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El Paso, TX Oxidative Stress and Antioxidant Defense

Science based Chiropractor Dr. Alexander Jimenez takes a look at oxidative stress, what it is, how it affects the body and the antioxidant defense to remedy the situation.

Esra Birben PhD,1 Umit Murat Sahiner MD,1 Cansin Sackesen MD,1 Serpil Erzurum MD,2 and Omer Kalayci, MD1

Abstract: Reactive oxygen species (ROS) are produced by living organisms as a result of normal cellular metabolism and environ- mental factors, such as air pollutants or cigarette smoke. ROS are highly reactive molecules and can damage cell structures such as carbohydrates, nucleic acids, lipids, and proteins and alter their functions. The shift in the balance between oxidants and antioxidants in favor of oxidants is termed “oxidative stress.” Regulation of reducing and oxidizing (redox) state is critical for cell viability, activation, proliferation, and organ function. Aerobic organisms have integrated antioxidant systems, which include enzymatic and non- enzymatic antioxidants that are usually effective in blocking harmful effects of ROS. However, in pathological conditions, the antioxidant systems can be overwhelmed. Oxidative stress contributes to many pathological conditions and diseases, including cancer, neurological disorders, atherosclerosis, hypertension, ischemia/perfusion, diabetes, acute respiratory distress syndrome, idiopathic pulmonary fibrosis, chronic obstructive pulmonary disease, and asthma. In this review, we summarize the cellular oxidant and antioxidant systems and discuss the cellular effects and mechanisms of the oxidative stress.

Key Words: antioxidant, oxidant, oxidative stress, reactive oxygen species, redox

(WAO Journal 2012; 5:9–19)

Reactive oxygen species (ROS) are produced by living organisms as a result of normal cellular metabolism. At low to moderate concentrations, they function in physiological cell processes, but at high concentrations, they produce adverse modifications to cell components, such as lipids, proteins, and DNA.1–6 The shift in balance between oxidant/ antioxidant in favor of oxidants is termed “oxidative stress.” Oxidative stress contributes to many pathological conditions, including cancer, neurological disorders,7–10 atherosclerosis, hypertension, ischemia/perfusion,11–14 diabetes, acute respiratory distress syndrome, idiopathic pulmonary fibrosis, chronic obstructive pulmonary disease,15 and asthma.16–21 Aerobic organisms have integrated antioxidant systems,  which include enzymatic and nonenzymatic antioxidants that are usually effective in blocking harmful effects of ROS. However, in pathological conditions, the antioxidant systems can be overwhelmed. In this review, we summarize the cellular oxidant and antioxidant systems and regulation of the reducing and oxidizing (redox) state in health and disease states.

OXIDANTS

Endogenous Sources of ROS

ROS are produced from molecular oxygen as a result of normal cellular metabolism. ROS can be divided into 2 groups: free radicals and nonradicals. Molecules containing one or more unpaired electrons and thus giving reactivity to the molecule are called free radicals. When 2 free radicals share their unpaired electrons, nonradical forms are created. The 3 major ROS that are of physiological significance are superoxide anion (O22.), hydroxyl radical ( OH), and hydro- gen peroxide (H2O2). ROS are summarized in Table 1.

Superoxide anion is formed by the addition of 1 electron to the molecular oxygen.22 This process is mediated by nicotine adenine dinucleotide phosphate [NAD(P)H] oxidase or xanthine oxidase or by mitochondrial electron trans- port system. The major site for producing superoxide anion is the mitochondria, the machinery of the cell to produce adenosine triphosphate. Normally, electrons are transferred through mitochondrial electron transport chain for reduction of oxygen to water, but approximately 1 to 3% of all electrons leak from the system and produce superoxide. NAD(P)H oxidase is found in polymorphonuclear leukocytes, monocytes, and macrophages. Upon phagocytosis, these cells produce a burst of superoxide that lead to bactericidal activity. Superoxide is converted into hydrogen peroxide by the action of superoxide dismutases (SODs, EC 1.15.1.1). Hydrogen peroxide easily diffuses across the plasma membrane. Hydrogen peroxide is also produced by xanthine oxidase, amino acid oxidase, and NAD(P)H oxidase 23,24 and in peroxisomes by consumption of molecular oxygen in metabolic reactions. In a succession of reactions called Haber–Weiss and Fenton reactions,H2O2 can breakdown to OH2 in the presence of transmission metals like Fe21 or Cu21.25

Fe31 + .O2 →Fe2 + O2 Haber Weiss

Fe2 + H2O2 →Fe3 + OH + .OH Fenton reaction

O 2  itself can also react with H2 O2 and generate OH .26,27 Hydroxyl radical is the most reactive of ROS and can damage proteins, lipids, and carbohydrates and DNA. It can also start lipid peroxidation by taking an electron from polyunsaturated fatty acids.

Granulocytic enzymes further expand the reactivity of H2O2 via eosinophil peroxidase and myeloperoxidase (MPO). In activated neutrophils, H2O2 is consumed by MPO. In the presence of chloride ion, H2O2 is converted to hypochlorous acid (HOCl). HOCl is highly oxidative and plays an important role in killing of the pathogens in the airways.28 However, HOCl can also react with DNA and induce DNA–protein interactions and produce pyrimidine oxidation products and add chloride to DNA bases.29,30 Eosinophil peroxidase and MPO also contribute to the oxidative stress by modification of proteins by halogenations, nitration, and protein cross-links via tyrosyl radicals.31–33

Other oxygen-derived free radicals are the peroxyl radicals (ROO$ ). Simplest form of these radicals is hydro- peroxyl radical (HOO$ ) and has a role in fatty acid peroxidation. Free radicals can trigger lipid peroxidation chain reactions by abstracting a hydrogen atom from a side- chain methylene carbon. The lipid radical then reacts with oxygen to produce peroxyl radical. Peroxyl radical initiates a chain reaction and transforms polyunsaturated fatty acids into lipid hydroperoxides. Lipid hydroperoxides are very unstable and easily decompose to secondary products, such as aldehydes (such as 4-hydroxy-2,3-nonenal) and malondialdehydes (MDAs). Isoprostanes are another group of lipid peroxidation products that are generated via the peroxidation of arachidonic acid and have also been found to be elevated in plasma and breath condensates of asthmatics.34,35 Peroxidation of lipids disturbs the integrity of cell membranes and leads to rearrangement of membrane structure.

Hydrogen peroxide, superoxide radical, oxidized glutathione (GSSG), MDAs, isoprostanes, carbonyls, and nitrotyrosine can be easily measured from plasma, blood, or bronchoalveolar lavage samples as biomarkers of oxidation by standardized assays.

Exogenous Source of Oxidants

Cigarette Smoke

Cigarette smoke contains many oxidants and free radicals and organic compounds, such as superoxide and nitric oxide.36 In addition, inhalation of cigarette smoke into the lung also activates some endogenous mechanisms, such as accumulation of neutrophils and macrophages, which further increase the oxidant injury.

Ozone Exposure

Ozone exposure can cause lipid peroxidation and induce influx of neutrophils into the airway epithelium. Short-term exposure to ozone also causes the release of inflammatory mediators, such as MPO, eosinophil cationic proteins and also lactate dehydrogenase and albumin.37 Even in healthy subjects, ozone exposure causes a reduction in pulmonary functions.38 Cho et al39 have shown that particulate matter (mixture of solid particles and liquid droplets suspended in the air) catalyzes the reduction of oxygen.

Hyperoxia

Hyperoxia refers to conditions of higher oxygen levels than normal partial pressure of oxygen in the lungs or other body tissues. It leads to greater production of reactive oxygen and nitrogen species.40,41

Ionizing Radiation

Ionizing radiation, in the presence of O2, converts hydroxyl radical, superoxide, and organic radicals to hydrogen peroxide and organic hydroperoxides. These hydroperoxide species react with redox active metal ions, such as Fe and Cu, via Fenton reactions and thus induce oxidative stress.42,43 Narayanan et al44 showed that fibroblasts that were exposed to alpha particles had significant increases in intracellular O2 2. and H2O2 production via plasma membrane-bound NADPH oxidase.44 Signal transduction molecules, such as extracellular signal-regulated kinase 1 and 2 (ERK1/2), c-Jun N-terminal kinase (JNK), and p38, and transcription factors, such as activator protein-1 (AP-1), nuclear factor-kB (NF-kB), and p53, are activated, which result in the expression of radiation response–related genes.45–50 Ultraviolet A (UVA) photons trigger oxidative reactions by excitation of endogenous photosensitizers, such as porphyrins, NADPH oxidase, and riboflavins. 8-Oxo-7,8- dihydroguanine (8-oxoGua) is the main UVA-mediated DNA oxidation product formed by the oxidation of OH radical, 1-electron oxidants, and singlet oxygen that mainly reacts with guanine.51 The formation of guanine radical cation in isolated DNA has been shown to efficiently occur through the direct effect of ionizing radiation.52,53 After exposure to ionizing radiation, intracellular level of glutathione (GSH) decreases for a short term but then increases again.54

Heavy Metal Ions

Heavy metal ions, such as iron, copper, cadmium, mercury, nickel, lead, and arsenic, can induce generation of reactive radicals and cause cellular damage via depletion of enzyme activities through lipid peroxidation and reaction with nuclear proteins and DNA.55

One of the most important mechanisms of metal- mediated free radical generation is via a Fenton-type reaction. Superoxide ion and hydrogen peroxide can interact with transition metals, such as iron and copper, via the metal catalyzed Haber–Weiss/Fenton reaction to form OH radicals.

Metal31 1 $O2 /Metal21 1 O2 Haber Weiss Metal21 1 H2 O2 /Metal31 1 OH 2 1 $OH Fenton reaction

Besides the Fenton-type and Haber–Weiss-type mechanisms, certain metal ions can react directly with cellular molecules to generate free radicals, such as thiol radicals, or induce cell signaling pathways. These radicals may also react with other thiol molecules to generate O22.. O22. is converted to H2O2, which causes additional oxygen radical generation. Some metals, such as arsenite, induce ROS formation indirectly by activation of radical producing systems in cells.56

Arsenic is a highly toxic element that produces a variety of ROS, including superoxide (O2 2), singlet oxygen (1O2), peroxyl radical (ROO ), nitric oxide (NO ), hydrogen peroxide (H2O2), and dimethylarsinic peroxyl radicals [(CH3)2AsOO ].57–59 Arsenic (III) compounds can inhibit antioxidant enzymes, especially the GSH-dependent enzymes, such as glutathione-S-transferases (GSTs), glutathione peroxidase (GSH-Px), and GSH reductase, via bind- ing to their sulfhydryl (–SH) groups.60,61

Lead increases lipid peroxidation.62 Significant decreases in the activity of tissue SOD and brain GPx have been reported after lead exposure.63,64 Replacement of zinc, which serves as a cofactor for many enzymes by lead, leads to inactivation of such enzymes. Lead exposure may cause inhibition of GST by affecting tissue thiols.

ROS generated by metal-catalyzed reactions can mod- ify DNA bases. Three base substitutions, G / C, G / T, and C / T, can occur as a result of oxidative damage by metal ions, such as Fe21, Cu21, and Ni21. Reid et al65 showed that G / C was predominantly produced by Fe21 while C / T substitution was by Cu21 and Ni21.

ANTIOXIDANTS

The human body is equipped with a variety of antioxidants that serve to counterbalance the effect of oxidants. For all practical purposes, these can be divided into 2 categories: enzymatic (Table 2) and nonenzymatic (Table 3).

Enzymatic Antioxidants

The major enzymatic antioxidants of the lungs are SODs (EC 1.15.1.11), catalase (EC 1.11.1.6), and GSH-Px (EC 1.11.1.9). In addition to these major enzymes, other antioxidants, including heme oxygenase-1 (EC 1.14.99.3), and redox proteins, such as thioredoxins (TRXs, EC 1.8.4.10), peroxiredoxins (PRXs, EC 1.11.1.15), and glutaredoxins, have also been found to play crucial roles in the pulmonary antioxidant defenses.

Since superoxide is the primary ROS produced from a variety of sources, its dismutation by SOD is of primary importance for each cell. All 3 forms of SOD, that is, CuZn- SOD, Mn-SOD, and EC-SOD, are widely expressed in the human lung. Mn-SOD is localized in the mitochondria matrix. EC-SOD is primarily localized in the extracellular matrix, especially in areas containing high amounts of type I collagen fibers and around pulmonary and systemic vessels. It has also been detected in the bronchial epithelium, alveolar epithelium, and alveolar macrophages.66,67 Overall, CuZn- SOD and Mn-SOD are generally thought to act as bulk scavengers of superoxide radicals. The relatively high EC-SOD level in the lung with its specific binding to the extracellular matrix components may represent a fundamental component of lung matrix protection.68

H2O2 that is produced by the action of SODs or the action of oxidases, such as xanthine oxidase, is reduced to water by catalase and the GSH-Px. Catalase exists as a tetra- mer composed of 4 identical monomers, each of which con- tains a heme group at the active site. Degradation of H2O2 is accomplished via the conversion between 2 conformations of catalase-ferricatalase (iron coordinated to water) and com- pound I (iron complexed with an oxygen atom). Catalase also binds NADPH as a reducing equivalent to prevent oxidative inactivation of the enzyme (formation of compound II) by H2O2 as it is reduced to water.69

Enzymes in the redox cycle responsible for the reduction of H2O2 and lipid hydroperoxides (generated as a result of membrane lipid peroxidation) include the GSH-Pxs.70 The GSH-Pxs are a family of tetrameric enzymes that contain the unique amino acid selenocysteine within the active sites and use low-molecular-weight thiols, such as GSH, to reduce H2O2 and lipid peroxides to their corresponding alcohols. Four GSH- Pxs have been described, encoded by different genes: GSH- Px-1 (cellular GSH-Px) is ubiquitous and reduces H2O2 and fatty acid peroxides, but not esterified peroxyl lipids.71 Esterified lipids are reduced by membrane-bound GSH-Px-4 (phospholipid hydroperoxide GSH-Px), which can use several different low-molecular-weight thiols as reducing equivalents. GSH-Px-2 (gastrointestinal GSH-Px) is localized in gastrointestinal epithelial cells where it serves to reduce dietary peroxides.72 GSH-Px-3 (extracellular GSH-Px) is the only member of the GSH-Px family that resides in the extracellular compartment and is believed to be one of the most important extracellular antioxidant enzyme in mammals. Of these, extracellular GSH-Px is most widely investigated in the human lung.73

In addition, disposal of H2O2 is closely associated with several thiol-containing enzymes, namely, TRXs (TRX1 and TRX2), thioredoxin reductases (EC 1.8.1.9) (TRRs), PRXs (which are thioredoxin peroxidases), and glutaredoxins.74

Two TRXs and TRRs have been characterized in human cells, existing in both cytosol and mitochondria. In the lung, TRX and TRR are expressed in bronchial and alveolar epithelium and macrophages. Six different PRXs have been found in human cells, differing in their ultrastructural compartmentalization. Experimental studies have revealed the importance of PRX VI in the protection of alveolar epithelium. Human lung expresses all PRXs in bronchial epithelium, alveolar epithelium, and macrophages.75 PRX V has recently been found to function as a peroxynitrite reductase,76 which means that it may function as a potential protective compound in the development of ROS-mediated lung injury.77

Common to these antioxidants is the requirement of NADPH as a reducing equivalent. NADPH maintains catalase in the active form and is used as a cofactor by TRX and GSH reductase (EC 1.6.4.2), which converts GSSG to GSH, a co-substrate for the GSH-Pxs. Intracellular NADPH, in turn, is generated by the reduction of NADP1 by glucose-6-phosphate dehydrogenase, the first and rate-limiting enzyme of the pen- tose phosphate pathway, during the conversion of glucose- 6-phosphate to 6-phosphogluconolactone. By generating NADPH, glucose-6-phosphate dehydrogenase is a critical determinant of cytosolic GSH buffering capacity (GSH/ GSSG) and, therefore, can be considered an essential, regulatory antioxidant enzyme.78,79

GSTs (EC 2.5.1.18), another antioxidant enzyme family, inactivate secondary metabolites, such as unsaturated aldehydes, epoxides, and hydroperoxides. Three major families of GSTs have been described: cytosolic GST, mitochondrial GST,80,81 and membrane-associated microsomal GST that has a role in eicosanoid and GSH metabolism.82 Seven classes of cytosolic GST are identified in mammalian, designated Alpha, Mu, Pi, Sigma, Theta, Omega, and Zeta.83–86 During non-stressed conditions, class Mu and Pi GSTs interact with kinases Ask1 and JNK, respectively, and inhibit these kinases.87–89 It has been shown that GSTP1 dissociates from JNK in response to oxidative stress.89 GSTP1 also physically interacts with PRX VI and leads to recovery of PRX enzyme activity via glutathionylation of the oxidized protein.90

Nonenzymatic Antioxidants

Nonenzymatic antioxidants include low-molecular-weight compounds, such as vitamins (vitamins C and E), b-carotene, uric acid, and GSH, a tripeptide (L-g-glutamyl-L-cysteinyl-L- glycine) that comprise a thiol (sulfhydryl) group.

Vitamin C (Ascorbic Acid)

Water-soluble vitamin C (ascorbic acid) provides intracellular and extracellular aqueous-phase antioxidant capacity primarily by scavenging oxygen free radicals. It converts vitamin E free radicals back to vitamin E. Its plasma levels have been shown to decrease with age.91,92

Vitamin E (a-Tocopherol)

Lipid-soluble vitamin E is concentrated in the hydrophobic interior site of cell membrane and is the principal defense against oxidant-induced membrane injury. Vitamin E donates electron to peroxyl radical, which is produced during lipid peroxidation. a-Tocopherol is the most active form of vitamin E and the major membrane-bound antioxidant in cell. Vitamin E triggers apoptosis of cancer cells and inhibits free radical formations.93

Glutathione

GSH is highly abundant in all cell compartments and is the major soluble antioxidant. GSH/GSSG ratio is a major determinant of oxidative stress. GSH shows its antioxidant effects in several ways.94 It detoxifies hydrogen peroxide and lipid peroxides via action of GSH-Px. GSH donates its electron to H2O2 to reduce it into H2O and O2. GSSG is again reduced into GSH by GSH reductase that uses NAD(P)H as the electron donor. GSH-Pxs are also important for the pro- tection of cell membrane from lipid peroxidation. Reduced glutathione donates protons to membrane lipids and protects them from oxidant attacks.95

GSH is a cofactor for several detoxifying enzymes, such as GSH-Px and transferase. It has a role in converting vitamin C and E back to their active forms. GSH protects cells against apoptosis by interacting with proapoptotic and antiapoptotic signaling pathways.94 It also regulates and activates several transcription factors, such as AP-1, NF-kB, and Sp-1.

Carotenoids (b-Carotene)

Carotenoids are pigments found in plants. Primarily, b-carotene has been found to react with peroxyl (ROO ), hydroxyl ( OH), and superoxide (O22.) radicals.96 Carotenoids show their antioxidant effects in low oxygen partial pressure but may have pro-oxidant effects at higher oxygen concentrations.97 Both carotenoids and retinoic acids (RAs) are capable of regulating transcription factors.98 b-Carotene inhibits the oxidant-induced NF-kB activation and interleukin (IL)-6 and tumor necrosis factor-a production. Carotenoids also affect apoptosis of cells. Antiproliferative effects of RA have been shown in several studies. This effect of RA is mediated mainly by retinoic acid receptors and vary among cell types. In mammary carcinoma cells, retinoic acid receptor was shown to trigger growth inhibition by inducing cell cycle arrest, apoptosis, or both.99,100

THE EFFECT OF OXIDATIVE STRESS: GENETIC, PHYSIOLOGICAL, & BIOCHEMICAL MECHANISMS

Oxidative stress occurs when the balance between antioxidants and ROS are disrupted because of either depletion of antioxidants or accumulation of ROS. When oxidative stress occurs, cells attempt to counteract the oxidant effects and restore the redox balance by activation or silencing of genes encoding defensive enzymes, tran- scription factors, and structural proteins.101,102 Ratio between oxidized and reduced glutathione (2GSH/GSSG) is one of the important determinants of oxidative stress in the body. Higher production of ROS in body may change DNA structure, result in modification of proteins and lipids, activation of several stress-induced transcription factors, and production of pro-inflammatory and anti-inflammatory cytokines.

Effects Of Oxidative Stress On DNA

ROS can lead to DNA modifications in several ways, which involves degradation of bases, single- or double- stranded DNA breaks, purine, pyrimidine or sugar-bound modifications, mutations, deletions or translocations, and cross-linking with proteins. Most of these DNA modifications (Fig. 1) are highly relevant to carcinogenesis, aging, and neurodegenerative, cardiovascular, and autoimmune diseases. Tobacco smoke, redox metals, and nonredox metals, such as iron, cadmium, chrome, and arsenic, are also involved in carcinogenesis and aging by generating free radicals or bind- ing with thiol groups. Formation of 8-OH-G is the best- known DNA damage occurring via oxidative stress and is a potential biomarker for carcinogenesis.

Promoter regions of genes contain consensus sequences for transcription factors. These transcription factor–binding sites contain GC-rich sequences that are susceptible for oxidant attacks. Formation of 8-OH-G DNA in transcription factor binding sites can modify binding of transcription factors and thus change the expression of related genes as has been shown for AP-1 and Sp-1 target sequences.103 Besides 8-OH-G, 8,59 -cyclo-29 -deoxyadenosine (cyclo-dA) has also been shown to inhibit transcription from a reporter gene in a cell system if located in a TATA box.104 The TATA-binding protein initiates transcription by changing the bending of DNA. The binding of TATA-binding protein may be impaired by the presence of cyclo-dA.

Oxidative stress causes instability of microsatellite (short tandem repeats) regions. Redox active metal ions, hydroxyl radicals increase microsatellite instability.105 Even though single-stranded DNA breaks caused by oxidant injury can easily be tolerated by cells, double-stranded DNA breaks induced by ionizing radiation can be a significant threat for the cell survival.106

Methylation at CpG islands in DNA is an important epigenetic mechanism that may result in gene silencing. Oxidation of 5-MeCyt to 5-hydroxymethyl uracil (5-OHMeUra) can occur via deamination/oxidation reactions of thymine or 5-hydroxymethyl cytosine intermediates.107 In addition to the modulating gene expression, DNA methylation also seems to affect chromatin organization.108 Aberrant DNA methylation patterns induced by oxidative attacks also affect DNA repair activity.

Effects Of Oxidative Stress On Lipids

ROS can induce lipid peroxidation and disrupt the membrane lipid bilayer arrangement that may inactivate membrane-bound receptors and enzymes and increase tissue permeability.109 Products of lipid peroxidation, such as MDA and unsaturated aldehydes, are capable of inactivating many cellular proteins by forming protein cross-linkages.110–112 4-Hydroxy-2-nonenal causes depletion of intracellular GSH and induces of peroxide production,113,114 activates epidermal growth factor receptor,115 and induces fibronectin production.116 Lipid peroxidation products, such as isoprostanes and thiobarbituric acid reactive substances, have been used as indirect biomarkers of oxidative stress, and increased levels were shown in the exhaled breath condensate or bronchoalveolar lavage fluid or lung of chronic obstructive pulmonary disease patients or smokers.117–119

Effects Of Oxidative Stress on Proteins

ROS can cause fragmentation of the peptide chain, alteration of electrical charge of proteins, cross-linking of proteins, and oxidation of specific amino acids and therefore lead to increased susceptibility to proteolysis by degradation by specific proteases.120 Cysteine and methionine residues in proteins are particularly more susceptible to oxidation.121 Oxidation of sulfhydryl groups or methionine residues of proteins cause conformational changes, protein unfolding, and degradation.8,121–123 Enzymes that have metals on or close to their active sites are especially more sensitive to metal catalyzed oxidation. Oxidative modification of enzymes has been shown to inhibit their activities.124,125

In some cases, specific oxidation of proteins may take place. For example, methionine can be oxidized methionine sulfoxide126 and phenylalanine to o-tyrosine127; sulfhydryl groups can be oxidized to form disulfide bonds;128 and carbonyl groups may be introduced into the side chains of proteins. Gamma rays, metal-catalyzed oxidation, HOCl, and ozone can cause formation of carbonyl groups.129

Effects of Oxidative Stress on Signal Transduction

ROS can induce expression of several genes involved in signal transduction.1,130 A high ratio for GSH/GSSG is important for the protection of the cell from oxidative dam- age. Disruption of this ratio causes activation of redox sensitive transcription factors, such as NF-kB, AP-1, nuclear factor of activated T cells and hypoxia-inducible factor 1 , that are involved in the inflammatory response. Activation of transcription factors via ROS is achieved by signal transduction cascades that transmit the information from outside to the inside of cell. Tyrosine kinase receptors, most of the growth factor receptors, such as epidermal growth factor receptor, vascular endothelial growth factor receptor, and receptor for platelet-derived growth factor, protein tyrosine phosphatases, and serine/threonine kinases are targets of ROS.131–133 Extra- cellular signal-regulated kinases, JNK, and p38, which are the members of mitogen-activated protein kinase family and involved in several processes in cell including proliferation, differentiation, and apoptosis, also can be regulated by oxidants.

Under oxidative stress conditions, cysteine residues in the DNA-binding site of c-Jun, some AP-1 subunits, and inhibitory k-B kinase undergo reversible S-glutathiolation. Glutaredoxin and TRX have been reported to play an important role in regulation of redox-sensitive signaling pathways, such as NF-kB and AP-1, p38 mitogen-activated protein kinase, and JNK.134–137

NF-kB can be activated in response to oxidative stress conditions, such as ROS, free radicals, and UV irradiation.138 Phosphorylation of IkB frees NF-kB and allows it to enter the nucleus to activate gene transcription.139 A number of kinases have been reported to phosphorylate IkBs at the serine residues. These kinases are the targets of oxidative signals for activation of NF-kB.140 Reducing agents enhance NF-kB DNA binding, whereas oxidizing agents inhibit DNA binding of NF-kB. TRX may exert 2 opposite actions in regulation of NF-kB: in the cytoplasm, it blocks degradation of IkB and inhibits NF-kB activation but enhances NF-kB DNA binding in the nucleus.141 Activation of NF-kB via oxidation-related degradation of IkB results in the activation of several antioxidant defense–related genes. NF-kB regulates the expression of several genes that participate in immune response, such as IL-1b, IL-6, tumor necrosis factor-a, IL-8, and several adhesion molecules.142,143 NF-kB also regulates angiogenesis and proliferation and differentiation of cells.

AP-1 is also regulated by redox state. In the presence of H2O2, some metal ions can induce activation of AP-1. Increase in the ratio of GSH/GSSG enhances AP-1 binding while GSSG inhibits the DNA binding of AP-1.144 DNA binding of the Fos/Jun heterodimer is increased by the reduction of a single conserved cysteine in the DNA-binding domain of each of the proteins,145 while DNA binding of AP-1 can be inhibited by GSSG in many cell types, suggesting that disulphide bond formation by cysteine residues inhibits AP-1 DNA binding.146,147 Signal transduction via oxidative stress is summarized in Figure 2.

CONCLUSIONS

Oxidative stress can arise from overproduction of ROS by metabolic reactions that use oxygen and shift the balance between oxidant/antioxidant statuses in favor of the oxidants. ROS are produced by cellular metabolic activities and environmental factors, such as air pollutants or cigarette smoke. ROS are highly reactive molecules because of unpaired electrons in their structure and react with several biological macromolecules in cell, such as carbohydrates, nucleic acids, lipids, and proteins, and alter their functions. ROS also affects the expression of several genes by upregulation of redox-sensitive transcription factors and chromatin remodeling via alteration in histone acetylation/ deacetylation. Regulation of redox state is critical for cell viability, activation, proliferation, and organ function.

References:

REFERENCES

  1. Valko M, Rhodes CJ, Moncol J, Izakovic M, Mazur M. Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem Biol Interact. 2006;160:1–40.
  2. Halliwell B, Gutteridge JMC. Free Radicals in Biology and Medicine. 3rd ed. New York: Oxford University Press;1999.
  3. Marnett LJ. Lipid peroxidationdDNA damage by malondialdehyde. Mutat Res. 1999;424:83–95.
  4. Siems WG, Grune T, Esterbauer H. 4-Hydroxynonenal formation during ischemia and reperfusion of rat small intestine.  Life Sci. 1995;57:785–789.
  5. Stadtman ER. Role of oxidant species in aging. Curr Med Chem. 2004;11:1105–1112.
  6. Wang MY, Dhingra K, Hittelman WN, Liehr JG, deAndrade M, Li DH. Lipid peroxidation-induced putative malondialdehyde–DNA adducts in human breast tissues. Cancer Epidemiol Biomarkers Prev. 1996;5:705–710.
  7. Jenner P. Oxidative stress in Parkinson’s disease. Ann Neurol. 2003;53: S26–S36.
  8. Lyras L, Cairns NJ, Jenner A, Jenner P, Halliwell B. An assessment of oxidative damage to proteins, lipids, and DNA in brain from patients with Alzheimer’s disease. J Neurochem. 1997;68:2061–2069.
  9. Sayre LM, Smith MA, Perry G. Chemistry and biochemistry of oxidative stress in neurodegenerative disease. Curr Med Chem. 2001;8:721–738.
  10. Toshniwal PK, Zarling EJ. Evidence for increased lipid peroxidation in multiple sclerosis. Neurochem Res. 1992;17:205–207.
  11. Dhalla NS, Temsah RM, Netticadan T. Role of oxidative stress in cardiovascular diseases. J Hypertens. 2000;18:655–673.
  12. Kasparova S, Brezova V, Valko M, Horecky J, Mlynarik V, et al. Study of the oxidative stress in a rat model of chronic brain hypoperfusion. Neurochem Int. 2005;46:601–611.
  13. Kerr S, Brosnan MJ, McIntyre M, Reid JL, Dominiczak AF, Hamilton CA. Superoxide anion production is increased in a model of genetic hypertension: role of the endothelium. Hypertension. 1999;33:1353–1358.
  14. Kukreja RC, Hess ML. The oxygen free-radical system: from equations through membrane–protein interactions to cardiovascular injury and protection. Cardiovasc Res. 1992;26:641–655.
  15. Asami S, Manabe H, Miyake J, Tsurudome Y, Hirano T, et al. Cigarette smoking induces an increase in oxidative DNA damage, 8-hydroxydeoxyguanosine, in a central site of the human lung. Carcinogenesis. 1997;18:1763–1766.
  16. Andreadis AA, Hazen SL, Comhair SA, Erzurum SC. Oxidative and nitrosative events in asthma. Free Radic Biol Med. 2003;35:213–225.
  17. Comhair SA, Ricci KS, Arroliga M, Lara AR, Dweik RA, et al. Correlation of systemic superoxide dismutase deficiency to airflow obstruction in asthma. Am J Respir Crit Care Med. 2005;172:306–313.
  18. Comhair SA, Xu W, Ghosh S, Thunnissen FB, Almasan A, et al. Superoxide dismutase inactivation in pathophysiology of asthmatic airway remodeling and reactivity. Am J Pathol. 2005;166:663–674.
  19. Dut R, Dizdar EA, Birben E, Sackesen C, Soyer OU, Besler T, Kalayci O. Oxidative stress and its determinants in the airways of children with asthma. Allergy. 2008;63:1605–1609.

  20. Ercan H, Birben E, Dizdar EA, Keskin O, Karaaslan C, et al. Oxidative stress and genetic and epidemiologic determinants of oxidant injury in childhood asthma. J Allergy Clin Immunol. 2006;118:1097–1104.

  21. Fitzpatrick AM, Teague WG, Holguin F, Yeh M, Brown LA. Severe Asthma Research Program. Airway glutathione homeostasis is altered in children with severe asthma: evidence for oxidant stress. J Allergy Clin Immunol. 2009;123:146–152.
  22. Miller DM, Buettner GR, Aust SD. Transition metals as catalysts of “autoxidation” reactions. Free Radic Biol Med. 1990;8:95–108.
  23. Dupuy C, Virion A, Ohayon R, Kaniewski J, Dème D, Pommier J. Mechanism of hydrogen peroxide formation catalyzed by NADPH oxidase in thyroid plasma membrane. J Biol Chem. 1991;266:3739–3743.
  24. Granger DN. Role of xanthine oxidase and granulocytes in ischemiareperfusion injury. Am J Physiol. 1988;255:H1269–H1275.
  25. Fenton HJH. Oxidation of tartaric acid in the presence of iron. J Chem Soc. 1984;65:899–910.
  26. Haber F, Weiss JJ. The catalytic decomposition of hydrogen peroxide by iron salts. Proc R Soc Lond Ser A. 1934;147:332–351.
  27. Liochev SI, Fridovich I. The Haber–Weiss cycled70 years later: an alternative view. Redox Rep. 2002;7:55–57.
  28. Klebanoff SJ. Myeloperoxidase: friend and foe. J Leukoc Biol. 2005;77:598–625.
  29. Whiteman M, Jenner A, Halliwell B. Hypochlorous acid-induced base modifications in isolated calf thymus DNA. Chem Res Toxicol. 1997;10:1240–1246.
  30. Kulcharyk PA, Heinecke JW. Hypochlorous acid produced by the myeloperoxidase system of human phagocytes induces covalent cross-links between DNA and protein. Biochemistry. 2001;40:3648–3656.
  31. Brennan ML, Wu W, Fu X, Shen Z, Song W, et al. A tale of two controversies: defining both the role of peroxidases in nitrotyrosine formation in vivo using eosinophil peroxidase and myeloperoxidasedeficient mice, and the nature of peroxidase-generated reactive nitrogen species. J Biol Chem. 2002;277:17415–17427.
  32. Denzler KL, Borchers MT, Crosby JR, Cieslewicz G, Hines EM, et al. Extensive eosinophil degranulation and peroxidase-mediated oxidation of airway proteins do not occur in a mouse ovalbumin-challenge model of pulmonary inflammation. J Immunol. 2001;167:1672–1682.
  33. van Dalen CJ, Winterbourn CC, Senthilmohan R, Kettle AJ. Nitrite as a substrate and inhibitor of myeloperoxidase. Implications for nitration and hypochlorous acid production at sites of inflammation. J Biol Chem. 2000;275:11638–11644.
  34. Wood LG, Fitzgerald DA, Gibson PG, Cooper DM, Garg ML. Lipid peroxidation as determined by plasma isoprostanes is related to disease severity in mild asthma. Lipids. 2000;35:967–974.
  35. Montuschi P, Corradi M, Ciabattoni G, Nightingale J, Kharitonov SA, Barnes PJ. Increased 8-isoprostane, a marker of oxidative stress, in exhaled condensate of asthma patients. Am J Respir Crit Care Med. 1999;160:216–220.
  36. Church DF, Pryor WA. Free-radical chemistry of cigarette smoke and its toxicological implications. Environ Health Perspect. 1985;64:111–126.
  37. Hiltermann JT, Lapperre TS, van Bree L, Steerenberg PA, Brahim JJ, et al. Ozone-induced inflammation assessed in sputum and bronchial lavage fluid from asthmatics: a new noninvasive tool in epidemiologic studies on air pollution and asthma. Free Radic Biol Med. 1999;27:1448–1454.
  38. Nightingale JA, Rogers DF, Barnes PJ. Effect of inhaled ozone on exhaled nitric oxide, pulmonary function, and induced sputum in normal and asthmatic subjects. Thorax. 1999;54:1061–1069.
  39. Cho AK, Sioutas C, Miguel AH, Kumagai Y, Schmitz DA, et al. Redox activity of airborne particulate matter at different sites in the Los Angeles Basin. Environ Res. 2005;99:40–47.
  40. Comhair SA, Thomassen MJ, Erzurum SC. Differential induction of extracellular glutathione peroxidase and nitric oxide synthase 2 in airways of healthy individuals exposed to 100% O(2) or cigarette smoke. Am J Respir Cell Mol Biol. 2000;23:350–354.
  41. Matthay MA, Geiser T, Matalon S, Ischiropoulos H. Oxidant-mediated lung injury in the acute respiratory distress syndrome. Crit Care Med. 1999;27:2028–2030.
  42. Biaglow JE, Mitchell JB, Held K. The importance of peroxide and superoxide in the X-ray response. Int J Radiat Oncol Biol Phys. 1992;22:665–669.
  43. Chiu SM, Xue LY, Friedman LR, Oleinick NL. Copper ion-mediated sensitization of nuclear matrix attachment sites to ionizing radiation. Biochemistry. 1993;32:6214–6219.
  44. Narayanan PK, Goodwin EH, Lehnert BE. Alpha particles initiate biological production of superoxide anions and hydrogen peroxide in human cells. Cancer Res. 1997;57:3963–3971.
  45. Tuttle SW, Varnes ME, Mitchell JB, Biaglow JE. Sensitivity to chemical oxidants and radiation in CHO cell lines deficient in oxidative pentose cycle activity. Int J Radiat Oncol Biol Phys. 1992;22: 671–675.
  46. Guo G, Yan-Sanders Y, Lyn-Cook BD, Wang T, Tamae D, et al. Manganese
    superoxide dismutase-mediated gene expression in radiationinduced
    adaptive responses. Mol Cell Biol. 2003;23:2362–2378.
  47. Azzam EI, de Toledo SM, Spitz DR, Little JB. Oxidative metabolism
    modulates signal transduction and micronucleus formation in bystander
    cells from a-particle irradiated normal human fibroblasts. Cancer Res.
    2002;62:5436–5442.
  48. Leach JK, Van Tuyle G, Lin PS, Schmidt-Ullrich R, Mikkelsen RB.
    Ionizing radiation-induced, mitochondria-dependent generation of reactive
    oxygen/nitrogen. Cancer Res. 2001;61:3894–3901.
  49. Dent P, Yacoub A, Fisher PB, Hagan MP, Grant S. MAPK pathways in
    radiation responses. Oncogene. 2003;22:5885–5896.
  50. Wei SJ, Botero A, Hirota K, Bradbury CM, Markovina S, et al. Thioredoxin
    nuclear translocation and interaction with redox factor-1 activates the AP-1 transcription factor in response to ionizing radiation. Cancer Res. 2000;60:6688–6695.
  51. Cadet J, Douki T, Gasparutto D, Ravanat JL. Oxidative damage to DNA: formation, measurement and biochemical features. Mutat Res. 2003;531:5–23.
  52. Yokoya A, Cunniffe SM, O’Neill P. Effect of hydration on the induction of strand breaks and base lesions in plasmid DNA films by gammaradiation. J Am Chem Soc. 2002;124:8859–8866.
  53. Janssen YM, Van Houten B, Borm PJ, Mossman BT. Cell and tissue responses to oxidative damage. Lab Invest. 1993;69:261–274.
  54. Iwanaga M, Mori K, Iida T, Urata Y, Matsuo T, et al. Nuclear factor kappa B dependent induction of gamma glutamylcysteine synthetase by ionizing radiation in T98G human glioblastoma cells. Free Radic Biol Med. 1998;24:1256–1268.
  55. Stohs SJ, Bagchi D. Oxidative mechanisms in the toxicity of metal ions. Free Radic Biol Med. 1995;18:321–336.
  56. Leonard SS, Harris GK, Shi X. Metal-induced oxidative stress and signal transduction. Free Radic Biol Med. 2004;37:1921–1942.
  57. Shi H, Shi X, Liu KJ. Oxidative mechanism of arsenic toxicity and carcinogenesis. Mol Cell Biochem. 2004;255:67–78.
  58. Pi J, Horiguchi S, Sun Y, Nikaido M, Shimojo N, Hayashi T. A potential mechanism for the impairment of nitric oxide formation caused by prolonged oral exposure to arsenate in rabbits. Free Radic Biol Med.2003;35:102–113.
  59. Rin K, Kawaguchi K, Yamanaka K, Tezuka M, Oku N, Okada S. DNAstrand breaks induced by dimethylarsinic acid, a metabolite of inorganic arsenics, are strongly enhanced by superoxide anion radicals. Biol Pharm Bull. 1995;18:45–58.
  60. Waalkes MP, Liu J, Ward JM, Diwan LA. Mechanisms underlying arsenic carcinogenesis: hypersensitivity of mice exposed to inorganic arsenic during gestation. Toxicology. 2004;198:31–38.
  61. Schiller CM, Fowler BA, Woods JS. Effects of arsenic on pyruvate dehydrogenase activation. Environ Health Perspect. 1977;19:205–207.
  62. Monterio HP, Bechara EJH, Abdalla DSP. Free radicals involvement in neurological porphyrias and lead poisoning. Mol Cell Biochem. 1991;103:73–83.
  63. Tripathi RM, Raghunath R, Mahapatra S. Blood lead and its effect on Cd, Cu, Zn, Fe and hemoglobin levels of children. Sci Total Environ. 2001;277:161–168.
  64. Nehru B, Dua R. The effect of dietary selenium on lead neurotoxicity. J Environ Pathol Toxicol Oncol. 1997;16:47–50.
  65. Reid TM, Feig DI, Loeb LA. Mutagenesis by metal-induced oxygen radicals. Environ Health Perspect. 1994;102(suppl 3):57–61.
  66. Kinnula VL, Crapo JD. Superoxide dismutases in the lung and human lung diseases. Am J Respir Crit Care Med. 2003;167:1600–1619.
  67. Kinnula VL. Production and degradation of oxygen metabolites during inflammatory states in the human lung. Curr Drug Targets Inflamm Allergy. 2005;4:465–470.

  68. Zelko IN, Mariani TJ, Folz RJ. Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression. Free Radic Biol Med. 2002;33:337–349.

  69. Kirkman HN, Rolfo M, Ferraris AM, Gaetani GF. Mechanisms of protection of catalase by NADPH. Kinetics and stoichiometry. J Biol Chem. 1999;274:13908–13914.
  70. Flohé L. Glutathione peroxidase. Basic Life Sci. 1988;49:663–668.
  71. Arthur JR. The glutathione peroxidases. Cell Mol Life Sci. 2000;57:1825–1835.
  72. Chu FF, Doroshow JH, Esworthy RS. Expression, characterization, and tissue distribution of a new cellular selenium-dependent glutathione peroxidase, GSHPx-GI. J Biol Chem. 1993;268:2571–2576.
  73. Comhair SA, Bhathena PR, Farver C, Thunnissen FB, Erzurum SC. Extracellular glutathione peroxidase induction in asthmatic lungs: evidence for redox regulation of expression in human airway epithelial cells. FASEB J. 2001;15:70–78.
  74. Gromer S, Urig S, Becker K. The thioredoxin systemdfrom science to clinic. Med Res Rev. 2004;24:40–89.
  75. Kinnula VL, Lehtonen S, Kaarteenaho-Wiik R, Lakari E, Pääkkö P, et al. Cell specific expression of peroxiredoxins in human lung and pulmonary sarcoidosis. Thorax. 2002;57:157–164.
  76. Dubuisson M, Vander Stricht D, Clippe A, Etienne F, Nauser T, et al. Human peroxiredoxin 5 is a peroxynitrite reductase. FEBS Lett. 2004;571:161–165.
  77. Holmgren A. Antioxidant function of thioredoxin and glutaredoxin systems. Antioxid Redox Signal. 2000;2:811–820.
  78. Dickinson DA, Forman HJ. Glutathione in defense and signaling: lessons from a small thiol. Ann N Y Acad Sci. 2002;973:488–504.
  79. Sies H. Glutathione and its role in cellular functions. Free Radic Biol Med. 1999;27:916–921.
  80. Ladner JE, Parsons JF, Rife CL, Gilliland GL, Armstrong RN. Parallel evolutionary pathways for glutathione transferases: structure and mechanism of the mitochondrial class kappa enzyme rGSTK1-1. Biochemistry. 2004;43:52–61.
  81. Robinson A, Huttley GA, Booth HS, Board PG. Modelling and bioinformatics studies of the human kappa class glutathione transferase predict a novel third transferase family with homology to prokaryotic 2-hydroxychromene-2-carboxylate isomerases. Biochem J. 2004;379:541–552.
  82. Jakobsson P-J, Morgenstern R, Mancini J, Ford-Hutchinson A, Persson B. Common structural features of MAPEGda widespread superfamily of membrane associated proteins with highly divergent functions in eicosanoid and glutathione metabolism. Protein Sci. 1999;8:689–692.
  83. Hayes JD, Pulford DJ. The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Crit Rev Biochem Mol Biol. 1995;30:445–600.
  84. Armstrong RN. Structure, catalytic mechanism, and evolution of the glutathione transferases. Chem Res Toxicol. 1997;10:2–18.
  85. Hayes JD, McLellan LI. Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress. Free Radic Res. 1999;31:273–300.
  86. Sheehan D, Meade G, Foley VM, Dowd CA. Structure, function and evolution of glutathione transferases: implications for classification of nonmammalian members of an ancient enzyme superfamily. Biochem J. 2001;360:1–16.
  87. Cho S-G, Lee YH, Park H-S, Ryoo K, Kang KW, et al. Glutathione S-transferase Mu modulates the stress activated signals by suppressing apoptosis signal-regulating kinase 1. J Biol Chem. 2001;276:12749–12755.
  88. Dorion S, Lambert H, Landry J. Activation of the p38 signaling pathway by heat shock involves the dissociation of glutathione S-transferase Mu from Ask1. J Biol Chem. 2002;277:30792–30797.
  89. Adler V, Yin Z, Fuchs SY, Benezra M, Rosario L, et al. Regulation of JNK signalling by GSTp. EMBO J. 1999;18:1321–1334.
  90. Manevich Y, Feinstein SI, Fisher AB. Activation of the antioxidant enzyme 1-CYS peroxiredoxin requires glutathionylation mediated by heterodimerization with pGST. Proc Natl Acad Sci U S A. 2004;101:3780–3785.
  91. Bunker VW. Free radicals, antioxidants and ageing. Med Lab Sci. 1992;49:299–312.
  92. Mezzetti A, Lapenna D, Romano F, Costantini F, Pierdomenico SD, et al. Systemic oxidative stress and its relationship with age and illness. J Am Geriatr Soc. 1996;44:823–827.
  93. White E, Shannon JS, Patterson RE. Relationship between vitamin and
    calcium supplement use and colon cancer. Cancer Epidemiol Biomarkers Prev. 1997;6:769–774.
  94. Masella R, Di Benedetto R, Vari R, Filesi C, Giovannini C. Novel mechanisms of natural antioxidant compounds in biological systems: involvement of glutathione and glutathione-related enzymes. J Nutr Biochem. 2005;16:577–586.
  95. Curello S, Ceconi C, Bigoli C, Ferrari R, Albertini A, Guarnieri C. Changes in the cardiac glutathione status after ischemia and reperfusion. Experientia. 1985;41:42–43.
  96. El-Agamey A, Lowe GM, McGarvey DJ, Mortensen A, Phillip DM, Truscott TG. Carotenoid radical chemistry and antioxidant/pro-oxidant properties. Arch Biochem Biophys. 2004;430:37–48.
  97. Rice-Evans CA, Sampson J, Bramley PM, Holloway DE. Why do we expect carotenoids to be antioxidants in vivo? Free Radic Res. 1997;26:381–398.
  98. Niles RM. Signaling pathways in retinoid chemoprevention and treatment of cancer. Mutat Res. 2004;555:81–96.
  99. Donato LJ, Noy N. Suppression of mammary carcinoma growth by retinoic acid: proapoptotic genes are targets for retinoic acid receptor and cellular retinoic acid-binding protein II signaling. Cancer Res. 2005;65:8193–8199.
  100. Niizuma H, Nakamura Y, Ozaki T, Nakanishi H, Ohira M, et al. Bcl-2 is a key regulator for the retinoic acid-induced apoptotic cell death in neuroblastoma. Oncogene. 2006;25:5046–5055.
  101. Dalton TP, Shertzer HG, Puga A. Regulation of gene expression by reactive oxygen. Ann Rev Pharmacol Toxicol. 1999;39:67–101.
  102. Scandalios JG. Genomic responses to oxidative stress. In: Meyers RA, ed. Encyclopedia of Molecular Cell Biology and Molecular Medicine. Vol 5. 2nd ed. Weinheim, Germany: Wiley-VCH; 2004: 489–512.
  103. Ghosh R, Mitchell DL. Effect of oxidative DNA damage in promoter elements on transcription factor binding. Nucleic Acids Res. 1999;27:3213–3218.
  104. Marietta C, Gulam H, Brooks PJ. A single 8, 50-cyclo-20-deoxyadenosine lesion in a TATA box prevents binding of the TATA binding protein and strongly reduces transcription in vivo. DNA Repair (Amst). 2002;1:967–975.
  105. Jackson AL, Chen R, Loeb LA. Induction of microsatellite instability
    by oxidative DNA damage. Proc Natl Acad Sci U S A. 1998;95:12468–12473.
  106. Caldecott KW. Protein-protein interactions during mammalian DNA single-strand break repair. Biochem Soc Trans. 2003;31:247–251.
  107. Cooke MS, Evans MD, Dizdaroglu M, Lunec J. Oxidative DNA damage: mechanisms, mutation, and disease. FASEB J. 2003;17:1195–1214.
  108. Jones PL, Wolffe AP. Relationships between chromatin organization and DNA methylation in determining gene expression. Semin Cancer Biol. 1999;9:339–347.
  109. Girotti AW. Mechanisms of lipid peroxidation. J Free Radic Biol Med. 1985;1:87–95.
  110. Siu GM, Draper HH. Metabolism of malonaldehyde in vivo and in vitro. Lipids. 1982;17:349–355.
  111. Esterbauer H, Koller E, Slee RG, Koster JF. Possible involvement of the lipid-peroxidation product 4-hydroxynonenal in the formation of fluorescent chromolipids. Biochem J. 1986;239:405–409.
  112. Hagihara M, Nishigaki I, Maseki M, Yagi K. Age-dependent changes in lipid peroxide levels in the lipoprotein fractions of human serum. J Gerontol. 1984;39:269–272.
  113. Keller JN, Mark RJ, Bruce AJ, Blanc E, Rothstein JD, et al. 4- Hydroxynonenal, an aldehydic product of membrane lipid peroxidation, impairs glutamate transport and mitochondrial function in synaptosomes. Neuroscience. 1997;806:85–96.
  114. Uchida K, Shiraishi M, Naito Y, Torii Y, Nakamura Y, Osawa T. Activation of stress signaling pathways by the end product of lipid peroxidation. 4-hydroxy-2-nonenal is a potential inducer of intracellular peroxide production. J Biol Chem. 1999;274:2234–2242.
  115. Suc I, Meilhac O, Lajoie-Mazenc I, Vandaele J, Jurgens G, Salvayre R, Negre-Salvayre A. Activation of EGF receptor by oxidized LDL. FASEB J. 1998;12:665–671.

  116. Tsukagoshi H, Kawata T, Shimizu Y, Ishizuka T, Dobashi K, Mori M. 4-Hydroxy-2-nonenal enhances fibronectin production by IMR-90 human lung fibroblasts partly via activation of epidermal growth factor receptor-linked extracellular signal-regulated kinase p44/42 pathway. Toxicol Appl Pharmacol. 2002;184:127–135.

  117. Montuschi P, Collins JV, Ciabattoni G, Lazzeri N, Corradi M, Kharitonov SA, Barnes PJ. Exhaled 8-isoprostane as an in vivo biomarker of lung oxidative stress in patients with COPD and healthy smokers. Am J Respir Crit Care Med. 2000;162:1175–1177.
  118. Morrison D, Rahman I, Lannan S, MacNee W. Epithelial permeability, inflammation, and oxidant stress in the air spaces of smokers. Am J Respir Crit Care Med. 1999;159:473–479.
  119. Nowak D, Kasielski M, Antczak A, Pietras T, Bialasiewicz P. Increased content of thiobarbituric acid-reactive substances and hydrogen peroxide in the expired breath condensate of patients with stable chronic obstructive pulmonary disease: no significant effect of cigarette smoking. Respir Med. 1999;93:389–396.
  120. Kelly FJ, Mudway IS. Protein oxidation at the air-lung interface. Amino Acids. 2003;25:375–396.
  121. Dean RT, Roberts CR, Jessup W. Fragmentation of extracellular and intracellular polypeptides by free radicals. Prog Clin Biol Res. 1985;180:341–350.
  122. Keck RG. The use of t-butyl hydroperoxide as a probe for methionine oxidation in proteins. Anal Biochem. 1996;236:56–62.
  123. Davies KJ. Protein damage and degradation by oxygen radicals. I. General aspects. J Biol Chem. 1987;262:9895–9901.
  124. Stadtman ER. Metal ion-catalyzed oxidation of proteins: biochemical mechanism and biological consequences. Free Radic Biol Med.
    1990;9:315–325.
  125. Fucci L, Oliver CN, Coon MJ, Stadtman ER. Inactivation of key metabolic enzymes by mixed-function oxidation reactions: possible implication in protein turnover and ageing. Proc Natl Acad Sci U S A. 1983;80:1521–1525.
  126. Stadtman ER, Moskovitz J, Levine RL. Oxidation of methionine residues of proteins: biological consequences. Antioxid Redox Signal. 2003;5:577–582.
  127. Stadtman ER, Levine RL. Free radical-mediated oxidation of free amino acids and amino acid residues in proteins. Amino Acids. 2003;25:207–218.
  128. Stadtman ER. Protein oxidation in aging and age-related diseases. Ann N Y Acad Sci. 2001;928:22–38.
  129. Shacter E. Quantification and significance of protein oxidation in biological samples. Drug Metab Rev. 2000;32:307–326.
  130. Poli G, Leonarduzzi G, Biasi F, Chiarpotto E. Oxidative stress and cell signalling. Curr Med Chem. 2004;11:1163–1182.
  131. Neufeld G, Cohen T, Gengrinovitch S, Poltorak Z. Vascular endothelial growth factor (VEGF) and its receptors. FASEB J. 1999;13:9–22.
  132. Sundaresan M, Yu ZX, Ferrans VJ, Sulciner DJ, Gutkind JS, et al. Regulation of reactive-oxygen species generation in fibroblasts by Rac1. Biochem J. 1996;318:379–382.
  133. Sun T, Oberley LW. Redox regulation of transcriptional activators. Free Radic Biol Med. 1996;21:335–348.
  134. Klatt P, Molina EP, De Lacoba MG, Padilla CA, Martinez-Galesteo E, Barcena JA, Lamas S. Redox regulation of c-Jun DNA binding by reversible S-glutathiolation. FASEB J. 1999;13:1481–1490.
  135. Reynaert NL, Ckless K, Guala AS, Wouters EF, van der Vliet A, Janssen Heininger
    YM. In situ detection of S-glutathionylated proteins following glutaredoxin-1 catalyzed cysteine derivatization. Biochim Biophys Acta. 2006;1760:380–387.
  136. Reynaert NL, Wouters EF, Janssen-Heininger YM. Modulation of glutaredoxin-1
    expression in a mouse model of allergic airway disease. Am J Respir Cell Mol Biol. 2007;36:147–151.
  137. Filomeni G, Rotilio G, Ciriolo MR. Cell signalling and the glutathione redox system. Biochem Pharmacol. 2002;64:1057–1064.
  138. Pande V, Ramos MJ. Molecular recognition of 15-deoxydelta (12,14) prostaglandin J(2) by nuclear factor-kappa B and other cellular proteins. Bioorg Med Chem Lett. 2005;15:4057–4063.
  139. Perkins ND. Integrating cell-signalling pathways with NF-kappaB and IKK function. Nat Rev Mol Cell Biol. 2007;8:49–62.
  140. Gilmore TD. Introduction to NF-kappaB: players, pathways, perspectives. Oncogene. 2006;25:6680–6684.
  141. Hirota K, Murata M, Sachi Y, Nakamura H, Takeuchi J, Mori K, Yodoi J. Distinct roles of thioredoxin in the cytoplasm and in the nucleus. A two-step mechanism of redox regulation of transcription factor NF-kappaB. J Biol Chem. 1999;274:27891–27897.
  142. Ward PA. Role of complement, chemokines and regulatory cytokines in acute lung injury. Ann N Y Acad Sci. 1996;796:104–112.
  143. Akira S, Kishimoto A. NF-IL6 and NF-kB in cytokine gene regulation. Adv Immunol. 1997;65:1–46.
  144. Meyer M, Schreck R, Baeuerle PA. H2O2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor. EMBO J. 1993;12:2005–2015.
  145. Abate C, Patel L, Rausher FJ, Curran T. Redox regulation of fos and jun DNA-binding activity in vitro. Science. 1990;249:1157–1161.
  146. Galter D, Mihm S, Droge W. Distinct effects of glutathione disulphide on the nuclear transcription factors kB and the activator protein-1. Eur J Biochem. 1994;221:639–648.
  147. Hirota K, Matsui M, Iwata S, Nishiyama A, Mori K, Yodoi J. AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1. Proc Natl Acad Sci U S A. 1997;94: 3633–3638.
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The Functional Fitness Fellas | What is it? & Who Are They?

Dr. Alexander Jimenez 111 views May 17, 2020 2:46 pm

PODCAST: Dr. Alex Jimenez, a chiropractor in El Paso, TX, Kenna Vaughn, and Astrid Ornelas discuss a variety of natural treatment methods and techniques in treating inflammation as the primary focus of this podcast video. Dr. Alex Jimenez, Kenna Vaughn, and Astrid Ornelas present a discussion of natural ways to treat inflammatory cascades, including nutrition, diet, and nutraceuticals, among others. Knowing what are the best supplements are also presented as the primary focus of this podcast video. Nutraceuticals are considered to be a safe and effective alternative treatment approach that is well researched by scientists to help promote health and wellness. - Podcast Insight

If you have enjoyed this video and/or we have helped you in any way please feel free to subscribe and share us. 

Thank You & God Bless.   
Dr. Alex Jimenez DC, MSACP, ATN, IFMCP. CIFM, CCST

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Sports Page: https://www.facebook.com/pushasrx/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/
Facebook Fitness Center Page: https://www.facebook.com/justplayfitness

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: 
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Rehabilitation Center: https://www.pushasrx.com
Functional Medicine: https://wellnessdoctorrx.com
- 

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

PODCAST: Dr. Alex Jimenez, a chiropractor in El Paso, TX, Kenna Vaughn, and Astrid Ornelas discuss a variety of natural treatment methods and techniques in treating inflammation as the primary focus of this podcast video. Dr. Alex Jimenez, Kenna Vaughn, and Astrid Ornelas present a discussion of natural ways to treat inflammatory cascades, including nutrition, diet, and nutraceuticals, among others. Knowing what are the best supplements are also presented as the primary focus of this podcast video. Nutraceuticals are considered to be a safe and effective alternative treatment approach that is well researched by scientists to help promote health and wellness. - Podcast Insight

If you have enjoyed this video and/or we have helped you in any way please feel free to subscribe and share us.

Thank You & God Bless.
Dr. Alex Jimenez RN, DC, MSACP, CCST

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Sports Page: https://www.facebook.com/pushasrx/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/
Facebook Fitness Center Page: https://www.facebook.com/PUSHftinessathletictraining/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information:
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Rehabilitation Center: https://www.pushasrx.com
Functional Medicine: https://wellnessdoctorrx.com
Fitness & Nutrition: http://www.push4fitness.com/team/

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

9 0

YouTube Video UEwzeUg1RlctbFNNT2Fac3o4VGxxUE9rZW1PTUJYNUxxLS43QzNCNkZENzIyMDY2MjZB

Treating Inflammation Naturally | El Paso, Tx (2020)

Dr. Alexander Jimenez 178 views April 3, 2020 8:27 pm

Chronic back pain is a well-known health issue which unfortunately commonly affects many people throughout their lifetime. From chronic neck pain and back pain to widespread chronic pain symptoms associated with fibromyalgia, these painful symptoms can ultimately affect an individual's overall health and wellness as well as their quality of life. Dr. Alex Jimenez is a chiropractor, or doctor of chiropractic (DC), who focuses on the diagnosis, treatment, and prevention of a variety of health issues, including chronic pain. Patients tell their stories and describe how Dr. Alex Jimenez has helped them recover their overall quality of life as well as their health and wellness. The patients highly recommend Dr. Alex Jimenez as the non-surgical choice for chronic pain, among other health issues.  

If you have enjoyed this video and/or we have helped you in any way 
please feel free to subscribe and share us. 

Thank You & God Bless.   
Dr. Alex Jimenez DC, MSACP, ATN, IFMCP. CIFM, CCST

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Sports Page: https://www.facebook.com/pushasrx/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/
Facebook Fitness Center Page: https://www.facebook.com/justplayfitness

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: 
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Rehabilitation Center: https://www.pushasrx.com
Functional Medicine: https://wellnessdoctorrx.com
- 

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

Chronic back pain is a well-known health issue which unfortunately commonly affects many people throughout their lifetime. From chronic neck pain and back pain to widespread chronic pain symptoms associated with fibromyalgia, these painful symptoms can ultimately affect an individual's overall health and wellness as well as their quality of life. Dr. Alex Jimenez is a chiropractor, or doctor of chiropractic (DC), who focuses on the diagnosis, treatment, and prevention of a variety of health issues, including chronic pain. Patients tell their stories and describe how Dr. Alex Jimenez has helped them recover their overall quality of life as well as their health and wellness. The patients highly recommend Dr. Alex Jimenez as the non-surgical choice for chronic pain, among other health issues.

If you have enjoyed this video and/or we have helped you in any way
please feel free to subscribe and share us.

Thank You & God Bless.
Dr. Alex Jimenez RN, DC, MSACP, CCST

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Sports Page: https://www.facebook.com/pushasrx/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/
Facebook Fitness Center Page: https://www.facebook.com/PUSHftinessathletictraining/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information:
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Rehabilitation Center: https://www.pushasrx.com
Functional Medicine: https://wellnessdoctorrx.com
Fitness & Nutrition: http://www.push4fitness.com/team/

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

0 0

YouTube Video UEwzeUg1RlctbFNNT2Fac3o4VGxxUE9rZW1PTUJYNUxxLS4zMUEyMkQwOTk0NTg4MDgw

Chronic *BACK PAIN* Therapy | El Paso, Tx (2019)

Dr. Alexander Jimenez 69 views June 14, 2019 4:51 pm

Sciatica, or sciatic nerve pain, is a common health issue which can affect approximately 8 out of 10 people throughout their lifetimes. Patients describe how their back pain affected their ability to engage in their everyday physical activities. Truide Torres discusses how she struggled with back pain during her pregnancy. Dionicio Espinoza discusses how his job as a truck driver can trigger his back pain. Patients recommend chiropractic care with Dr. Alex Jimenez, DC, in El Paso, TX, to treat sciatica, or sciatic nerve pain, and back pain.

If you have enjoyed this video and/or we have helped you in any way 
please feel free to subscribe and share us. 

Thank You & God Bless.   
Dr. Alex Jimenez DC, MSACP, ATN, IFMCP. CIFM, CCST

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Sports Page: https://www.facebook.com/pushasrx/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/
Facebook Fitness Center Page: https://www.facebook.com/justplayfitness

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: 
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Rehabilitation Center: https://www.pushasrx.com
Functional Medicine: https://wellnessdoctorrx.com
- 

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

Sciatica, or sciatic nerve pain, is a common health issue which can affect approximately 8 out of 10 people throughout their lifetimes. Patients describe how their back pain affected their ability to engage in their everyday physical activities. Truide Torres discusses how she struggled with back pain during her pregnancy. Dionicio Espinoza discusses how his job as a truck driver can trigger his back pain. Patients recommend chiropractic care with Dr. Alex Jimenez, DC, in El Paso, TX, to treat sciatica, or sciatic nerve pain, and back pain.

If you have enjoyed this video and/or we have helped you in any way
please feel free to subscribe and share us.

Thank You & God Bless.
Dr. Alex Jimenez RN, DC, MSACP, CCST

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Sports Page: https://www.facebook.com/pushasrx/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/
Facebook Fitness Center Page: https://www.facebook.com/PUSHftinessathletictraining/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information:
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Rehabilitation Center: https://www.pushasrx.com
Functional Medicine: https://wellnessdoctorrx.com
Fitness & Nutrition: http://www.push4fitness.com/team/

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

0 0

YouTube Video UEwzeUg1RlctbFNNT2Fac3o4VGxxUE9rZW1PTUJYNUxxLS5CQkEwRDA0MDkwNUM2MDY1

The *SCIATICA* Specialist | El Paso, Tx (2019)

Dr. Alexander Jimenez 240 views May 24, 2019 4:56 pm

April Hermosillo achieves overall health and wellness every day by following proper nutrition and engaging in exercises or physical activities. As a regular fitness participant, however, April Hermosillo can experience back and low back pain which ultimately affects even her most basic daily tasks. April Hermosillo struggled with spine health issues and sciatica before she received chiropractic care. Dr. Alex Jimenez is a chiropractor in El Paso, TX who has helped April Hermosillo achieve pain relief so she can return to her everyday fitness routines. April Hermosillo describes how Dr. Alex Jimenez has tremendously helped improve her overall symptoms. April Hermosillo highly recommends Dr. Alex Jimenez as the non-surgical choice for personalized spine and sciatica treatment and rehabilitation.

If you have enjoyed this video and/or we have helped you in any way 
please feel free to subscribe and share us. 

Thank You & God Bless.   
Dr. Alex Jimenez DC, MSACP, ATN, IFMCP. CIFM, CCST

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Sports Page: https://www.facebook.com/pushasrx/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/
Facebook Fitness Center Page: https://www.facebook.com/justplayfitness

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: 
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Rehabilitation Center: https://www.pushasrx.com
Functional Medicine: https://wellnessdoctorrx.com
- 

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

April Hermosillo achieves overall health and wellness every day by following proper nutrition and engaging in exercises or physical activities. As a regular fitness participant, however, April Hermosillo can experience back and low back pain which ultimately affects even her most basic daily tasks. April Hermosillo struggled with spine health issues and sciatica before she received chiropractic care. Dr. Alex Jimenez is a chiropractor in El Paso, TX who has helped April Hermosillo achieve pain relief so she can return to her everyday fitness routines. April Hermosillo describes how Dr. Alex Jimenez has tremendously helped improve her overall symptoms. April Hermosillo highly recommends Dr. Alex Jimenez as the non-surgical choice for personalized spine and sciatica treatment and rehabilitation.

If you have enjoyed this video and/or we have helped you in any way
please feel free to subscribe and share us.

Thank You & God Bless.
Dr. Alex Jimenez RN, DC, MSACP, CCST

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Sports Page: https://www.facebook.com/pushasrx/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/
Facebook Fitness Center Page: https://www.facebook.com/PUSHftinessathletictraining/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information:
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Rehabilitation Center: https://www.pushasrx.com
Functional Medicine: https://wellnessdoctorrx.com
Fitness & Nutrition: http://www.push4fitness.com/team/

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

1 0

YouTube Video UEwzeUg1RlctbFNNT2Fac3o4VGxxUE9rZW1PTUJYNUxxLS42Qzk5MkEzQjVFQjYwRDA4

Personalized *SPINE & SCIATICA* Treatment | El Paso, Tx (2019)

Dr. Alexander Jimenez 126 views March 29, 2019 1:21 pm

Sciatica is a collection of symptoms characterized by pain which extends down the length of the legs from the lower back. Approximately 90 percent of sciatica, or sciatic nerve pain, develops when a spinal disc herniation compresses a spinal nerve along the lumbar spine. Piriformis syndrome and pregnancy are other common causes of sciatica. Chiropractic care is an alternative, treatment option which focuses on the treatment of injuries and/or conditions associated with the musculoskeletal and nervous system. Patients describe how Dr. Alex Jimenez has helped them achieve sciatica relief through chiropractic care. Edgar M. Reyes and Truide Torres highly recommend Dr. Alex Jimenez as the non-surgical choice for sciatica.

If you have enjoyed this video and/or we have helped you in any way please feel free to subscribe and share us.  

Thank You & God Bless.    
Dr. Alex Jimenez DC, MSACP, ATN, IFMCP. CIFM, CCST 

Subscribe: http://bit.ly/drjyt 

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/ 
Facebook Sports Page: https://www.facebook.com/pushasrx/ 
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/ 
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/ 
Facebook Fitness Center Page: https://www.facebook.com/justplayfitness 

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2 
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ 

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/ 

Information:  
Clinical Site: https://www.dralexjimenez.com 
Injury Site: https://personalinjurydoctorgroup.com 
Sports Injury Site: https://chiropracticscientist.com 
Back Injury Site: https://www.elpasobackclinic.com 
Rehabilitation Center: https://www.pushasrx.com 
Functional Medicine: https://wellnessdoctorrx.com 
-  

Twitter: https://twitter.com/dralexjimenez 
Twitter: https://twitter.com/crossfitdoctor

Sciatica is a collection of symptoms characterized by pain which extends down the length of the legs from the lower back. Approximately 90 percent of sciatica, or sciatic nerve pain, develops when a spinal disc herniation compresses a spinal nerve along the lumbar spine. Piriformis syndrome and pregnancy are other common causes of sciatica. Chiropractic care is an alternative, treatment option which focuses on the treatment of injuries and/or conditions associated with the musculoskeletal and nervous system. Patients describe how Dr. Alex Jimenez has helped them achieve sciatica relief through chiropractic care. Edgar M. Reyes and Truide Torres highly recommend Dr. Alex Jimenez as the non-surgical choice for sciatica.

If you have enjoyed this video and/or we have helped you in any way please feel free to subscribe and share us.

Thank You & God Bless.
Dr. Alex Jimenez RN, DC, MSACP, CCST

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Sports Page: https://www.facebook.com/pushasrx/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/
Facebook Fitness Center Page: https://www.facebook.com/PUSHftinessathletictraining/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information:
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Rehabilitation Center: https://www.pushasrx.com
Functional Medicine: https://wellnessdoctorrx.com
Fitness & Nutrition: http://www.push4fitness.com/team/

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

0 0

YouTube Video UEwzeUg1RlctbFNNT2Fac3o4VGxxUE9rZW1PTUJYNUxxLS4zMEQ1MEIyRTFGNzhDQzFB

Advanced Sciatica Treatment | El Paso, Tx (Chiropractor)

Dr. Alexander Jimenez 42 views March 22, 2019 4:17 pm

Truide Torres recibe atención quiropráctica con el Dr. Alex Jimenez por su dolor en el nervio ciático. La ciática es una colección de síntomas caracterizados por dolor lumbar que se irradia a través de los muslos hacia las piernas, rodillas y pies. El dolor del nervio ciático puede afectar uno o ambos lados de las extremidades inferiores. Truide Torres luchó para participar en sus actividades físicas diarias debido a sus síntomas de ciática. A través de ajustes espinales y manipulaciones manuales, el Dr. Alex Jimenez restauró cuidadosamente la alineación original de su columna, aliviando sus síntomas dolorosos. Truide Torres recomienda al Dr. Alex Jimenez y su personal como la opción no quirúrgica para la ciática.

Recomiéndanos: Si te ha gustado este video y / o te hemos ayudado de alguna manera, no dudes en recomendarnos. Gracias, Dios te bendiga.

Recommend: Dr. Alex Jimenez – Chiropractor 
Health Grades: http://www.healthgrades.com/review/3SDJ4 
Facebook Clinical Page: https://www.facebook.com/dralexjimenez/reviews/ 
Facebook Sports Page: https://www.facebook.com/pushasrx/ 
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/ 
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/ 
Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2 
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ 

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/ 

Information: Dr. Alex Jimenez – Chiropractor 
Clinical Site: https://www.dralexjimenez.com 
Injury Site: https://personalinjurydoctorgroup.com 
Sports Injury Site: https://chiropracticscientist.com 
Back Injury Site: https://www.elpasobackclinic.com 

Pinterest: https://www.pinterest.com/dralexjimenez/ 
Twitter: https://twitter.com/dralexjimenez 
Twitter: https://twitter.com/crossfitdoctor 

Recommend: PUSH-as-Rx ®™ 
Rehabilitation Center: https://www.pushasrx.com 
Facebook: https://www.facebook.com/justplayfitness 
PUSH-as-Rx: www.pushasrx.com

Truide Torres recibe atención quiropráctica con el Dr. Alex Jimenez por su dolor en el nervio ciático. La ciática es una colección de síntomas caracterizados por dolor lumbar que se irradia a través de los muslos hacia las piernas, rodillas y pies. El dolor del nervio ciático puede afectar uno o ambos lados de las extremidades inferiores. Truide Torres luchó para participar en sus actividades físicas diarias debido a sus síntomas de ciática. A través de ajustes espinales y manipulaciones manuales, el Dr. Alex Jimenez restauró cuidadosamente la alineación original de su columna, aliviando sus síntomas dolorosos. Truide Torres recomienda al Dr. Alex Jimenez y su personal como la opción no quirúrgica para la ciática.

Recomiéndanos: Si te ha gustado este video y / o te hemos ayudado de alguna manera, no dudes en recomendarnos. Gracias, Dios te bendiga.

Recommend: Dr. Alex Jimenez – Chiropractor
Health Grades: http://www.healthgrades.com/review/3SDJ4
Facebook Clinical Page: https://www.facebook.com/dralexjimenez/reviews/
Facebook Sports Page: https://www.facebook.com/pushasrx/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/
Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: Dr. Alex Jimenez – Chiropractor
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com

Pinterest: https://www.pinterest.com/dralexjimenez/
Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

Recommend: PUSH-as-Rx ®™
Rehabilitation Center: https://www.pushasrx.com
Facebook: https://www.facebook.com/PUSHftinessathletictraining/
PUSH-as-Rx: http://www.push4fitness.com/team/

0 0

YouTube Video UEwzeUg1RlctbFNNT2Fac3o4VGxxUE9rZW1PTUJYNUxxLS40QzRDOEU0QUYwNUIxN0M1

Tratamiendo para dolor de nervio Ciático | El Paso, Tx

Dr. Alexander Jimenez 97 views December 17, 2018 12:44 pm

Sciatica is a collection of symptoms characterized by pain, discomfort, tingling and burning sensations, and numbness which often extends from the low back, down the buttocks and thighs, into the knee and the foot. Sciatica is caused by the compression of the sciatic nerve, the largest and longest nerve in the human body. Sciatic nerve pain can develop due to an injury and/or aggravated condition. Patients diagnosed with sciatica describe their symptoms and how these affected their daily lives. Dr. Alex Jimenez and his staff have provided pain relief to many patients experiencing sciatica. Chiropractic care can help restore the original alignment of the spine to help improve sciatica. Dr. Alex Jimenez is the non-surgical choice for a variety of health issues, including sciatica, or sciatic nerve pain.

Please Recommend Us: If you have enjoyed this video and/or we have helped you in any way please feel free to recommend us. Thank You & God Bless.  

Recommend: Dr. Alex Jimenez – Chiropractor 
Health Grades: http://www.healthgrades.com/review/3SDJ4 
Facebook Clinical Page: https://www.facebook.com/dralexjimenez/reviews/ 
Facebook Sports Page: https://www.facebook.com/pushasrx/ 
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/ 
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/ 
Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2 
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ 

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/ 

Information: Dr. Alex Jimenez – Chiropractor 
Clinical Site: https://www.dralexjimenez.com 
Injury Site: https://personalinjurydoctorgroup.com 
Sports Injury Site: https://chiropracticscientist.com 
Back Injury Site: https://www.elpasobackclinic.com 

Pinterest: https://www.pinterest.com/dralexjimenez/ 
Twitter: https://twitter.com/dralexjimenez 
Twitter: https://twitter.com/crossfitdoctor 

Recommend: PUSH-as-Rx ®™ 
Rehabilitation Center: https://www.pushasrx.com 
Facebook: https://www.facebook.com/justplayfitness 
PUSH-as-Rx: www.pushasrx.com

Sciatica is a collection of symptoms characterized by pain, discomfort, tingling and burning sensations, and numbness which often extends from the low back, down the buttocks and thighs, into the knee and the foot. Sciatica is caused by the compression of the sciatic nerve, the largest and longest nerve in the human body. Sciatic nerve pain can develop due to an injury and/or aggravated condition. Patients diagnosed with sciatica describe their symptoms and how these affected their daily lives. Dr. Alex Jimenez and his staff have provided pain relief to many patients experiencing sciatica. Chiropractic care can help restore the original alignment of the spine to help improve sciatica. Dr. Alex Jimenez is the non-surgical choice for a variety of health issues, including sciatica, or sciatic nerve pain.

Please Recommend Us: If you have enjoyed this video and/or we have helped you in any way please feel free to recommend us. Thank You & God Bless.

Recommend: Dr. Alex Jimenez – Chiropractor
Health Grades: http://www.healthgrades.com/review/3SDJ4
Facebook Clinical Page: https://www.facebook.com/dralexjimenez/reviews/
Facebook Sports Page: https://www.facebook.com/pushasrx/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/
Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: Dr. Alex Jimenez – Chiropractor
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com

Pinterest: https://www.pinterest.com/dralexjimenez/
Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

Recommend: PUSH-as-Rx ®™
Rehabilitation Center: https://www.pushasrx.com
Facebook: https://www.facebook.com/PUSHftinessathletictraining/
PUSH-as-Rx: http://www.push4fitness.com/team/

0 0

YouTube Video UEwzeUg1RlctbFNNT2Fac3o4VGxxUE9rZW1PTUJYNUxxLS5DNkMwRUI2MkI4QkI4NDFG

Rehabilitation for Sciatica Pain | El Paso, Tx.

Dr. Alexander Jimenez 46 views November 30, 2018 5:33 pm

A common health issue frequently treated by Dr. Alex Jimenez, sciatica is a collection of symptoms caused by the compression or impingement of the sciatic nerve, the largest and longest nerve in the human body. The most common symptoms of sciatica include low back pain, hip pain, and radiating pain which extends from the buttocks down into the feet. Dr. Alex Jimenez and his staff have helped many patients achieve pain relief from their sciatica symptoms through the use of a variety of treatment methods and techniques, educating them about their health issues. Dr. Alex Jimenez is the non-surgical choice for sciatic nerve pain. 

Please Recommend Us: If you have enjoyed this video and/or we have helped you in any way please feel free to recommend us. Thank You & God Bless.  

Recommend: Dr. Alex Jimenez – Chiropractor 
Health Grades: http://www.healthgrades.com/review/3SDJ4 
Facebook Clinical Page: https://www.facebook.com/dralexjimenez/reviews/ 
Facebook Sports Page: https://www.facebook.com/pushasrx/ 
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/ 
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/ 
Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2 
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ 

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/ 

Information: Dr. Alex Jimenez – Chiropractor 
Clinical Site: https://www.dralexjimenez.com 
Injury Site: https://personalinjurydoctorgroup.com 
Sports Injury Site: https://chiropracticscientist.com 
Back Injury Site: https://www.elpasobackclinic.com 

Pinterest: https://www.pinterest.com/dralexjimenez/ 
Twitter: https://twitter.com/dralexjimenez 
Twitter: https://twitter.com/crossfitdoctor 

Recommend: PUSH-as-Rx ®™ 
Rehabilitation Center: https://www.pushasrx.com 
Facebook: https://www.facebook.com/justplayfitness 
PUSH-as-Rx: www.pushasrx.com

A common health issue frequently treated by Dr. Alex Jimenez, sciatica is a collection of symptoms caused by the compression or impingement of the sciatic nerve, the largest and longest nerve in the human body. The most common symptoms of sciatica include low back pain, hip pain, and radiating pain which extends from the buttocks down into the feet. Dr. Alex Jimenez and his staff have helped many patients achieve pain relief from their sciatica symptoms through the use of a variety of treatment methods and techniques, educating them about their health issues. Dr. Alex Jimenez is the non-surgical choice for sciatic nerve pain.

Please Recommend Us: If you have enjoyed this video and/or we have helped you in any way please feel free to recommend us. Thank You & God Bless.

Recommend: Dr. Alex Jimenez – Chiropractor
Health Grades: http://www.healthgrades.com/review/3SDJ4
Facebook Clinical Page: https://www.facebook.com/dralexjimenez/reviews/
Facebook Sports Page: https://www.facebook.com/pushasrx/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/
Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: Dr. Alex Jimenez – Chiropractor
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com

Pinterest: https://www.pinterest.com/dralexjimenez/
Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

Recommend: PUSH-as-Rx ®™
Rehabilitation Center: https://www.pushasrx.com
Facebook: https://www.facebook.com/PUSHftinessathletictraining/
PUSH-as-Rx: http://www.push4fitness.com/team/

0 0

YouTube Video UEwzeUg1RlctbFNNT2Fac3o4VGxxUE9rZW1PTUJYNUxxLS4zQzFBN0RGNzNFREFCMjBE

Education About Sciatica | El Paso, Tx

Dr. Alexander Jimenez 91 views November 21, 2018 5:44 pm

Let's embark on a journey of holistic healing as we delve into the transformative realms of chiropractic care and functional medicine. Join us to uncover the secrets behind restoring vitality, enhancing well-being, and embracing a life of renewed health and vitality. Discover the synergistic power of ancient wisdom and modern science, guiding you towards optimal wellness and a vibrant life.

  Our care plans are base on Functional Medicine as a systems approach based on biology that focuses on identifying and addressing the root cause of disease. We focus on the paradigm that symptom or differential diagnosis may be one of many contributing factors to an individual's illness.   

This approach shifts from the traditional disease-centered focus of most medical practices to a more holistic person-centered approach.       

Our discussions team includes Integrative Doctors, Functional Medicine Experts, Nutritionists, Health Coaches, Chiropractors, Physical Medicine Doctors, Therapists, and Exercise Performance Specialists.       
We provide clinical insights, treatment options, and methods to achieve clinically sound, specific measured goals.*     

Functional & Integrative Health Live Events *   
✅ Stress Hormones & Health 
✅ Gut Health, Inflammation & Auto-Immunity* 
✅ Musculoskeletal Rehabilitation
✅ Fibromyalgia & Inflammation 
✅ Diabetes & Autoimmunity* 
✅ Weight Loss 
✅ Body Composition Analysis
✅ Thyroid Dysfunction* 
✅ Autoimmune Disorder*
✅ Heart Disease & Inflammation*
✅ Agility & Mobility 
✅ Injury Recovery Programs 
✅ Complex Lower Back Pain Recovery Plans 
✅ Severe Sciatica Syndromes 
✅ Other Complex Health Challenges
✅ Neutraceutical Recommendations
✅ Advanced Translational Nutrigenomics*
✅ Nutrigenomics, Proteomics, Metabalomics
✅ Care Plans (Advanced Clinical Practice) 
 
We present, bridge, and connect these various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.     

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.     

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.     

It is all about.   

LIVING, LOVING & MATTERING     

Join us in improving your health.     

Blessings,     

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone: 
phone: 915-850-0900   

Licensed in Texas & New Mexico*         

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.     

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.     

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.     
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*     

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: 
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com 

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

Let's embark on a journey of holistic healing as we delve into the transformative realms of chiropractic care and functional medicine. Join us to uncover the secrets behind restoring vitality, enhancing well-being, and embracing a life of renewed health and vitality. Discover the synergistic power of ancient wisdom and modern science, guiding you towards optimal wellness and a vibrant life.

Our care plans are base on Functional Medicine as a systems approach based on biology that focuses on identifying and addressing the root cause of disease. We focus on the paradigm that symptom or differential diagnosis may be one of many contributing factors to an individual's illness.

This approach shifts from the traditional disease-centered focus of most medical practices to a more holistic person-centered approach.

Our discussions team includes Integrative Doctors, Functional Medicine Experts, Nutritionists, Health Coaches, Chiropractors, Physical Medicine Doctors, Therapists, and Exercise Performance Specialists.
We provide clinical insights, treatment options, and methods to achieve clinically sound, specific measured goals.*

Functional & Integrative Health Live Events *
? Stress Hormones & Health
? Gut Health, Inflammation & Auto-Immunity*
? Musculoskeletal Rehabilitation
? Fibromyalgia & Inflammation
? Diabetes & Autoimmunity*
? Weight Loss
? Body Composition Analysis
? Thyroid Dysfunction*
? Autoimmune Disorder*
? Heart Disease & Inflammation*
? Agility & Mobility
? Injury Recovery Programs
? Complex Lower Back Pain Recovery Plans
? Severe Sciatica Syndromes
? Other Complex Health Challenges
? Neutraceutical Recommendations
? Advanced Translational Nutrigenomics*
? Nutrigenomics, Proteomics, Metabalomics
? Care Plans (Advanced Clinical Practice)

We present, bridge, and connect these various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.

It is all about.

LIVING, LOVING & MATTERING

Join us in improving your health.

Blessings,

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone:
phone: 915-850-0900

Licensed in Texas & New Mexico*

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information:
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

2 0

YouTube Video VVV5NTNGNC1RbUg3WVdEQ1NHUnF4T0VRLnB6Z3liZXYtUnB3

Unlocking Vitality: Chiropractic Wisdom and the Science of Functional Healing | El Paso, Tx (2024)

Dr. Alexander Jimenez 116 views May 7, 2024 2:37 pm

Join us for a fascinating journey through the world of personal injuries in this revealing video. We'll delve into the overlooked side of traumas and how they affect our bodies in ways we might not even realize. From ankle twists to lingering headaches, discover how untreated injuries can snowball into bigger health issues over time. Let's unravel the mysteries together and learn why it's crucial to address injuries early for better long-term health. 

 Our care plans are base on Functional Medicine as a systems approach based on biology that focuses on identifying and addressing the root cause of disease. We focus on the paradigm that symptom or differential diagnosis may be one of many contributing factors to an individual's illness.   

This approach shifts from the traditional disease-centered focus of most medical practices to a more holistic person-centered approach.       

Our discussions team includes Integrative Doctors, Functional Medicine Experts, Nutritionists, Health Coaches, Chiropractors, Physical Medicine Doctors, Therapists, and Exercise Performance Specialists.       
We provide clinical insights, treatment options, and methods to achieve clinically sound, specific measured goals.*     

Functional & Integrative Health Live Events *   
✅ Stress Hormones & Health 
✅ Gut Health, Inflammation & Auto-Immunity* 
✅ Musculoskeletal Rehabilitation
✅ Fibromyalgia & Inflammation 
✅ Diabetes & Autoimmunity* 
✅ Weight Loss 
✅ Body Composition Analysis
✅ Thyroid Dysfunction* 
✅ Autoimmune Disorder*
✅ Heart Disease & Inflammation*
✅ Agility & Mobility 
✅ Injury Recovery Programs 
✅ Complex Lower Back Pain Recovery Plans 
✅ Severe Sciatica Syndromes 
✅ Other Complex Health Challenges
✅ Neutraceutical Recommendations
✅ Advanced Translational Nutrigenomics*
✅ Nutrigenomics, Proteomics, Metabalomics
✅ Care Plans (Advanced Clinical Practice) 
 
We present, bridge, and connect these various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.     

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.     

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.     

It is all about.   

LIVING, LOVING & MATTERING     

Join us in improving your health.     

Blessings,     

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone: 
phone: 915-850-0900   

Licensed in Texas & New Mexico*         

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.     

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.     

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.     
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*     

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: 
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com 

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

Join us for a fascinating journey through the world of personal injuries in this revealing video. We'll delve into the overlooked side of traumas and how they affect our bodies in ways we might not even realize. From ankle twists to lingering headaches, discover how untreated injuries can snowball into bigger health issues over time. Let's unravel the mysteries together and learn why it's crucial to address injuries early for better long-term health.

Our care plans are base on Functional Medicine as a systems approach based on biology that focuses on identifying and addressing the root cause of disease. We focus on the paradigm that symptom or differential diagnosis may be one of many contributing factors to an individual's illness.

This approach shifts from the traditional disease-centered focus of most medical practices to a more holistic person-centered approach.

Our discussions team includes Integrative Doctors, Functional Medicine Experts, Nutritionists, Health Coaches, Chiropractors, Physical Medicine Doctors, Therapists, and Exercise Performance Specialists.
We provide clinical insights, treatment options, and methods to achieve clinically sound, specific measured goals.*

Functional & Integrative Health Live Events *
? Stress Hormones & Health
? Gut Health, Inflammation & Auto-Immunity*
? Musculoskeletal Rehabilitation
? Fibromyalgia & Inflammation
? Diabetes & Autoimmunity*
? Weight Loss
? Body Composition Analysis
? Thyroid Dysfunction*
? Autoimmune Disorder*
? Heart Disease & Inflammation*
? Agility & Mobility
? Injury Recovery Programs
? Complex Lower Back Pain Recovery Plans
? Severe Sciatica Syndromes
? Other Complex Health Challenges
? Neutraceutical Recommendations
? Advanced Translational Nutrigenomics*
? Nutrigenomics, Proteomics, Metabalomics
? Care Plans (Advanced Clinical Practice)

We present, bridge, and connect these various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.

It is all about.

LIVING, LOVING & MATTERING

Join us in improving your health.

Blessings,

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone:
phone: 915-850-0900

Licensed in Texas & New Mexico*

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information:
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

1 0

YouTube Video VVV5NTNGNC1RbUg3WVdEQ1NHUnF4T0VRLmNFbnhXMWk1bHNr

Beyond the Surface: Understanding the Effects of Personal Injury | El Paso, Tx (2024)

Dr. Alexander Jimenez 48 views April 15, 2024 9:37 am

Welcome to our channel! In this enlightening video, Alexander Jimenez delves deep into osteoarthritis, a widespread condition affecting millions worldwide. Unlike mere wear and tear, osteoarthritis is a complex disease with profound impacts on daily life. But fear not, as we explore the transformative role of chiropractic care in managing and alleviating osteoarthritis symptoms, offering hope and holistic solutions.

From understanding the intricacies of osteoarthritis to uncovering the benefits of chiropractic interventions, this video navigates through diagnosis, conventional treatments, and the empowering potential of chiropractic care. Discover how chiropractic techniques, tailored to individual needs, promote pain relief, improve mobility, and enhance overall well-being.

Empowering patients through education and self-management, chiropractic care emerges as a pivotal player in the comprehensive treatment of osteoarthritis. Join us on this journey towards holistic healing and wellness. Subscribe to our channel and become part of our health-conscious community dedicated to empowering lives through chiropractic care. Together, let's embark on a path to better joint health and a brighter future. Don't forget to like, share, and connect with us for more insightful content. Thank you for watching, and here's to your vibrant health!

We present, bridge, and connect various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.     

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.     

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.     

It is all about.   

LIVING, LOVING & MATTERING     

Join us in improving your health.     

Blessings,     

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone: 
phone: 915-850-0900   

Licensed in Texas & New Mexico*         

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.     

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.     

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.     
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*     

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: 
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com 

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

Welcome to our channel! In this enlightening video, Alexander Jimenez delves deep into osteoarthritis, a widespread condition affecting millions worldwide. Unlike mere wear and tear, osteoarthritis is a complex disease with profound impacts on daily life. But fear not, as we explore the transformative role of chiropractic care in managing and alleviating osteoarthritis symptoms, offering hope and holistic solutions.

From understanding the intricacies of osteoarthritis to uncovering the benefits of chiropractic interventions, this video navigates through diagnosis, conventional treatments, and the empowering potential of chiropractic care. Discover how chiropractic techniques, tailored to individual needs, promote pain relief, improve mobility, and enhance overall well-being.

Empowering patients through education and self-management, chiropractic care emerges as a pivotal player in the comprehensive treatment of osteoarthritis. Join us on this journey towards holistic healing and wellness. Subscribe to our channel and become part of our health-conscious community dedicated to empowering lives through chiropractic care. Together, let's embark on a path to better joint health and a brighter future. Don't forget to like, share, and connect with us for more insightful content. Thank you for watching, and here's to your vibrant health!

We present, bridge, and connect various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.

It is all about.

LIVING, LOVING & MATTERING

Join us in improving your health.

Blessings,

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone:
phone: 915-850-0900

Licensed in Texas & New Mexico*

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information:
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

2 0

YouTube Video VVV5NTNGNC1RbUg3WVdEQ1NHUnF4T0VRLkpYeFYwaDdfWTdr

Chiropractic Solutions for Osteoarthritis | El Paso, Tx (2024)

Dr. Alexander Jimenez 62 views April 11, 2024 1:23 pm

Today we discuss how chiropractic care can be a powerful tool in your personal injury rehabilitation journey.

We will talk about the benefits of chiropractic care for pain relief and mobility improvement.
How chiropractors work alongside other healthcare professionals for a holistic recovery plan.
Getting the most out of your chiropractic treatment after an injury, and more!

Get back to feeling your best, naturally!

Our discussions team includes Integrative Doctors, Functional Medicine Experts, Nutritionists, Health Coaches, Chiropractors, Physical Medicine Doctors, Therapists, and Exercise Performance Specialists.       
We provide clinical insights, treatment options, and methods to achieve clinically sound, specific measured goals.*     

Functional & Integrative Health Live Events *   
✅ Stress Hormones & Health 
✅ Gut Health, Inflammation & Auto-Immunity* 
✅ Musculoskeletal Rehabilitation
✅ Fibromyalgia & Inflammation 
✅ Diabetes & Autoimmunity* 
✅ Weight Loss 
✅ Body Composition Analysis
✅ Thyroid Dysfunction* 
✅ Autoimmune Disorder*
✅ Heart Disease & Inflammation*
✅ Agility & Mobility 
✅ Injury Recovery Programs 
✅ Complex Lower Back Pain Recovery Plans 
✅ Severe Sciatica Syndromes 
✅ Other Complex Health Challenges
✅ Neutraceutical Recommendations
✅ Advanced Translational Nutrigenomics*
✅ Nutrigenomics, Proteomics, Metabalomics
✅ Care Plans (Advanced Clinical Practice) 
 
We present, bridge, and connect these various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.     

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.     

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.     

It is all about.   

LIVING, LOVING & MATTERING     

Join us in improving your health.     

Blessings,     

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone: 
phone: 915-850-0900   

Licensed in Texas & New Mexico*         

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.     

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.     

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.     
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*     

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: 
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com 

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

Today we discuss how chiropractic care can be a powerful tool in your personal injury rehabilitation journey.

We will talk about the benefits of chiropractic care for pain relief and mobility improvement.
How chiropractors work alongside other healthcare professionals for a holistic recovery plan.
Getting the most out of your chiropractic treatment after an injury, and more!

Get back to feeling your best, naturally!

Our discussions team includes Integrative Doctors, Functional Medicine Experts, Nutritionists, Health Coaches, Chiropractors, Physical Medicine Doctors, Therapists, and Exercise Performance Specialists.
We provide clinical insights, treatment options, and methods to achieve clinically sound, specific measured goals.*

Functional & Integrative Health Live Events *
? Stress Hormones & Health
? Gut Health, Inflammation & Auto-Immunity*
? Musculoskeletal Rehabilitation
? Fibromyalgia & Inflammation
? Diabetes & Autoimmunity*
? Weight Loss
? Body Composition Analysis
? Thyroid Dysfunction*
? Autoimmune Disorder*
? Heart Disease & Inflammation*
? Agility & Mobility
? Injury Recovery Programs
? Complex Lower Back Pain Recovery Plans
? Severe Sciatica Syndromes
? Other Complex Health Challenges
? Neutraceutical Recommendations
? Advanced Translational Nutrigenomics*
? Nutrigenomics, Proteomics, Metabalomics
? Care Plans (Advanced Clinical Practice)

We present, bridge, and connect these various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.

It is all about.

LIVING, LOVING & MATTERING

Join us in improving your health.

Blessings,

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone:
phone: 915-850-0900

Licensed in Texas & New Mexico*

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information:
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

2 0

YouTube Video VVV5NTNGNC1RbUg3WVdEQ1NHUnF4T0VRLkpmZkpIUE9OQy00

Personal Injury Rehabilitation | El Paso, Tx (2024)

Dr. Alexander Jimenez 48 views March 12, 2024 8:34 am

Explore the transformative power of movement as chiropractors unveil the art of healing through motion. Discover how gentle adjustments and therapeutic exercises pave the path to holistic wellness in this enlightening journey into the world of chiropractic care.

We present, bridge, and connect various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.     

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.     

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.     

It is all about.   

LIVING, LOVING & MATTERING     

Join us in improving your health.     

Blessings,     

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone: 
phone: 915-850-0900   

Licensed in Texas & New Mexico*         

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.     

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.     

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.     
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*     

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: 
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com 

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

Explore the transformative power of movement as chiropractors unveil the art of healing through motion. Discover how gentle adjustments and therapeutic exercises pave the path to holistic wellness in this enlightening journey into the world of chiropractic care.

We present, bridge, and connect various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.

It is all about.

LIVING, LOVING & MATTERING

Join us in improving your health.

Blessings,

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone:
phone: 915-850-0900

Licensed in Texas & New Mexico*

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information:
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

1 2

YouTube Video VVV5NTNGNC1RbUg3WVdEQ1NHUnF4T0VRLkdLUVJ5V3dWeXpV

Movement Medicine: Chiropractic Care | El Paso, Tx (2024)

Dr. Alexander Jimenez 67 views March 10, 2024 1:27 pm

#alternativemedicine

Dr. Alexander Jimenez 48 views February 29, 2024 5:05 pm

In this video, we delve into the holistic approach of chiropractors, seamlessly blending traditional techniques with modern integrative practices. Discover how chiropractors synergize their expertise with various medical disciplines, offering patients a comprehensive and personalized approach to wellness. From spinal adjustments to nutritional guidance, acupuncture, and mindfulness techniques, witness the transformative power of integrating chiropractic care into the broader spectrum of holistic healthcare.

We present, bridge, and connect various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.     

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.     

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.     

It is all about.   

LIVING, LOVING & MATTERING     

Join us in improving your health.     

Blessings,     

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone: 
phone: 915-850-0900   

Licensed in Texas & New Mexico*         

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.     

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.     

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.     
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*     

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: 
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com 

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

In this video, we delve into the holistic approach of chiropractors, seamlessly blending traditional techniques with modern integrative practices. Discover how chiropractors synergize their expertise with various medical disciplines, offering patients a comprehensive and personalized approach to wellness. From spinal adjustments to nutritional guidance, acupuncture, and mindfulness techniques, witness the transformative power of integrating chiropractic care into the broader spectrum of holistic healthcare.

We present, bridge, and connect various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.

It is all about.

LIVING, LOVING & MATTERING

Join us in improving your health.

Blessings,

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone:
phone: 915-850-0900

Licensed in Texas & New Mexico*

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information:
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

1 1

YouTube Video VVV5NTNGNC1RbUg3WVdEQ1NHUnF4T0VRLnV6VjNfQmlRdnlV

Beyond Adjustments: Chiropractic and Integrative Healthcare | El Paso, Tx (2024)

Dr. Alexander Jimenez 48 views February 15, 2024 3:49 pm

Discover expert insights, practical tips, and effective exercises to reclaim your mobility and bid farewell to sciatica discomfort. Whether you're a long-time sufferer or curious about preventative measures, this video is your ultimate guide to achieving a pain-free, active lifestyle. Say goodbye to sciatica and hello to a healthier you! 🚀 #ChiropracticCare #SciaticaRelief #RehabilitationTips

 Our care plans are base on Functional Medicine as a systems approach based on biology that focuses on identifying and addressing the root cause of disease. We focus on the paradigm that symptom or differential diagnosis may be one of many contributing factors to an individual's illness.   

This approach shifts from the traditional disease-centered focus of most medical practices to a more holistic person-centered approach.       

Our discussions team includes Integrative Doctors, Functional Medicine Experts, Nutritionists, Health Coaches, Chiropractors, Physical Medicine Doctors, Therapists, and Exercise Performance Specialists.       
We provide clinical insights, treatment options, and methods to achieve clinically sound, specific measured goals.*     

Functional & Integrative Health Live Events *   
✅ Stress Hormones & Health 
✅ Gut Health, Inflammation & Auto-Immunity* 
✅ Musculoskeletal Rehabilitation
✅ Fibromyalgia & Inflammation 
✅ Diabetes & Autoimmunity* 
✅ Weight Loss 
✅ Body Composition Analysis
✅ Thyroid Dysfunction* 
✅ Autoimmune Disorder*
✅ Heart Disease & Inflammation*
✅ Agility & Mobility 
✅ Injury Recovery Programs 
✅ Complex Lower Back Pain Recovery Plans 
✅ Severe Sciatica Syndromes 
✅ Other Complex Health Challenges
✅ Neutraceutical Recommendations
✅ Advanced Translational Nutrigenomics*
✅ Nutrigenomics, Proteomics, Metabalomics
✅ Care Plans (Advanced Clinical Practice) 
 
We present, bridge, and connect these various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.     

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.     

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.     

It is all about.   

LIVING, LOVING & MATTERING     

Join us in improving your health.     

Blessings,     

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone: 
phone: 915-850-0900   

Licensed in Texas & New Mexico*         

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.     

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.     

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.     
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*     

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: 
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com 

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

Discover expert insights, practical tips, and effective exercises to reclaim your mobility and bid farewell to sciatica discomfort. Whether you're a long-time sufferer or curious about preventative measures, this video is your ultimate guide to achieving a pain-free, active lifestyle. Say goodbye to sciatica and hello to a healthier you! ? #ChiropracticCare #SciaticaRelief #RehabilitationTips

Our care plans are base on Functional Medicine as a systems approach based on biology that focuses on identifying and addressing the root cause of disease. We focus on the paradigm that symptom or differential diagnosis may be one of many contributing factors to an individual's illness.

This approach shifts from the traditional disease-centered focus of most medical practices to a more holistic person-centered approach.

Our discussions team includes Integrative Doctors, Functional Medicine Experts, Nutritionists, Health Coaches, Chiropractors, Physical Medicine Doctors, Therapists, and Exercise Performance Specialists.
We provide clinical insights, treatment options, and methods to achieve clinically sound, specific measured goals.*

Functional & Integrative Health Live Events *
? Stress Hormones & Health
? Gut Health, Inflammation & Auto-Immunity*
? Musculoskeletal Rehabilitation
? Fibromyalgia & Inflammation
? Diabetes & Autoimmunity*
? Weight Loss
? Body Composition Analysis
? Thyroid Dysfunction*
? Autoimmune Disorder*
? Heart Disease & Inflammation*
? Agility & Mobility
? Injury Recovery Programs
? Complex Lower Back Pain Recovery Plans
? Severe Sciatica Syndromes
? Other Complex Health Challenges
? Neutraceutical Recommendations
? Advanced Translational Nutrigenomics*
? Nutrigenomics, Proteomics, Metabalomics
? Care Plans (Advanced Clinical Practice)

We present, bridge, and connect these various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.

It is all about.

LIVING, LOVING & MATTERING

Join us in improving your health.

Blessings,

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone:
phone: 915-850-0900

Licensed in Texas & New Mexico*

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information:
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

1 0

YouTube Video VVV5NTNGNC1RbUg3WVdEQ1NHUnF4T0VRLjJHS0xUTnVCZklB

Reclaim Your Mobility: Chiropractic Care for Sciatica Recovery | El Paso, Tx (2024)

Dr. Alexander Jimenez 83 views January 27, 2024 2:49 pm

Discover the powerful impact of chiropractic solutions in promoting healing and restoring well-being. Join us in exploring the path to recovery and reclaiming your health post-trauma. Your wellness journey starts here!

 Our care plans are base on Functional Medicine as a systems approach based on biology that focuses on identifying and addressing the root cause of disease. We focus on the paradigm that symptom or differential diagnosis may be one of many contributing factors to an individual's illness.   

This approach shifts from the traditional disease-centered focus of most medical practices to a more holistic person-centered approach.       

Our discussions team includes Integrative Doctors, Functional Medicine Experts, Nutritionists, Health Coaches, Chiropractors, Physical Medicine Doctors, Therapists, and Exercise Performance Specialists.       
We provide clinical insights, treatment options, and methods to achieve clinically sound, specific measured goals.*     

Functional & Integrative Health Live Events *   
✅ Stress Hormones & Health 
✅ Gut Health, Inflammation & Auto-Immunity* 
✅ Musculoskeletal Rehabilitation
✅ Fibromyalgia & Inflammation 
✅ Diabetes & Autoimmunity* 
✅ Weight Loss 
✅ Body Composition Analysis
✅ Thyroid Dysfunction* 
✅ Autoimmune Disorder*
✅ Heart Disease & Inflammation*
✅ Agility & Mobility 
✅ Injury Recovery Programs 
✅ Complex Lower Back Pain Recovery Plans 
✅ Severe Sciatica Syndromes 
✅ Other Complex Health Challenges
✅ Neutraceutical Recommendations
✅ Advanced Translational Nutrigenomics*
✅ Nutrigenomics, Proteomics, Metabalomics
✅ Care Plans (Advanced Clinical Practice) 
 
We present, bridge, and connect these various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.     

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.     

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.     

It is all about.   

LIVING, LOVING & MATTERING     

Join us in improving your health.     

Blessings,     

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone: 
phone: 915-850-0900   

Licensed in Texas & New Mexico*         

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.     

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.     

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.     
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*     

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information: 
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com 

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

Discover the powerful impact of chiropractic solutions in promoting healing and restoring well-being. Join us in exploring the path to recovery and reclaiming your health post-trauma. Your wellness journey starts here!

Our care plans are base on Functional Medicine as a systems approach based on biology that focuses on identifying and addressing the root cause of disease. We focus on the paradigm that symptom or differential diagnosis may be one of many contributing factors to an individual's illness.

This approach shifts from the traditional disease-centered focus of most medical practices to a more holistic person-centered approach.

Our discussions team includes Integrative Doctors, Functional Medicine Experts, Nutritionists, Health Coaches, Chiropractors, Physical Medicine Doctors, Therapists, and Exercise Performance Specialists.
We provide clinical insights, treatment options, and methods to achieve clinically sound, specific measured goals.*

Functional & Integrative Health Live Events *
? Stress Hormones & Health
? Gut Health, Inflammation & Auto-Immunity*
? Musculoskeletal Rehabilitation
? Fibromyalgia & Inflammation
? Diabetes & Autoimmunity*
? Weight Loss
? Body Composition Analysis
? Thyroid Dysfunction*
? Autoimmune Disorder*
? Heart Disease & Inflammation*
? Agility & Mobility
? Injury Recovery Programs
? Complex Lower Back Pain Recovery Plans
? Severe Sciatica Syndromes
? Other Complex Health Challenges
? Neutraceutical Recommendations
? Advanced Translational Nutrigenomics*
? Nutrigenomics, Proteomics, Metabalomics
? Care Plans (Advanced Clinical Practice)

We present, bridge, and connect these various health programs, functional medicine protocols, fitness methods, injury recovery programs, and offer complete wellness packages.

To that end, we shed light and offer treatment options and bring a deep understanding of the real underlying causes of those suffering from acute and interconnected chronic degenerative disorders.

Ultimately, we empower you to achieve and maintain your personalized, healthy way of living by understanding the root causes of disorders.

It is all about.

LIVING, LOVING & MATTERING

Join us in improving your health.

Blessings,

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG*
email: coach@elpasofunctionalmedicine.com phone:
phone: 915-850-0900

Licensed in Texas & New Mexico*

Notice: Our information scope is limited to musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present talks and clinical collaboration with specialists from a wide array of disciplines. Each specialist in our events is governed by their professional scope of practice and their jurisdiction of licensure.

The information in these events is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.

Our presentations are designed to share knowledge and information from Dr. Jimenez's research, experience, and collaborative functional medicine community. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional.
We use and discuss functional health & wellness protocols to treat and support the musculoskeletal system's care for injuries or disorders. Our events, webinars, posts, topics, subjects, and insights cover clinical matters, issues, and issues that relate and support, directly or indirectly, our clinical scope of practice.*

Subscribe: http://bit.ly/drjyt

Facebook Clinical Page: https://www.facebook.com/dralexjimenez/
Facebook Injuries Page: https://www.facebook.com/elpasochiropractor/
Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeuropathyCenter/

Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2
Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ

Clinical Testimonies: https://www.dralexjimenez.com/category/testimonies/

Information:
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com
Sports Injury Site: https://chiropracticscientist.com
Back Injury Site: https://www.elpasobackclinic.com
Functional Medicine: https://wellnessdoctorrx.com

Twitter: https://twitter.com/dralexjimenez
Twitter: https://twitter.com/crossfitdoctor

DISCLAIMER: https://dralexjimenez.com/legal-disclaimer/

1 0

YouTube Video VVV5NTNGNC1RbUg3WVdEQ1NHUnF4T0VRLlk5TXh5LXZRNFdz

Chiropractic Care for Healing After Trauma | El Paso, Tx (2024)

Dr. Alexander Jimenez 51 views January 16, 2024 1:55 pm

Again, We Welcome You.

Our Purpose & Passions: I am a Doctor of Chiropractic specializing in progressive, cutting-edge therapies and functional rehabilitation procedures focused on clinical physiology, total health, practical strength training, and complete conditioning. We focus on restoring normal body functions after neck, back, spinal and soft tissue injuries.

We use Specialized Chiropractic Protocols, Wellness Programs, Functional & Integrative Nutrition, Agility & Mobility Fitness Training, and Rehabilitation Systems for all ages.

As an extension to effective rehabilitation, we too offer our patients, disabled veterans, athletes, and young and elder a diverse portfolio of strength equipment, high-performance exercises, and advanced agility treatment options. We have teamed up with the city’s premier doctors, therapists, and trainers to provide high-level competitive athletes the possibility to push themselves to their highest abilities within our facilities.

We’ve been blessed to use our methods with thousands of El Pasoans over the last three decades allowing us to restore our patients’ health and fitness while implementing researched non-surgical methods and functional wellness programs.

Our programs are natural and use the body’s ability to achieve specific measured goals, rather than introducing harmful chemicals, controversial hormone replacement, unwanted surgeries, or addictive drugs. We want you to live a functional life that is fulfilled with more energy, a positive attitude, better sleep, and less pain. Our goal is to ultimately empower our patients to maintain the healthiest way of living.

With a bit of work, we can achieve optimal health together, no matter the age or disability.

Join us in improving your health for you and your family.

It’s all about: LIVING, LOVING & MATTERING!

Welcome & God Bless

EL PASO LOCATIONS

East Side: Main Clinic*
11860 Vista Del Sol, Ste 128
Phone: 915-412-6677

Central: Rehabilitation Center
6440 Gateway East, Ste B
Phone: 915-850-0900

North East Rehabilitation & Fitness Center
7100 Airport Blvd, Ste. C
Phone: 915-412-6677

Dr. Alex Jimenez DC, MSACP, CIFM, ATN, IFMCP
My Digital Business Card

Clinic Location 1

Address: 11860 Vista Del Sol Dr Suite 128
El Paso, TX 79936
Phone
: (915) 412-6677
Email: Send Email
Web: www.DrAlexJimenez.com

Clinic Location 2

Address: 6440 Gateway East, Building B
El Paso, TX 79905
Phone: (915) 850-0900
Email: Send Email
Web: www.ElPasoBackClinic.com

Clinic Location 3

Address: 1700 N Zaragoza Rd # 117
El Paso, TX 79936
Phone: (915) 850-0900
Email: Send Email
Web: www.ChiropracticScientist.com

Push As Rx Crossfit & Rehab

Address: 6440 Gateway East, Building B
El Paso, TX 79905
Phone
: (915) 412-6677
EmailSend Email
Webwww.PushAsRx.com

Push 24/7

Address: 1700 E Cliff Dr
El Paso, TX 79902
Phone
: (915) 412-6677
EmailSend Email
Webwww.PushAsRx.com

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Post Disclaimer

Professional Scope of Practice *

The information herein on "El Paso, TX Oxidative Stress and Antioxidant Defense" is not intended to replace a one-on-one relationship with a qualified health care professional or licensed physician and is not medical advice. We encourage you to make healthcare decisions based on your research and partnership with a qualified healthcare professional.

Blog Information & Scope Discussions

Our information scope is limited to Chiropractic, musculoskeletal, physical medicines, wellness, contributing etiological viscerosomatic disturbances within clinical presentations, associated somatovisceral reflex clinical dynamics, subluxation complexes, sensitive health issues, and/or functional medicine articles, topics, and discussions.

We provide and present clinical collaboration with specialists from various disciplines. Each specialist is governed by their professional scope of practice and their jurisdiction of licensure. We use functional health & wellness protocols to treat and support care for the injuries or disorders of the musculoskeletal system.

Our videos, posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate to and directly or indirectly support our clinical scope of practice.*

Our office has reasonably attempted to provide supportive citations and has identified the relevant research study or studies supporting our posts. We provide copies of supporting research studies available to regulatory boards and the public upon request.

We understand that we cover matters that require an additional explanation of how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez, DC, or contact us at 915-850-0900.

We are here to help you and your family.

Blessings

Dr. Alex Jimenez DC, MSACP, RN*, CCST, IFMCP*, CIFM*, ATN*

email: coach@elpasofunctionalmedicine.com

Licensed as a Doctor of Chiropractic (DC) in Texas & New Mexico*
Texas DC License # TX5807, New Mexico DC License # NM-DC2182

Licensed as a Registered Nurse (RN*) in Florida
Florida License RN License # RN9617241 (Control No. 3558029)
Compact Status: Multi-State License: Authorized to Practice in 40 States*

Presently Matriculated: ICHS: MSN* FNP (Family Nurse Practitioner Program)

Dr. Alex Jimenez DC, MSACP, RN* CIFM*, IFMCP*, ATN*, CCST
My Digital Business Card