciferous vegetable consumption and reductions in all-cause mortality.
  • 00:02:12 – Prostate cancer risk.
  • 00:02:23 – Bladder cancer risk.
  • 00:02:34 – Lung cancer in smokers risk.
  • 00:02:48 – Breast cancer risk.
  • 00:03:13 – Hypothetical: what if you already have cancer? (interventional)
  • 00:03:35 – Plausible mechanism driving the cancer and mortality associative data.
  • 00:04:38 – Sulforaphane and cancer.
  • 00:05:32 – Animal evidence showing strong effect of broccoli sprout extract on bladder tumor development in rats.
  • 00:06:06 – Effect of direct supplementation of sulforaphane in prostate cancer patients.
  • 00:07:09 – Bioaccumulation of isothiocyanate metabolites in actual breast tissue.
  • 00:08:32 – Inhibition of breast cancer stem cells.
  • 00:08:53 – History lesson: brassicas were established as having health properties even in ancient Rome.
  • 00:09:16 – Sulforaphane’s ability to enhance carcinogen excretion (benzene, acrolein).
  • 00:09:51 – NRF2 as a genetic switch via antioxidant response elements.
  • 00:10:10 – How NRF2 activation enhances carcinogen excretion via glutathione-S-conjugates.
  • 00:10:34 – Brussels sprouts increase glutathione-S-transferase and reduce DNA damage.
  • 00:11:20 – Broccoli sprout drink increases benzene excretion by 61%.
  • 00:13:31 – Broccoli sprout homogenate increases antioxidant enzymes in the upper airway.
  • 00:15:45 – Cruciferous vegetable consumption and heart disease mortality.
  • 00:16:55 – Broccoli sprout powder improves blood lipids and overall heart disease risk in type 2 diabetics.
  • 00:19:04 – Beginning of aging section.
  • 00:19:21 – Sulforaphane-enriched diet enhances lifespan of beetles from 15 to 30% (in certain conditions).
  • 00:20:34 – Importance of low inflammation for longevity.
  • 00:22:05 – Cruciferous vegetables and broccoli sprout powder seem to reduce a wide variety of inflammatory markers in humans.
  • 00:23:40 – Mid-video recap: cancer, aging sections
  • 00:24:14 – Mouse studies suggest sulforaphane might improve adaptive immune function in old age.
  • 00:25:18 – Sulforaphane improved hair growth in a mouse model of balding. Picture at 00:26:10.
  • 00:26:30 – Beginning of brain and behavior section.
  • 00:27:18 – Effect of broccoli sprout extract on autism.
  • 00:27:48 – Effect of glucoraphanin on schizophrenia.
  • 00:28:17 – Start of depression discussion (plausible mechanism and studies).
  • 00:31:21 – Mouse study using 10 different models of stress-induced depression show sulforaphane similarly effective as fluoxetine (prozac).
  • 00:32:00 – Study shows direct ingestion of glucoraphanin in mice is similarly effective at preventing depression from social defeat stress model.
  • 00:33:01 – Beginning of neurodegeneration section.
  • 00:33:30 – Sulforaphane and Alzheimer’s disease.
  • 00:33:44 – Sulforaphane and Parkinson’s disease.
  • 00:33:51 – Sulforaphane and Hungtington’s disease.
  • 00:34:13 – Sulforaphane increases heat shock proteins.
  • 00:34:43 – Beginning of traumatic brain injury section.
  • 00:35:01 – Sulforaphane injected immediately after TBI improves memory (mouse study).
  • 00:35:55 – Sulforaphane and neuronal plasticity.
  • 00:36:32 – Sulforaphane improves learning in model of type II diabetes in mice.
  • 00:37:19 – Sulforaphane and duchenne muscular dystrophy.
  • 00:37:44 – Myostatin inhibition in muscle satellite cells (in vitro).
  • 00:38:06 – Late-video recap: mortality and cancer, DNA damage, oxidative stress and inflammation, benzene excretion, cardiovascular disease, type II diabetes, effects on the brain (depression, autism, schizophrenia, neurodegeneration), NRF2 pathway.
  • 00:40:27 – Thoughts on figuring out a dose of broccoli sprouts or sulforaphane.
  • 00:41:01 – Anecdotes on sprouting at home.
  • 00:43:14 – On cooking temperatures and sulforaphane activity.
  • 00:43:45 – Gut bacteria conversion of sulforaphane from glucoraphanin.
  • 00:44:24 – Supplements work better when combined with active myrosinase from vegetables.
  • 00:44:56 – Cooking techniques and cruciferous vegetables.
  • 00:46:06 – Isothiocyanates as goitrogens.
Dr Jimenez White Coat

Nrf2 is a transcription factor which plays an important role in the cellular antioxidant defense system of the human body. The antioxidant responsive element, or ARE, is a regulatory mechanism of genes. Many research studies have demonstrated that Nrf2, or NF-E2-related factor 2, regulates a wide variety of ARE-driven genes throughout several types of cells. Nrf2 was also found to play an essential role in cellular protection and anti-carcinogenicity, which demonstrates that Nrf2 may be an effective treatment in the management of neurodegenerative diseases and cancers believed to be caused by oxidative stress.

Dr. Alex Jimenez D.C., C.C.S.T. Insight

Concluding Remarks

Although many questions still remain open, the available experimental evidence clearly indicates that Nrf2 is an important player in the maintenance of mitochondrial homeostasis and structural integrity. This role becomes particularly critical under conditions of oxidative, electrophilic, and inflammatory stress when the ability to upregulate Nrf2-mediated cytoprotective responses influences the overall health and survival of the cell and the organism. The role of Nrf2 in mitochondrial function represents another layer of the broad cytoprotective mechanisms orchestrated by this transcription factor. As many human pathological conditions have oxidative stress, inflammation, and mitochondrial dysfunction as essential components of their pathogenesis, pharmacological activation of Nrf2 holds promise for disease prevention and treatment. Comprehensive understanding of the precise mechanisms by which Nrf2 affects mitochondrial function is essential for rational design of future clinical trials and may offer new biomarkers for monitoring therapeutic efficacy.

Acknowledgments

Sciencedirect.com/science/article/pii/S0891584915002129

The purpose of the article above was to discuss as well as demonstrate the emerging role of Nrf2 in mitochondrial function. Nrf2, or nuclear factor erythroid 2-related factor, is an emerging regulator of cellular resistance to oxidants which can contribute to oxidative stress, affecting cellular function and leading to the development of toxicity, chronic disease, and even cancer. While the production of oxidants in the human body can serve various purposes, including cell division, inflammation, immune function, autophagy, and stress response, it’s essential to control their overproduction to prevent health issues. The scope of our information is limited to chiropractic and spinal health issues. To discuss the subject matter, please feel free to ask Dr. Jimenez or contact us at 915-850-0900 .

Curated by Dr. Alex Jimenez

Referenced from: Sciencedirect.com

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Additional Topic Discussion: Acute Back Pain

Back pain is one of the most prevalent causes of disability and missed days at work worldwide. Back pain attributes to the second most common reason for doctor office visits, outnumbered only by upper-respiratory infections. Approximately 80 percent of the population will experience back pain at least once throughout their life. The spine is a complex structure made up of bones, joints, ligaments, and muscles, among other soft tissues. Because of this, injuries and/or aggravated conditions, such as herniated discs, can eventually lead to symptoms of back pain. Sports injuries or automobile accident injuries are often the most frequent cause of back pain, however, sometimes the simplest of movements can have painful results. Fortunately, alternative treatment options, such as chiropractic care, can help ease back pain through the use of spinal adjustments and manual manipulations, ultimately improving pain relief.

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EXTRA EXTRA | IMPORTANT TOPIC: Recommended El Paso, TX Chiropractor

***

Post Disclaimer

Professional Scope of Practice *

The information herein on "The Emerging Role Of Nrf2 In Mitochondrial Function" is not intended to replace a one-on-one relationship with a qualified health care professional or licensed physician and is not medical advice. We encourage you to make healthcare decisions based on your research and partnership with a qualified healthcare professional.

Blog Information & Scope Discussions

Our information scope is limited to Chiropractic, musculoskeletal, physical medicines, wellness, contributing etiological viscerosomatic disturbances within clinical presentations, associated somatovisceral reflex clinical dynamics, subluxation complexes, sensitive health issues, and/or functional medicine articles, topics, and discussions.

We provide and present clinical collaboration with specialists from various disciplines. Each specialist is governed by their professional scope of practice and their jurisdiction of licensure. We use functional health & wellness protocols to treat and support care for the injuries or disorders of the musculoskeletal system.

Our videos, posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate to and directly or indirectly support our clinical scope of practice.*

Our office has reasonably attempted to provide supportive citations and has identified the relevant research study or studies supporting our posts. We provide copies of supporting research studies available to regulatory boards and the public upon request.

We understand that we cover matters that require an additional explanation of how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez, DC, or contact us at 915-850-0900.

We are here to help you and your family.

Blessings

Dr. Alex Jimenez DC, MSACP, RN*, CCST, IFMCP*, CIFM*, ATN*

email: coach@elpasofunctionalmedicine.com

Licensed as a Doctor of Chiropractic (DC) in Texas & New Mexico*
Texas DC License # TX5807, New Mexico DC License # NM-DC2182

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Injury & Functional Fitness Rehabiliation Center: Taking Functional Recovery To A New Level - No Matter Age or Impairment.
PODCAST: Ryan Welage and Alexander Jimenez, both medical students at the National University of Health Sciences, discuss the several new approaches that they developed in order to help people continue to engage and participate in exercise from the comfort of their own homes. Using their advanced understanding of functional medicine, biomechanics, and nutrition, they undertake explaining simple methods and techniques for complex movement protocols. Moreover, Alexander Jimenez and Ryan Welage discuss how diet can be an essential element in overall health and wellness. Dr. Alex Jimenez offers additional guidelines with the Functional Fitness Fellas, among further advice. - Podcast Insight

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The Functional Fitness Fellas | What is it? & Who Are They?

Dr. Alexander Jimenez 103 views May 17, 2020 2:46 pm

PODCAST: Dr. Alex Jimenez, a chiropractor in El Paso, TX, Kenna Vaughn, and Astrid Ornelas discuss a variety of natural treatment methods and techniques in treating inflammation as the primary focus of this podcast video. Dr. Alex Jimenez, Kenna Vaughn, and Astrid Ornelas present a discussion of natural ways to treat inflammatory cascades, including nutrition, diet, and nutraceuticals, among others. Knowing what are the best supplements are also presented as the primary focus of this podcast video. Nutraceuticals are considered to be a safe and effective alternative treatment approach that is well researched by scientists to help promote health and wellness. - Podcast Insight

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PODCAST: Dr. Alex Jimenez, a chiropractor in El Paso, TX, Kenna Vaughn, and Astrid Ornelas discuss a variety of natural treatment methods and techniques in treating inflammation as the primary focus of this podcast video. Dr. Alex Jimenez, Kenna Vaughn, and Astrid Ornelas present a discussion of natural ways to treat inflammatory cascades, including nutrition, diet, and nutraceuticals, among others. Knowing what are the best supplements are also presented as the primary focus of this podcast video. Nutraceuticals are considered to be a safe and effective alternative treatment approach that is well researched by scientists to help promote health and wellness. - Podcast Insight

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Treating Inflammation Naturally | El Paso, Tx (2020)

Dr. Alexander Jimenez 165 views April 3, 2020 8:27 pm

Chronic back pain is a well-known health issue which unfortunately commonly affects many people throughout their lifetime. From chronic neck pain and back pain to widespread chronic pain symptoms associated with fibromyalgia, these painful symptoms can ultimately affect an individual's overall health and wellness as well as their quality of life. Dr. Alex Jimenez is a chiropractor, or doctor of chiropractic (DC), who focuses on the diagnosis, treatment, and prevention of a variety of health issues, including chronic pain. Patients tell their stories and describe how Dr. Alex Jimenez has helped them recover their overall quality of life as well as their health and wellness. The patients highly recommend Dr. Alex Jimenez as the non-surgical choice for chronic pain, among other health issues.  

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Chronic back pain is a well-known health issue which unfortunately commonly affects many people throughout their lifetime. From chronic neck pain and back pain to widespread chronic pain symptoms associated with fibromyalgia, these painful symptoms can ultimately affect an individual's overall health and wellness as well as their quality of life. Dr. Alex Jimenez is a chiropractor, or doctor of chiropractic (DC), who focuses on the diagnosis, treatment, and prevention of a variety of health issues, including chronic pain. Patients tell their stories and describe how Dr. Alex Jimenez has helped them recover their overall quality of life as well as their health and wellness. The patients highly recommend Dr. Alex Jimenez as the non-surgical choice for chronic pain, among other health issues.

If you have enjoyed this video and/or we have helped you in any way
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Thank You & God Bless.
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Chronic *BACK PAIN* Therapy | El Paso, Tx (2019)

Dr. Alexander Jimenez 66 views June 14, 2019 4:51 pm

Sciatica, or sciatic nerve pain, is a common health issue which can affect approximately 8 out of 10 people throughout their lifetimes. Patients describe how their back pain affected their ability to engage in their everyday physical activities. Truide Torres discusses how she struggled with back pain during her pregnancy. Dionicio Espinoza discusses how his job as a truck driver can trigger his back pain. Patients recommend chiropractic care with Dr. Alex Jimenez, DC, in El Paso, TX, to treat sciatica, or sciatic nerve pain, and back pain.

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Sciatica, or sciatic nerve pain, is a common health issue which can affect approximately 8 out of 10 people throughout their lifetimes. Patients describe how their back pain affected their ability to engage in their everyday physical activities. Truide Torres discusses how she struggled with back pain during her pregnancy. Dionicio Espinoza discusses how his job as a truck driver can trigger his back pain. Patients recommend chiropractic care with Dr. Alex Jimenez, DC, in El Paso, TX, to treat sciatica, or sciatic nerve pain, and back pain.

If you have enjoyed this video and/or we have helped you in any way
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Thank You & God Bless.
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Facebook Sports Page: https://www.facebook.com/pushasrx/
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Facebook Fitness Center Page: https://www.facebook.com/PUSHftinessathletictraining/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information:
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Rehabilitation Center: https://www.pushasrx.com
Functional Medicine: https://wellnessdoctorrx.com
Fitness & Nutrition: http://www.push4fitness.com/team/

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

0 0

YouTube Video UEwzeUg1RlctbFNNT2Fac3o4VGxxUE9rZW1PTUJYNUxxLS5CQkEwRDA0MDkwNUM2MDY1

The *SCIATICA* Specialist | El Paso, Tx (2019)

Dr. Alexander Jimenez 240 views May 24, 2019 4:56 pm

April Hermosillo achieves overall health and wellness every day by following proper nutrition and engaging in exercises or physical activities. As a regular fitness participant, however, April Hermosillo can experience back and low back pain which ultimately affects even her most basic daily tasks. April Hermosillo struggled with spine health issues and sciatica before she received chiropractic care. Dr. Alex Jimenez is a chiropractor in El Paso, TX who has helped April Hermosillo achieve pain relief so she can return to her everyday fitness routines. April Hermosillo describes how Dr. Alex Jimenez has tremendously helped improve her overall symptoms. April Hermosillo highly recommends Dr. Alex Jimenez as the non-surgical choice for personalized spine and sciatica treatment and rehabilitation.

If you have enjoyed this video and/or we have helped you in any way 
please feel free to subscribe and share us. 

Thank You & God Bless.   
Dr. Alex Jimenez DC, MSACP, ATN, IFMCP. CIFM, CCST

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Sports Page: https://www.facebook.com/pushasrx/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/
Facebook Fitness Center Page: https://www.facebook.com/justplayfitness

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: 
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Rehabilitation Center: https://www.pushasrx.com
Functional Medicine: https://wellnessdoctorrx.com
- 

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

April Hermosillo achieves overall health and wellness every day by following proper nutrition and engaging in exercises or physical activities. As a regular fitness participant, however, April Hermosillo can experience back and low back pain which ultimately affects even her most basic daily tasks. April Hermosillo struggled with spine health issues and sciatica before she received chiropractic care. Dr. Alex Jimenez is a chiropractor in El Paso, TX who has helped April Hermosillo achieve pain relief so she can return to her everyday fitness routines. April Hermosillo describes how Dr. Alex Jimenez has tremendously helped improve her overall symptoms. April Hermosillo highly recommends Dr. Alex Jimenez as the non-surgical choice for personalized spine and sciatica treatment and rehabilitation.

If you have enjoyed this video and/or we have helped you in any way
please feel free to subscribe and share us.

Thank You & God Bless.
Dr. Alex Jimenez RN, DC, MSACP, CCST

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Sports Page: https://www.facebook.com/pushasrx/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/
Facebook Fitness Center Page: https://www.facebook.com/PUSHftinessathletictraining/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information:
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Rehabilitation Center: https://www.pushasrx.com
Functional Medicine: https://wellnessdoctorrx.com
Fitness & Nutrition: http://www.push4fitness.com/team/

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

1 0

YouTube Video UEwzeUg1RlctbFNNT2Fac3o4VGxxUE9rZW1PTUJYNUxxLS42Qzk5MkEzQjVFQjYwRDA4

Personalized *SPINE & SCIATICA* Treatment | El Paso, Tx (2019)

Dr. Alexander Jimenez 114 views March 29, 2019 1:21 pm

Sciatica is a collection of symptoms characterized by pain which extends down the length of the legs from the lower back. Approximately 90 percent of sciatica, or sciatic nerve pain, develops when a spinal disc herniation compresses a spinal nerve along the lumbar spine. Piriformis syndrome and pregnancy are other common causes of sciatica. Chiropractic care is an alternative, treatment option which focuses on the treatment of injuries and/or conditions associated with the musculoskeletal and nervous system. Patients describe how Dr. Alex Jimenez has helped them achieve sciatica relief through chiropractic care. Edgar M. Reyes and Truide Torres highly recommend Dr. Alex Jimenez as the non-surgical choice for sciatica.

If you have enjoyed this video and/or we have helped you in any way please feel free to subscribe and share us.  

Thank You & God Bless.    
Dr. Alex Jimenez DC, MSACP, ATN, IFMCP. CIFM, CCST 

Subscribe: http://bit.ly/drjyt 

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/ 
Facebook Sports Page: https://www.facebook.com/pushasrx/ 
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/ 
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/ 
Facebook Fitness Center Page: https://www.facebook.com/justplayfitness 

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2 
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ 

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/ 

Information:  
Clinical Site: https://www.dralexjimenez.com 
Injury Site: https://personalinjurydoctorgroup.com 
Sports Injury Site: https://chiropracticscientist.com 
Back Injury Site: https://www.elpasobackclinic.com 
Rehabilitation Center: https://www.pushasrx.com 
Functional Medicine: https://wellnessdoctorrx.com 
-  

Twitter: https://twitter.com/dralexjimenez 
Twitter: https://twitter.com/crossfitdoctor

Sciatica is a collection of symptoms characterized by pain which extends down the length of the legs from the lower back. Approximately 90 percent of sciatica, or sciatic nerve pain, develops when a spinal disc herniation compresses a spinal nerve along the lumbar spine. Piriformis syndrome and pregnancy are other common causes of sciatica. Chiropractic care is an alternative, treatment option which focuses on the treatment of injuries and/or conditions associated with the musculoskeletal and nervous system. Patients describe how Dr. Alex Jimenez has helped them achieve sciatica relief through chiropractic care. Edgar M. Reyes and Truide Torres highly recommend Dr. Alex Jimenez as the non-surgical choice for sciatica.

If you have enjoyed this video and/or we have helped you in any way please feel free to subscribe and share us.

Thank You & God Bless.
Dr. Alex Jimenez RN, DC, MSACP, CCST

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Sports Page: https://www.facebook.com/pushasrx/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/
Facebook Fitness Center Page: https://www.facebook.com/PUSHftinessathletictraining/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information:
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Rehabilitation Center: https://www.pushasrx.com
Functional Medicine: https://wellnessdoctorrx.com
Fitness & Nutrition: http://www.push4fitness.com/team/

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

0 0

YouTube Video UEwzeUg1RlctbFNNT2Fac3o4VGxxUE9rZW1PTUJYNUxxLS4zMEQ1MEIyRTFGNzhDQzFB

Advanced Sciatica Treatment | El Paso, Tx (Chiropractor)

Dr. Alexander Jimenez 41 views March 22, 2019 4:17 pm

Truide Torres recibe atención quiropráctica con el Dr. Alex Jimenez por su dolor en el nervio ciático. La ciática es una colección de síntomas caracterizados por dolor lumbar que se irradia a través de los muslos hacia las piernas, rodillas y pies. El dolor del nervio ciático puede afectar uno o ambos lados de las extremidades inferiores. Truide Torres luchó para participar en sus actividades físicas diarias debido a sus síntomas de ciática. A través de ajustes espinales y manipulaciones manuales, el Dr. Alex Jimenez restauró cuidadosamente la alineación original de su columna, aliviando sus síntomas dolorosos. Truide Torres recomienda al Dr. Alex Jimenez y su personal como la opción no quirúrgica para la ciática.

Recomiéndanos: Si te ha gustado este video y / o te hemos ayudado de alguna manera, no dudes en recomendarnos. Gracias, Dios te bendiga.

Recommend: Dr. Alex Jimenez – Chiropractor 
Health Grades: http://www.healthgrades.com/review/3SDJ4 
Facebook Clinical Page: https://www.facebook.com/dralexjimenez/reviews/ 
Facebook Sports Page: https://www.facebook.com/pushasrx/ 
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/ 
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/ 
Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2 
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ 

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/ 

Information: Dr. Alex Jimenez – Chiropractor 
Clinical Site: https://www.dralexjimenez.com 
Injury Site: https://personalinjurydoctorgroup.com 
Sports Injury Site: https://chiropracticscientist.com 
Back Injury Site: https://www.elpasobackclinic.com 

Pinterest: https://www.pinterest.com/dralexjimenez/ 
Twitter: https://twitter.com/dralexjimenez 
Twitter: https://twitter.com/crossfitdoctor 

Recommend: PUSH-as-Rx ®™ 
Rehabilitation Center: https://www.pushasrx.com 
Facebook: https://www.facebook.com/justplayfitness 
PUSH-as-Rx: www.pushasrx.com

Truide Torres recibe atención quiropráctica con el Dr. Alex Jimenez por su dolor en el nervio ciático. La ciática es una colección de síntomas caracterizados por dolor lumbar que se irradia a través de los muslos hacia las piernas, rodillas y pies. El dolor del nervio ciático puede afectar uno o ambos lados de las extremidades inferiores. Truide Torres luchó para participar en sus actividades físicas diarias debido a sus síntomas de ciática. A través de ajustes espinales y manipulaciones manuales, el Dr. Alex Jimenez restauró cuidadosamente la alineación original de su columna, aliviando sus síntomas dolorosos. Truide Torres recomienda al Dr. Alex Jimenez y su personal como la opción no quirúrgica para la ciática.

Recomiéndanos: Si te ha gustado este video y / o te hemos ayudado de alguna manera, no dudes en recomendarnos. Gracias, Dios te bendiga.

Recommend: Dr. Alex Jimenez – Chiropractor
Health Grades: http://www.healthgrades.com/review/3SDJ4
Facebook Clinical Page: https://www.facebook.com/dralexjimenez/reviews/
Facebook Sports Page: https://www.facebook.com/pushasrx/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/
Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: Dr. Alex Jimenez – Chiropractor
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com

Pinterest: https://www.pinterest.com/dralexjimenez/
Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

Recommend: PUSH-as-Rx ®™
Rehabilitation Center: https://www.pushasrx.com
Facebook: https://www.facebook.com/PUSHftinessathletictraining/
PUSH-as-Rx: http://www.push4fitness.com/team/

0 0

YouTube Video UEwzeUg1RlctbFNNT2Fac3o4VGxxUE9rZW1PTUJYNUxxLS40QzRDOEU0QUYwNUIxN0M1

Tratamiendo para dolor de nervio Ciático | El Paso, Tx

Dr. Alexander Jimenez 93 views December 17, 2018 12:44 pm

Sciatica is a collection of symptoms characterized by pain, discomfort, tingling and burning sensations, and numbness which often extends from the low back, down the buttocks and thighs, into the knee and the foot. Sciatica is caused by the compression of the sciatic nerve, the largest and longest nerve in the human body. Sciatic nerve pain can develop due to an injury and/or aggravated condition. Patients diagnosed with sciatica describe their symptoms and how these affected their daily lives. Dr. Alex Jimenez and his staff have provided pain relief to many patients experiencing sciatica. Chiropractic care can help restore the original alignment of the spine to help improve sciatica. Dr. Alex Jimenez is the non-surgical choice for a variety of health issues, including sciatica, or sciatic nerve pain.

Please Recommend Us: If you have enjoyed this video and/or we have helped you in any way please feel free to recommend us. Thank You & God Bless.  

Recommend: Dr. Alex Jimenez – Chiropractor 
Health Grades: http://www.healthgrades.com/review/3SDJ4 
Facebook Clinical Page: https://www.facebook.com/dralexjimenez/reviews/ 
Facebook Sports Page: https://www.facebook.com/pushasrx/ 
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/ 
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/ 
Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2 
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ 

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/ 

Information: Dr. Alex Jimenez – Chiropractor 
Clinical Site: https://www.dralexjimenez.com 
Injury Site: https://personalinjurydoctorgroup.com 
Sports Injury Site: https://chiropracticscientist.com 
Back Injury Site: https://www.elpasobackclinic.com 

Pinterest: https://www.pinterest.com/dralexjimenez/ 
Twitter: https://twitter.com/dralexjimenez 
Twitter: https://twitter.com/crossfitdoctor 

Recommend: PUSH-as-Rx ®™ 
Rehabilitation Center: https://www.pushasrx.com 
Facebook: https://www.facebook.com/justplayfitness 
PUSH-as-Rx: www.pushasrx.com

Sciatica is a collection of symptoms characterized by pain, discomfort, tingling and burning sensations, and numbness which often extends from the low back, down the buttocks and thighs, into the knee and the foot. Sciatica is caused by the compression of the sciatic nerve, the largest and longest nerve in the human body. Sciatic nerve pain can develop due to an injury and/or aggravated condition. Patients diagnosed with sciatica describe their symptoms and how these affected their daily lives. Dr. Alex Jimenez and his staff have provided pain relief to many patients experiencing sciatica. Chiropractic care can help restore the original alignment of the spine to help improve sciatica. Dr. Alex Jimenez is the non-surgical choice for a variety of health issues, including sciatica, or sciatic nerve pain.

Please Recommend Us: If you have enjoyed this video and/or we have helped you in any way please feel free to recommend us. Thank You & God Bless.

Recommend: Dr. Alex Jimenez – Chiropractor
Health Grades: http://www.healthgrades.com/review/3SDJ4
Facebook Clinical Page: https://www.facebook.com/dralexjimenez/reviews/
Facebook Sports Page: https://www.facebook.com/pushasrx/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/
Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: Dr. Alex Jimenez – Chiropractor
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com

Pinterest: https://www.pinterest.com/dralexjimenez/
Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

Recommend: PUSH-as-Rx ®™
Rehabilitation Center: https://www.pushasrx.com
Facebook: https://www.facebook.com/PUSHftinessathletictraining/
PUSH-as-Rx: http://www.push4fitness.com/team/

0 0

YouTube Video UEwzeUg1RlctbFNNT2Fac3o4VGxxUE9rZW1PTUJYNUxxLS5DNkMwRUI2MkI4QkI4NDFG

Rehabilitation for Sciatica Pain | El Paso, Tx.

Dr. Alexander Jimenez 42 views November 30, 2018 5:33 pm

A common health issue frequently treated by Dr. Alex Jimenez, sciatica is a collection of symptoms caused by the compression or impingement of the sciatic nerve, the largest and longest nerve in the human body. The most common symptoms of sciatica include low back pain, hip pain, and radiating pain which extends from the buttocks down into the feet. Dr. Alex Jimenez and his staff have helped many patients achieve pain relief from their sciatica symptoms through the use of a variety of treatment methods and techniques, educating them about their health issues. Dr. Alex Jimenez is the non-surgical choice for sciatic nerve pain. 

Please Recommend Us: If you have enjoyed this video and/or we have helped you in any way please feel free to recommend us. Thank You & God Bless.  

Recommend: Dr. Alex Jimenez – Chiropractor 
Health Grades: http://www.healthgrades.com/review/3SDJ4 
Facebook Clinical Page: https://www.facebook.com/dralexjimenez/reviews/ 
Facebook Sports Page: https://www.facebook.com/pushasrx/ 
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/ 
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/ 
Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2 
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ 

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/ 

Information: Dr. Alex Jimenez – Chiropractor 
Clinical Site: https://www.dralexjimenez.com 
Injury Site: https://personalinjurydoctorgroup.com 
Sports Injury Site: https://chiropracticscientist.com 
Back Injury Site: https://www.elpasobackclinic.com 

Pinterest: https://www.pinterest.com/dralexjimenez/ 
Twitter: https://twitter.com/dralexjimenez 
Twitter: https://twitter.com/crossfitdoctor 

Recommend: PUSH-as-Rx ®™ 
Rehabilitation Center: https://www.pushasrx.com 
Facebook: https://www.facebook.com/justplayfitness 
PUSH-as-Rx: www.pushasrx.com

A common health issue frequently treated by Dr. Alex Jimenez, sciatica is a collection of symptoms caused by the compression or impingement of the sciatic nerve, the largest and longest nerve in the human body. The most common symptoms of sciatica include low back pain, hip pain, and radiating pain which extends from the buttocks down into the feet. Dr. Alex Jimenez and his staff have helped many patients achieve pain relief from their sciatica symptoms through the use of a variety of treatment methods and techniques, educating them about their health issues. Dr. Alex Jimenez is the non-surgical choice for sciatic nerve pain.

Please Recommend Us: If you have enjoyed this video and/or we have helped you in any way please feel free to recommend us. Thank You & God Bless.

Recommend: Dr. Alex Jimenez – Chiropractor
Health Grades: http://www.healthgrades.com/review/3SDJ4
Facebook Clinical Page: https://www.facebook.com/dralexjimenez/reviews/
Facebook Sports Page: https://www.facebook.com/pushasrx/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/
Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: Dr. Alex Jimenez – Chiropractor
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com

Pinterest: https://www.pinterest.com/dralexjimenez/
Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

Recommend: PUSH-as-Rx ®™
Rehabilitation Center: https://www.pushasrx.com
Facebook: https://www.facebook.com/PUSHftinessathletictraining/
PUSH-as-Rx: http://www.push4fitness.com/team/

0 0

YouTube Video UEwzeUg1RlctbFNNT2Fac3o4VGxxUE9rZW1PTUJYNUxxLS4zQzFBN0RGNzNFREFCMjBE

Education About Sciatica | El Paso, Tx

Dr. Alexander Jimenez 85 views November 21, 2018 5:44 pm

Discover the repercussions of overlooking injuries in this eye-opening video. From ankle sprains to severe accidents, witness the unseen consequences that affect the body's dynamics. Join us as we delve into the interconnectedness of pain and explore why prompt assessment and treatment are crucial for true healing.

We present, bridge, and connect various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.     

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.     

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.     

It is all about.   

LIVING, LOVING & MATTERING     

Join us in improving your health.     

Blessings,     

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone: 
phone: 915-850-0900   

Licensed in Texas & New Mexico*         

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.     

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.     

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.     
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*     

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: 
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com 

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

Discover the repercussions of overlooking injuries in this eye-opening video. From ankle sprains to severe accidents, witness the unseen consequences that affect the body's dynamics. Join us as we delve into the interconnectedness of pain and explore why prompt assessment and treatment are crucial for true healing.

We present, bridge, and connect various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.

It is all about.

LIVING, LOVING & MATTERING

Join us in improving your health.

Blessings,

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone:
phone: 915-850-0900

Licensed in Texas & New Mexico*

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information:
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

YouTube Video VVV5NTNGNC1RbUg3WVdEQ1NHUnF4T0VRLlBieXc1eUFXUWJz

Unlocking Wellness: The Consequences of Ignoring Care | El Paso, Tx (2024)

Dr. Alexander Jimenez views March 20, 2024 8:44 am

Today we discuss how chiropractic care can be a powerful tool in your personal injury rehabilitation journey.

We will talk about the benefits of chiropractic care for pain relief and mobility improvement.
How chiropractors work alongside other healthcare professionals for a holistic recovery plan.
Getting the most out of your chiropractic treatment after an injury, and more!

Get back to feeling your best, naturally!

Our discussions team includes Integrative Doctors, Functional Medicine Experts, Nutritionists, Health Coaches, Chiropractors, Physical Medicine Doctors, Therapists, and Exercise Performance Specialists.       
We provide clinical insights, treatment options, and methods to achieve clinically sound, specific measured goals.*     

Functional & Integrative Health Live Events *   
✅ Stress Hormones & Health 
✅ Gut Health, Inflammation & Auto-Immunity* 
✅ Musculoskeletal Rehabilitation
✅ Fibromyalgia & Inflammation 
✅ Diabetes & Autoimmunity* 
✅ Weight Loss 
✅ Body Composition Analysis
✅ Thyroid Dysfunction* 
✅ Autoimmune Disorder*
✅ Heart Disease & Inflammation*
✅ Agility & Mobility 
✅ Injury Recovery Programs 
✅ Complex Lower Back Pain Recovery Plans 
✅ Severe Sciatica Syndromes 
✅ Other Complex Health Challenges
✅ Neutraceutical Recommendations
✅ Advanced Translational Nutrigenomics*
✅ Nutrigenomics, Proteomics, Metabalomics
✅ Care Plans (Advanced Clinical Practice) 
 
We present, bridge, and connect these various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.     

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.     

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.     

It is all about.   

LIVING, LOVING & MATTERING     

Join us in improving your health.     

Blessings,     

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone: 
phone: 915-850-0900   

Licensed in Texas & New Mexico*         

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.     

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.     

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.     
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*     

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: 
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com 

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

Today we discuss how chiropractic care can be a powerful tool in your personal injury rehabilitation journey.

We will talk about the benefits of chiropractic care for pain relief and mobility improvement.
How chiropractors work alongside other healthcare professionals for a holistic recovery plan.
Getting the most out of your chiropractic treatment after an injury, and more!

Get back to feeling your best, naturally!

Our discussions team includes Integrative Doctors, Functional Medicine Experts, Nutritionists, Health Coaches, Chiropractors, Physical Medicine Doctors, Therapists, and Exercise Performance Specialists.
We provide clinical insights, treatment options, and methods to achieve clinically sound, specific measured goals.*

Functional & Integrative Health Live Events *
✅ Stress Hormones & Health
✅ Gut Health, Inflammation & Auto-Immunity*
✅ Musculoskeletal Rehabilitation
✅ Fibromyalgia & Inflammation
✅ Diabetes & Autoimmunity*
✅ Weight Loss
✅ Body Composition Analysis
✅ Thyroid Dysfunction*
✅ Autoimmune Disorder*
✅ Heart Disease & Inflammation*
✅ Agility & Mobility
✅ Injury Recovery Programs
✅ Complex Lower Back Pain Recovery Plans
✅ Severe Sciatica Syndromes
✅ Other Complex Health Challenges
✅ Neutraceutical Recommendations
✅ Advanced Translational Nutrigenomics*
✅ Nutrigenomics, Proteomics, Metabalomics
✅ Care Plans (Advanced Clinical Practice)

We present, bridge, and connect these various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.

It is all about.

LIVING, LOVING & MATTERING

Join us in improving your health.

Blessings,

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone:
phone: 915-850-0900

Licensed in Texas & New Mexico*

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information:
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

YouTube Video VVV5NTNGNC1RbUg3WVdEQ1NHUnF4T0VRLkpmZkpIUE9OQy00

Personal Injury Rehabilitation | El Paso, Tx (2024)

Dr. Alexander Jimenez views March 12, 2024 8:34 am

Explore the transformative power of movement as chiropractors unveil the art of healing through motion. Discover how gentle adjustments and therapeutic exercises pave the path to holistic wellness in this enlightening journey into the world of chiropractic care.

We present, bridge, and connect various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.     

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.     

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.     

It is all about.   

LIVING, LOVING & MATTERING     

Join us in improving your health.     

Blessings,     

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone: 
phone: 915-850-0900   

Licensed in Texas & New Mexico*         

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.     

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.     

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.     
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*     

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: 
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com 

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

Explore the transformative power of movement as chiropractors unveil the art of healing through motion. Discover how gentle adjustments and therapeutic exercises pave the path to holistic wellness in this enlightening journey into the world of chiropractic care.

We present, bridge, and connect various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.

It is all about.

LIVING, LOVING & MATTERING

Join us in improving your health.

Blessings,

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone:
phone: 915-850-0900

Licensed in Texas & New Mexico*

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information:
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

YouTube Video VVV5NTNGNC1RbUg3WVdEQ1NHUnF4T0VRLkdLUVJ5V3dWeXpV

Movement Medicine: Chiropractic Care | El Paso, Tx (2024)

Dr. Alexander Jimenez views March 10, 2024 1:27 pm

#alternativemedicine

Dr. Alexander Jimenez views February 29, 2024 5:05 pm

In this video, we delve into the holistic approach of chiropractors, seamlessly blending traditional techniques with modern integrative practices. Discover how chiropractors synergize their expertise with various medical disciplines, offering patients a comprehensive and personalized approach to wellness. From spinal adjustments to nutritional guidance, acupuncture, and mindfulness techniques, witness the transformative power of integrating chiropractic care into the broader spectrum of holistic healthcare.

We present, bridge, and connect various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.     

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.     

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.     

It is all about.   

LIVING, LOVING & MATTERING     

Join us in improving your health.     

Blessings,     

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone: 
phone: 915-850-0900   

Licensed in Texas & New Mexico*         

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.     

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.     

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.     
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*     

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: 
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com 

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

In this video, we delve into the holistic approach of chiropractors, seamlessly blending traditional techniques with modern integrative practices. Discover how chiropractors synergize their expertise with various medical disciplines, offering patients a comprehensive and personalized approach to wellness. From spinal adjustments to nutritional guidance, acupuncture, and mindfulness techniques, witness the transformative power of integrating chiropractic care into the broader spectrum of holistic healthcare.

We present, bridge, and connect various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.

It is all about.

LIVING, LOVING & MATTERING

Join us in improving your health.

Blessings,

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone:
phone: 915-850-0900

Licensed in Texas & New Mexico*

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information:
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

1 1

YouTube Video VVV5NTNGNC1RbUg3WVdEQ1NHUnF4T0VRLnV6VjNfQmlRdnlV

Beyond Adjustments: Chiropractic and Integrative Healthcare | El Paso, Tx (2024)

Dr. Alexander Jimenez 25 views February 15, 2024 3:49 pm

Discover expert insights, practical tips, and effective exercises to reclaim your mobility and bid farewell to sciatica discomfort. Whether you're a long-time sufferer or curious about preventative measures, this video is your ultimate guide to achieving a pain-free, active lifestyle. Say goodbye to sciatica and hello to a healthier you! 🚀 #ChiropracticCare #SciaticaRelief #RehabilitationTips

 Our care plans are base on Functional Medicine as a systems approach based on biology that focuses on identifying and addressing the root cause of disease. We focus on the paradigm that symptom or differential diagnosis may be one of many contributing factors to an individual's illness.   

This approach shifts from the traditional disease-centered focus of most medical practices to a more holistic person-centered approach.       

Our discussions team includes Integrative Doctors, Functional Medicine Experts, Nutritionists, Health Coaches, Chiropractors, Physical Medicine Doctors, Therapists, and Exercise Performance Specialists.       
We provide clinical insights, treatment options, and methods to achieve clinically sound, specific measured goals.*     

Functional & Integrative Health Live Events *   
✅ Stress Hormones & Health 
✅ Gut Health, Inflammation & Auto-Immunity* 
✅ Musculoskeletal Rehabilitation
✅ Fibromyalgia & Inflammation 
✅ Diabetes & Autoimmunity* 
✅ Weight Loss 
✅ Body Composition Analysis
✅ Thyroid Dysfunction* 
✅ Autoimmune Disorder*
✅ Heart Disease & Inflammation*
✅ Agility & Mobility 
✅ Injury Recovery Programs 
✅ Complex Lower Back Pain Recovery Plans 
✅ Severe Sciatica Syndromes 
✅ Other Complex Health Challenges
✅ Neutraceutical Recommendations
✅ Advanced Translational Nutrigenomics*
✅ Nutrigenomics, Proteomics, Metabalomics
✅ Care Plans (Advanced Clinical Practice) 
 
We present, bridge, and connect these various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.     

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.     

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.     

It is all about.   

LIVING, LOVING & MATTERING     

Join us in improving your health.     

Blessings,     

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone: 
phone: 915-850-0900   

Licensed in Texas & New Mexico*         

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.     

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.     

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.     
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*     

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: 
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com 

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

Discover expert insights, practical tips, and effective exercises to reclaim your mobility and bid farewell to sciatica discomfort. Whether you're a long-time sufferer or curious about preventative measures, this video is your ultimate guide to achieving a pain-free, active lifestyle. Say goodbye to sciatica and hello to a healthier you! ? #ChiropracticCare #SciaticaRelief #RehabilitationTips

Our care plans are base on Functional Medicine as a systems approach based on biology that focuses on identifying and addressing the root cause of disease. We focus on the paradigm that symptom or differential diagnosis may be one of many contributing factors to an individual's illness.

This approach shifts from the traditional disease-centered focus of most medical practices to a more holistic person-centered approach.

Our discussions team includes Integrative Doctors, Functional Medicine Experts, Nutritionists, Health Coaches, Chiropractors, Physical Medicine Doctors, Therapists, and Exercise Performance Specialists.
We provide clinical insights, treatment options, and methods to achieve clinically sound, specific measured goals.*

Functional & Integrative Health Live Events *
? Stress Hormones & Health
? Gut Health, Inflammation & Auto-Immunity*
? Musculoskeletal Rehabilitation
? Fibromyalgia & Inflammation
? Diabetes & Autoimmunity*
? Weight Loss
? Body Composition Analysis
? Thyroid Dysfunction*
? Autoimmune Disorder*
? Heart Disease & Inflammation*
? Agility & Mobility
? Injury Recovery Programs
? Complex Lower Back Pain Recovery Plans
? Severe Sciatica Syndromes
? Other Complex Health Challenges
? Neutraceutical Recommendations
? Advanced Translational Nutrigenomics*
? Nutrigenomics, Proteomics, Metabalomics
? Care Plans (Advanced Clinical Practice)

We present, bridge, and connect these various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.

It is all about.

LIVING, LOVING & MATTERING

Join us in improving your health.

Blessings,

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone:
phone: 915-850-0900

Licensed in Texas & New Mexico*

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information:
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

1 0

YouTube Video VVV5NTNGNC1RbUg3WVdEQ1NHUnF4T0VRLjJHS0xUTnVCZklB

Reclaim Your Mobility: Chiropractic Care for Sciatica Recovery | El Paso, Tx (2024)

Dr. Alexander Jimenez 41 views January 27, 2024 2:49 pm

Discover the powerful impact of chiropractic solutions in promoting healing and restoring well-being. Join us in exploring the path to recovery and reclaiming your health post-trauma. Your wellness journey starts here!

 Our care plans are base on Functional Medicine as a systems approach based on biology that focuses on identifying and addressing the root cause of disease. We focus on the paradigm that symptom or differential diagnosis may be one of many contributing factors to an individual's illness.   

This approach shifts from the traditional disease-centered focus of most medical practices to a more holistic person-centered approach.       

Our discussions team includes Integrative Doctors, Functional Medicine Experts, Nutritionists, Health Coaches, Chiropractors, Physical Medicine Doctors, Therapists, and Exercise Performance Specialists.       
We provide clinical insights, treatment options, and methods to achieve clinically sound, specific measured goals.*     

Functional & Integrative Health Live Events *   
✅ Stress Hormones & Health 
✅ Gut Health, Inflammation & Auto-Immunity* 
✅ Musculoskeletal Rehabilitation
✅ Fibromyalgia & Inflammation 
✅ Diabetes & Autoimmunity* 
✅ Weight Loss 
✅ Body Composition Analysis
✅ Thyroid Dysfunction* 
✅ Autoimmune Disorder*
✅ Heart Disease & Inflammation*
✅ Agility & Mobility 
✅ Injury Recovery Programs 
✅ Complex Lower Back Pain Recovery Plans 
✅ Severe Sciatica Syndromes 
✅ Other Complex Health Challenges
✅ Neutraceutical Recommendations
✅ Advanced Translational Nutrigenomics*
✅ Nutrigenomics, Proteomics, Metabalomics
✅ Care Plans (Advanced Clinical Practice) 
 
We present, bridge, and connect these various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.     

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.     

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.     

It is all about.   

LIVING, LOVING & MATTERING     

Join us in improving your health.     

Blessings,     

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone: 
phone: 915-850-0900   

Licensed in Texas & New Mexico*         

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.     

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.     

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.     
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*     

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: 
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com 

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

Discover the powerful impact of chiropractic solutions in promoting healing and restoring well-being. Join us in exploring the path to recovery and reclaiming your health post-trauma. Your wellness journey starts here!

Our care plans are base on Functional Medicine as a systems approach based on biology that focuses on identifying and addressing the root cause of disease. We focus on the paradigm that symptom or differential diagnosis may be one of many contributing factors to an individual's illness.

This approach shifts from the traditional disease-centered focus of most medical practices to a more holistic person-centered approach.

Our discussions team includes Integrative Doctors, Functional Medicine Experts, Nutritionists, Health Coaches, Chiropractors, Physical Medicine Doctors, Therapists, and Exercise Performance Specialists.
We provide clinical insights, treatment options, and methods to achieve clinically sound, specific measured goals.*

Functional & Integrative Health Live Events *
? Stress Hormones & Health
? Gut Health, Inflammation & Auto-Immunity*
? Musculoskeletal Rehabilitation
? Fibromyalgia & Inflammation
? Diabetes & Autoimmunity*
? Weight Loss
? Body Composition Analysis
? Thyroid Dysfunction*
? Autoimmune Disorder*
? Heart Disease & Inflammation*
? Agility & Mobility
? Injury Recovery Programs
? Complex Lower Back Pain Recovery Plans
? Severe Sciatica Syndromes
? Other Complex Health Challenges
? Neutraceutical Recommendations
? Advanced Translational Nutrigenomics*
? Nutrigenomics, Proteomics, Metabalomics
? Care Plans (Advanced Clinical Practice)

We present, bridge, and connect these various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.

It is all about.

LIVING, LOVING & MATTERING

Join us in improving your health.

Blessings,

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone:
phone: 915-850-0900

Licensed in Texas & New Mexico*

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information:
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

1 0

YouTube Video VVV5NTNGNC1RbUg3WVdEQ1NHUnF4T0VRLlk5TXh5LXZRNFdz

Chiropractic Care for Healing After Trauma | El Paso, Tx (2024)

Dr. Alexander Jimenez 29 views January 16, 2024 1:55 pm

Discover the transformative journey of injury recovery through chiropractic care. Explore how these healing hands and techniques aid rehabilitation, restoring wellness and vitality. Join us in uncovering the remarkable impact of chiropractic care on the path to recovery and renewed strength.

 Our care plans are base on Functional Medicine as a systems approach based on biology that focuses on identifying and addressing the root cause of disease. We focus on the paradigm that symptom or differential diagnosis may be one of many contributing factors to an individual's illness.   

This approach shifts from the traditional disease-centered focus of most medical practices to a more holistic person-centered approach.       

Our discussions team includes Integrative Doctors, Functional Medicine Experts, Nutritionists, Health Coaches, Chiropractors, Physical Medicine Doctors, Therapists, and Exercise Performance Specialists.       
We provide clinical insights, treatment options, and methods to achieve clinically sound, specific measured goals.*     

Functional & Integrative Health Live Events *   
✅ Stress Hormones & Health 
✅ Gut Health, Inflammation & Auto-Immunity* 
✅ Musculoskeletal Rehabilitation
✅ Fibromyalgia & Inflammation 
✅ Diabetes & Autoimmunity* 
✅ Weight Loss 
✅ Body Composition Analysis
✅ Thyroid Dysfunction* 
✅ Autoimmune Disorder*
✅ Heart Disease & Inflammation*
✅ Agility & Mobility 
✅ Injury Recovery Programs 
✅ Complex Lower Back Pain Recovery Plans 
✅ Severe Sciatica Syndromes 
✅ Other Complex Health Challenges
✅ Neutraceutical Recommendations
✅ Advanced Translational Nutrigenomics*
✅ Nutrigenomics, Proteomics, Metabalomics
✅ Care Plans (Advanced Clinical Practice) 
 
We present, bridge, and connect these various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.     

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.     

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.     

It is all about.   

LIVING, LOVING & MATTERING     

Join us in improving your health.     

Blessings,     

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone: 
phone: 915-850-0900   

Licensed in Texas & New Mexico*         

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.     

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.     

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.     
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*     

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: 
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com 

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

Discover the transformative journey of injury recovery through chiropractic care. Explore how these healing hands and techniques aid rehabilitation, restoring wellness and vitality. Join us in uncovering the remarkable impact of chiropractic care on the path to recovery and renewed strength.

Our care plans are base on Functional Medicine as a systems approach based on biology that focuses on identifying and addressing the root cause of disease. We focus on the paradigm that symptom or differential diagnosis may be one of many contributing factors to an individual's illness.

This approach shifts from the traditional disease-centered focus of most medical practices to a more holistic person-centered approach.

Our discussions team includes Integrative Doctors, Functional Medicine Experts, Nutritionists, Health Coaches, Chiropractors, Physical Medicine Doctors, Therapists, and Exercise Performance Specialists.
We provide clinical insights, treatment options, and methods to achieve clinically sound, specific measured goals.*

Functional & Integrative Health Live Events *
? Stress Hormones & Health
? Gut Health, Inflammation & Auto-Immunity*
? Musculoskeletal Rehabilitation
? Fibromyalgia & Inflammation
? Diabetes & Autoimmunity*
? Weight Loss
? Body Composition Analysis
? Thyroid Dysfunction*
? Autoimmune Disorder*
? Heart Disease & Inflammation*
? Agility & Mobility
? Injury Recovery Programs
? Complex Lower Back Pain Recovery Plans
? Severe Sciatica Syndromes
? Other Complex Health Challenges
? Neutraceutical Recommendations
? Advanced Translational Nutrigenomics*
? Nutrigenomics, Proteomics, Metabalomics
? Care Plans (Advanced Clinical Practice)

We present, bridge, and connect these various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.

It is all about.

LIVING, LOVING & MATTERING

Join us in improving your health.

Blessings,

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone:
phone: 915-850-0900

Licensed in Texas & New Mexico*

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information:
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

0 0

YouTube Video VVV5NTNGNC1RbUg3WVdEQ1NHUnF4T0VRLlktQjBPdmh0OXFV

The Power of Chiropractic Care in Injury Rehabilitation | El Paso, Tx (2024)

Dr. Alexander Jimenez 49 views January 8, 2024 5:33 pm

. Discover how genetics, lifestyle changes, and holistic approaches intersect to redefine wellness. From headaches to genetic predispositions, delve into the interconnected world of health and Functional Medicine’s transformative impact. Uncover the keys to holistic well-being with cutting-edge insights and expert perspectives.

 Our care plans are base on Functional Medicine as a systems approach based on biology that focuses on identifying and addressing the root cause of disease. We focus on the paradigm that symptom or differential diagnosis may be one of many contributing factors to an individual's illness.   

This approach shifts from the traditional disease-centered focus of most medical practices to a more holistic person-centered approach.       

Our discussions team includes Integrative Doctors, Functional Medicine Experts, Nutritionists, Health Coaches, Chiropractors, Physical Medicine Doctors, Therapists, and Exercise Performance Specialists.       
We provide clinical insights, treatment options, and methods to achieve clinically sound, specific measured goals.*     

Functional & Integrative Health Live Events *   
✅ Stress Hormones & Health 
✅ Gut Health, Inflammation & Auto-Immunity* 
✅ Musculoskeletal Rehabilitation
✅ Fibromyalgia & Inflammation 
✅ Diabetes & Autoimmunity* 
✅ Weight Loss 
✅ Body Composition Analysis
✅ Thyroid Dysfunction* 
✅ Autoimmune Disorder*
✅ Heart Disease & Inflammation*
✅ Agility & Mobility 
✅ Injury Recovery Programs 
✅ Complex Lower Back Pain Recovery Plans 
✅ Severe Sciatica Syndromes 
✅ Other Complex Health Challenges
✅ Neutraceutical Recommendations
✅ Advanced Translational Nutrigenomics*
✅ Nutrigenomics, Proteomics, Metabalomics
✅ Care Plans (Advanced Clinical Practice) 
 
We present, bridge, and connect these various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.     

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.     

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.     

It is all about.   

LIVING, LOVING & MATTERING     

Join us in improving your health.     

Blessings,     

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone: 
phone: 915-850-0900   

Licensed in Texas & New Mexico*         

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.     

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.     

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.     
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*     

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: 
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com 

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

. Discover how genetics, lifestyle changes, and holistic approaches intersect to redefine wellness. From headaches to genetic predispositions, delve into the interconnected world of health and Functional Medicine’s transformative impact. Uncover the keys to holistic well-being with cutting-edge insights and expert perspectives.

Our care plans are base on Functional Medicine as a systems approach based on biology that focuses on identifying and addressing the root cause of disease. We focus on the paradigm that symptom or differential diagnosis may be one of many contributing factors to an individual's illness.

This approach shifts from the traditional disease-centered focus of most medical practices to a more holistic person-centered approach.

Our discussions team includes Integrative Doctors, Functional Medicine Experts, Nutritionists, Health Coaches, Chiropractors, Physical Medicine Doctors, Therapists, and Exercise Performance Specialists.
We provide clinical insights, treatment options, and methods to achieve clinically sound, specific measured goals.*

Functional & Integrative Health Live Events *
? Stress Hormones & Health
? Gut Health, Inflammation & Auto-Immunity*
? Musculoskeletal Rehabilitation
? Fibromyalgia & Inflammation
? Diabetes & Autoimmunity*
? Weight Loss
? Body Composition Analysis
? Thyroid Dysfunction*
? Autoimmune Disorder*
? Heart Disease & Inflammation*
? Agility & Mobility
? Injury Recovery Programs
? Complex Lower Back Pain Recovery Plans
? Severe Sciatica Syndromes
? Other Complex Health Challenges
? Neutraceutical Recommendations
? Advanced Translational Nutrigenomics*
? Nutrigenomics, Proteomics, Metabalomics
? Care Plans (Advanced Clinical Practice)

We present, bridge, and connect these various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.

It is all about.

LIVING, LOVING & MATTERING

Join us in improving your health.

Blessings,

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone:
phone: 915-850-0900

Licensed in Texas & New Mexico*

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information:
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

2 0

YouTube Video VVV5NTNGNC1RbUg3WVdEQ1NHUnF4T0VRLjFtd0FXT19MN3R3

Functional Medicine's Influence Beyond Joints | El Paso, Tx (2024)

Dr. Alexander Jimenez 72 views December 28, 2023 6:10 pm

Again, We Welcome You.

Our Purpose & Passions: I am a Doctor of Chiropractic specializing in progressive, cutting-edge therapies and functional rehabilitation procedures focused on clinical physiology, total health, practical strength training, and complete conditioning. We focus on restoring normal body functions after neck, back, spinal and soft tissue injuries.

We use Specialized Chiropractic Protocols, Wellness Programs, Functional & Integrative Nutrition, Agility & Mobility Fitness Training, and Rehabilitation Systems for all ages.

As an extension to effective rehabilitation, we too offer our patients, disabled veterans, athletes, and young and elder a diverse portfolio of strength equipment, high-performance exercises, and advanced agility treatment options. We have teamed up with the city’s premier doctors, therapists, and trainers to provide high-level competitive athletes the possibility to push themselves to their highest abilities within our facilities.

We’ve been blessed to use our methods with thousands of El Pasoans over the last three decades allowing us to restore our patients’ health and fitness while implementing researched non-surgical methods and functional wellness programs.

Our programs are natural and use the body’s ability to achieve specific measured goals, rather than introducing harmful chemicals, controversial hormone replacement, unwanted surgeries, or addictive drugs. We want you to live a functional life that is fulfilled with more energy, a positive attitude, better sleep, and less pain. Our goal is to ultimately empower our patients to maintain the healthiest way of living.

With a bit of work, we can achieve optimal health together, no matter the age or disability.

Join us in improving your health for you and your family.

It’s all about: LIVING, LOVING & MATTERING!

Welcome & God Bless

EL PASO LOCATIONS

East Side: Main Clinic*
11860 Vista Del Sol, Ste 128
Phone: 915-412-6677

Central: Rehabilitation Center
6440 Gateway East, Ste B
Phone: 915-850-0900

North East Rehabilitation & Fitness Center
7100 Airport Blvd, Ste. C
Phone: 915-412-6677

Dr. Alex Jimenez DC, MSACP, CIFM, ATN, IFMCP
My Digital Business Card

Clinic Location 1

Address: 11860 Vista Del Sol Dr Suite 128
El Paso, TX 79936
Phone
: (915) 412-6677
Email: Send Email
Web: www.DrAlexJimenez.com

Clinic Location 2

Address: 6440 Gateway East, Building B
El Paso, TX 79905
Phone: (915) 850-0900
Email: Send Email
Web: www.ElPasoBackClinic.com

Clinic Location 3

Address: 1700 N Zaragoza Rd # 117
El Paso, TX 79936
Phone: (915) 850-0900
Email: Send Email
Web: www.ChiropracticScientist.com

Push As Rx Crossfit & Rehab

Address: 6440 Gateway East, Building B
El Paso, TX 79905
Phone
: (915) 412-6677
EmailSend Email
Webwww.PushAsRx.com

Push 24/7

Address: 1700 E Cliff Dr
El Paso, TX 79902
Phone
: (915) 412-6677
EmailSend Email
Webwww.PushAsRx.com

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Professional Scope of Practice *

The information herein on "The Emerging Role Of Nrf2 In Mitochondrial Function" is not intended to replace a one-on-one relationship with a qualified health care professional or licensed physician and is not medical advice. We encourage you to make healthcare decisions based on your research and partnership with a qualified healthcare professional.

Blog Information & Scope Discussions

Our information scope is limited to Chiropractic, musculoskeletal, physical medicines, wellness, contributing etiological viscerosomatic disturbances within clinical presentations, associated somatovisceral reflex clinical dynamics, subluxation complexes, sensitive health issues, and/or functional medicine articles, topics, and discussions.

We provide and present clinical collaboration with specialists from various disciplines. Each specialist is governed by their professional scope of practice and their jurisdiction of licensure. We use functional health & wellness protocols to treat and support care for the injuries or disorders of the musculoskeletal system.

Our videos, posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate to and directly or indirectly support our clinical scope of practice.*

Our office has reasonably attempted to provide supportive citations and has identified the relevant research study or studies supporting our posts. We provide copies of supporting research studies available to regulatory boards and the public upon request.

We understand that we cover matters that require an additional explanation of how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez, DC, or contact us at 915-850-0900.

We are here to help you and your family.

Blessings

Dr. Alex Jimenez DC, MSACP, RN*, CCST, IFMCP*, CIFM*, ATN*

email: coach@elpasofunctionalmedicine.com

Licensed as a Doctor of Chiropractic (DC) in Texas & New Mexico*
Texas DC License # TX5807, New Mexico DC License # NM-DC2182

Licensed as a Registered Nurse (RN*) in Florida
Florida License RN License # RN9617241 (Control No. 3558029)
Compact Status: Multi-State License: Authorized to Practice in 40 States*

Presently Matriculated: ICHS: MSN* FNP (Family Nurse Practitioner Program)

Dr. Alex Jimenez DC, MSACP, RN* CIFM*, IFMCP*, ATN*, CCST
My Digital Business Card